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Astım ve Ağız Diş Sağlığı Üzerindeki Etkileri

Year 2016, Volume: 17 Issue: 1, 35 - 38, 01.04.2016

Abstract

Astım, hava yollarının aşırı duyarlılığı ve hava yollarının geri dönüşümlü tıkanmasıyla karakterize, kronik enflamatuvar bir hastalıktır. Genetik ve çevresel faktörler astım etiyolojisinde rol oynayabilir. Dünyada yaklaşık 300 milyon insan astım tanısı almıştır ve 2025 yılına kadar 100 milyon yeni tanı olması beklenmektedir. Ülkemizde yapılan çalışmalarda astım prevalansının %1,5 ile % 9,4 aralığında olduğu saptanmıştır. Literatürde dünyada ve ülkemizde artma eğiliminde olan astımın tedavisinde kullanılan ilaçların ağız ve diş sağlığı üzerindeki etkilerini inceleyen çok sayıda çalışma mevcuttur. Bununla beraber, bu ilaçların ağız diş sağlığına etkileri konusunda fikir birliği yoktur. Astım ilaçları ve ağız diş sağlığı üzerindeki etkileri konusunda bilgi sahibi olmak ve gerekli önlemleri almak ağız diş sağlığını korumak için önemlidir. Bu derlemede, astım ilaçlarını ağız diş sağlığı üzerindeki etkilerinin değerlendirilmesine ek olarak alınabilecek önlemler de değerlendirilmiştir

References

  • 1. Ehsani S, Moin M, Meighani G, Pourhashemi SJ, Khayatpisheh H, Yarahmadi N. Oral health status in preschool asthmatic children in Iran. Iran J Allergy Asthma Immunol 2013; 12: 254-61.
  • 2. Dursun GB, Mungan D, Oğuzülgen K, Türktaş H, Yıldız F, Yorgancıoğlu A. Türk Toraks Derneği Astım Tanı ve Tedavi Rehberi İstanbul; 2009.
  • 3. Bayram I, Guneser-Kendirli S, Yilmaz M, Altintas DU, Alparslan N, Bingol-Karakoc G. The prevalence of asthma and allergic diseases in children of school age in Adana in southern Turkey. Turk J Pediatr 2004; 46: 221-5.
  • 4. Demir E, Tanac R, Can D, Gulen F, Yenigun A, Aksakal K. Is there an increase in the prevalence of allergic diseases among schoolchildren from the Aegean region of Turkey? Allergy Asthma Proc 2005; 26: 410-4.
  • 5. Lipworth BJ. Systemic adverse effects of inhaled corticosteroid therapy: A systematic review and meta-analysis. Arch Intern Med 1999; 159: 941-55.
  • 6. Barnes PJ. Efficacy of inhaled corticosteroids in asthma. J Allergy Clin Immunol 1998; 102: 531-8.
  • 7. Reddy DK, Hegde AM, Munshi AK. Dental caries status of children with bronchial asthma. J Clin Pediatr Dent 2003; 27: 293-5.
  • 8. Shashikiran ND, Reddy VV, Raju PK. Effect of antiasthmatic medication on dental disease: Dental caries and periodontal disease. J Indian Soc Pedod Prev Dent 2007; 25: 65-8.
  • 9. Saraclar Y, Kuyucu S, Tuncer A, Sekerel B, Sackesen C, Kocabas C. Prevalence of asthmatic phenotypes and bronchial hyperresponsiveness in Turkish schoolchildren: An International Study of Asthma and Allergies in Childhood (ISAAC) phase 2 study. Ann Allergy Asthma Immunol 2003; 91: 477-84.
