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Trigeminal Nevraljide Radyofrekans Termokoagülasyon ve Pulse Radyofrekansla Kombine Radyofrekans Termokoagülasyonun Karşılaştırılması

Year 2025, Volume: 26 Issue: 1, 63 - 68, 20.03.2025
https://doi.org/10.69601/meandrosmdj.1589421

Abstract

Amaç Bu çalışmanın amacı trigeminal nevraljide etkinliği artırmak için yüksek sıcaklıklarda uygulanan Radyofrekans termokoagülasyon (RFT) ile Pulse Radyofrekans (PRF) kombinasyonlu RFT tedavisini karşılaştırmaktır.
Metod: Mayıs 2014-Mart 2022 tarihleri arasında Algoloji kliniğinde trigeminal nevralji nedeni ile kombine RFT (85°C, 60 saniye) + PRF (42°C, 240 saniye) ve RFT (85°C, 60 saniye) uygulanan hastaların başvurudaki demografik ve klinik muayene bulguları, VAS skorları kaydedildi. İşlem sonrası 1. Ay, 12. Ay ve 24 ay takipte VAS ağrı skorları, klinik ve nörolojik muayene, ağrı kontrol süresi, nüks, gelişen komplikasyon bulguları kaydedildi.
Sonuçlar: 43 hastanın sonuçları (24 kadın, 19 erkek); 20 hastaya yüksek sıcaklıkta RFT, 23 hastaya PRF+RFT uygulanma durumuna göre 2 grupta değerlendirildi. İşlem sonrası 1. Ay, 12. Ay ve 24. Ay takiplerde her iki grupta da VAS skorları işlem öncesine göre anlamlı olarak daha düşüktü (sırasıyla p<0.001, p<0.001). Ağrı kontrol süresi RFT grubunda 25.8±4.8 ay, PRF+RFT grubunda 25±3.4 aydı (p=0.5). 24 ay takipte 3 hastada (2 hasta RFT grubu, 1 hasta PRF+RFT grubu) nüks gözlendi (p=0.5). RFT grubunda 10 hastada, PRF+RFT grubunda 5 hastada komplikasyon (masseter atoni ve dermatomal hipoestezi) vardı (p=0.052). Komplikasyonların gerileme süresi RFT grubunda ortalama 75±35.61 gün, RFT+PRF grubunda ortalama 40±18.17 gündü (p=0.04). Hiçbir hastada geri dönüşümsüz bir komplikasyon kaydedilmedi.
Tartışma: Trigeminal nevraljide yüksek sıcaklıklarda uygulanan RFT ağrı kontrol süresi ve nüks önlemek için etkilidir. Yüksek sıcaklıklarda RFT tedavisine kombine edilen PRF, komplikasyonları önlemek ve yan etki gerileme süresini kısaltmak için uygun bir tedavi seçimidir.

References

  • 1. Asplund P, Blomstedt P, Bergenheim AT. Percutaneous Balloon Compression vs Percutaneous Retrogasserian Glycerol Rhizotomy for the Primary Treatment of Trigeminal Neuralgia. Neurosurgery. 2016 Mar;78(3):421-8; discussion 428. doi: 10.1227/NEU.0000000000001059.
  • 2. Kanpolat Y, Savas A, Bekar A, Berk C. Percutaneous controlled radiofrequency trigeminal rhizotomy for the treatment of idiopathic trigeminal neuralgia: 25-year experience with 1,600 patients. Neurosurgery. 2001 Mar;48(3):524-32; discussion 532-4. doi