  • 10. Armfield JM. High caries children in Australia: A ‘tail’ of caries distribution. Aust Dent J 2005; 50: 204-6.
  • 11. Ersin NK, Gulen F, Eronat N, Cogulu D, Demir E, Tanac R, et al. Oral and dental manifestations of young asthmatics related to medication, severity and duration of condition. Pediatr Int 2006; 48: 549-54.
  • 12. McDerra EJ, Pollard MA, Curzon ME. The dental status of asthmatic British school children. Pediatr Dent 1998; 20: 281-7.
  • 13. Ryberg M, Moller C, Ericson T. Effect of beta 2-adrenoceptor agonists on saliva proteins and dental caries in asthmatic children. J Dent Res 1987; 66: 1404-6.
  • 14. Kargul B, Tanboga I, Ergeneli S, Karakoc F, Dagli E. Inhaler medicament effects on saliva and plaque pH in asthmatic children. J Clin Pediatr Dent 1998; 22: 137-40.
  • 15. Thomas MS, Parolia A, Kundabala M, Vikram M. Asthma and oral health: A review. Aust Dent J 2010; 55: 128-33.
  • 16. Kenny DJ, Somaya P. Sugar load of oral liquid medications on chronically ill children. J Can Dent Assoc 1989; 55: 43-6.
  • 17. Al-Dlaigan YH, Shaw L, Smith AJ. Is there a relationship between asthma and dental erosion? A case control study. Int J Paediatr Dent 2002; 12: 189-200.
  • 18. Harding SM. Gastroesophageal reflux, asthma, and mechanisms of interaction. Am J Med 2001; 111 Suppl 8A: 8S-12S.
  • 19. Hyyppa T. Gingival IgE and histamine concentrations in patients with asthma and in patients with periodontitis. J Clin Periodontol 1984; 11: 132-7.
  • 20. Irwin RS, Richardson ND. Side effects with inhaled corticosteroids: The physician’s perception. Chest 2006; 130(1 Suppl): 41S-53S.
  • 21. Mortimer KJ, Harrison TW, Tattersfield AE. Effects of inhaled corticosteroids on bone. Ann Allergy Asthma Immunol 2005; 94: 15-21.
  • 22. Han ER, Choi IS, Kim HK, Kang YW, Park JG, Lim JR, Seo JH, Choi JH. Inhaled corticosteroid-related tooth problems in asthmatics. J Asthma 2009; 46: 160-4.
  • 23. Kurt E, Yildirim H, Kiraz N, Orman A, Metintas M, Akgun Y, et al. Oropharyngeal candidiasis with dry-powdered fluticasone propionate: 500 microg/day versus 200 microg/day. Allergol Immunopathol (Madr) 2008; 36: 17-20.
  • 24. Fukushima C, Matsuse H, Saeki S, Kawano T, Machida I, Kondo Y, et al. Salivary IgA and oral candidiasis in asthmatic patients treated with inhaled corticosteroid. J Asthma 2005; 42: 601-4.
  • 25. Torres SR, Peixoto CB, Caldas DM, Silva EB, Akiti T, Nucci M, et al. Relationship between salivary flow rates and Candida counts in subjects with xerostomia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002; 93: 149-54.
  • 26. Epstein JB, Komiyama K, Duncan D. Oral topical steroids and secondary oral candidiasis. J Oral Med 1986; 41: 223-7, 273.

Asthma and Its Impacts on Oral Health

Year 2016, Volume: 17 Issue: 1, 35 - 38, 01.04.2016

Abstract

Asthma is a chronic inflammatory disease characterized by airway hyperresponsiveness and reversible airflow obstruction. Genetic factors and environmental factors may play a role in the etiology of asthma. An approximately 300 million people worldwide have been diagnosed with asthma and there may be an additional 100 million diagnosis by 2025. Studies conducted in Turkey reported a prevalence between 1.5% and 9.4%. In the literature, there are many studies investigating the impacts of the medications used for asthma, which has a tendency to increase in our country and in the world, on oral health. However, no consensus has yet been established regarding whether these medications affect oral health. It is important to have knowledge about the impacts of asthma medications on oral and dental health and to take the necessary precautions in order to maintain oral and dental health. In this review, in addition to investigation of the impact of asthma medications on oral health, possible measures that can be taken were also evaluated.

References

  • 1. Ehsani S, Moin M, Meighani G, Pourhashemi SJ, Khayatpisheh H, Yarahmadi N. Oral health status in preschool asthmatic children in Iran. Iran J Allergy Asthma Immunol 2013; 12: 254-61.
  • 2. Dursun GB, Mungan D, Oğuzülgen K, Türktaş H, Yıldız F, Yorgancıoğlu A. Türk Toraks Derneği Astım Tanı ve Tedavi Rehberi İstanbul; 2009.
  • 3. Bayram I, Guneser-Kendirli S, Yilmaz M, Altintas DU, Alparslan N, Bingol-Karakoc G. The prevalence of asthma and allergic diseases in children of school age in Adana in southern Turkey. Turk J Pediatr 2004; 46: 221-5.
  • 4. Demir E, Tanac R, Can D, Gulen F, Yenigun A, Aksakal K. Is there an increase in the prevalence of allergic diseases among schoolchildren from the Aegean region of Turkey? Allergy Asthma Proc 2005; 26: 410-4.
  • 5. Lipworth BJ. Systemic adverse effects of inhaled corticosteroid therapy: A systematic review and meta-analysis. Arch Intern Med 1999; 159: 941-55.
  • 6. Barnes PJ. Efficacy of inhaled corticosteroids in asthma. J Allergy Clin Immunol 1998; 102: 531-8.
  • 7. Reddy DK, Hegde AM, Munshi AK. Dental caries status of children with bronchial asthma. J Clin Pediatr Dent 2003; 27: 293-5.
  • 8. Shashikiran ND, Reddy VV, Raju PK. Effect of antiasthmatic medication on dental disease: Dental caries and periodontal disease. J Indian Soc Pedod Prev Dent 2007; 25: 65-8.
  • 9. Saraclar Y, Kuyucu S, Tuncer A, Sekerel B, Sackesen C, Kocabas C. Prevalence of asthmatic phenotypes and bronchial hyperresponsiveness in Turkish schoolchildren: An International Study of Asthma and Allergies in Childhood (ISAAC) phase 2 study. Ann Allergy Asthma Immunol 2003; 91: 477-84.
  • 10. Armfield JM. High caries children in Australia: A ‘tail’ of caries distribution. Aust Dent J 2005; 50: 204-6.
  • 11. Ersin NK, Gulen F, Eronat N, Cogulu D, Demir E, Tanac R, et al. Oral and dental manifestations of young asthmatics related to medication, severity and duration of condition. Pediatr Int 2006; 48: 549-54.
  • 12. McDerra EJ, Pollard MA, Curzon ME. The dental status of asthmatic British school children. Pediatr Dent 1998; 20: 281-7.
  • 13. Ryberg M, Moller C, Ericson T. Effect of beta 2-adrenoceptor agonists on saliva proteins and dental caries in asthmatic children. J Dent Res 1987; 66: 1404-6.
  • 14. Kargul B, Tanboga I, Ergeneli S, Karakoc F, Dagli E. Inhaler medicament effects on saliva and plaque pH in asthmatic children. J Clin Pediatr Dent 1998; 22: 137-40.
  • 15. Thomas MS, Parolia A, Kundabala M, Vikram M. Asthma and oral health: A review. Aust Dent J 2010; 55: 128-33.
  • 16. Kenny DJ, Somaya P. Sugar load of oral liquid medications on chronically ill children. J Can Dent Assoc 1989; 55: 43-6.
  • 17. Al-Dlaigan YH, Shaw L, Smith AJ. Is there a relationship between asthma and dental erosion? A case control study. Int J Paediatr Dent 2002; 12: 189-200.
  • 18. Harding SM. Gastroesophageal reflux, asthma, and mechanisms of interaction. Am J Med 2001; 111 Suppl 8A: 8S-12S.
  • 19. Hyyppa T. Gingival IgE and histamine concentrations in patients with asthma and in patients with periodontitis. J Clin Periodontol 1984; 11: 132-7.
  • 20. Irwin RS, Richardson ND. Side effects with inhaled corticosteroids: The physician’s perception. Chest 2006; 130(1 Suppl): 41S-53S.
  • 21. Mortimer KJ, Harrison TW, Tattersfield AE. Effects of inhaled corticosteroids on bone. Ann Allergy Asthma Immunol 2005; 94: 15-21.
  • 22. Han ER, Choi IS, Kim HK, Kang YW, Park JG, Lim JR, Seo JH, Choi JH. Inhaled corticosteroid-related tooth problems in asthmatics. J Asthma 2009; 46: 160-4.
  • 23. Kurt E, Yildirim H, Kiraz N, Orman A, Metintas M, Akgun Y, et al. Oropharyngeal candidiasis with dry-powdered fluticasone propionate: 500 microg/day versus 200 microg/day. Allergol Immunopathol (Madr) 2008; 36: 17-20.
  • 24. Fukushima C, Matsuse H, Saeki S, Kawano T, Machida I, Kondo Y, et al. Salivary IgA and oral candidiasis in asthmatic patients treated with inhaled corticosteroid. J Asthma 2005; 42: 601-4.
  • 25. Torres SR, Peixoto CB, Caldas DM, Silva EB, Akiti T, Nucci M, et al. Relationship between salivary flow rates and Candida counts in subjects with xerostomia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002; 93: 149-54.
  • 26. Epstein JB, Komiyama K, Duncan D. Oral topical steroids and secondary oral candidiasis. J Oral Med 1986; 41: 223-7, 273.
There are 26 citations in total.

Details

Other ID JA65RT37GM
Journal Section Collection
Authors

Sultan Keleş This is me

Nasibe Aycan Yılmaz This is me

Publication Date April 1, 2016
Published in Issue Year 2016 Volume: 17 Issue: 1

Cite

EndNote Keleş S, Yılmaz NA (April 1, 2016) Asthma and Its Impacts on Oral Health. Meandros Medical And Dental Journal 17 1 35–38.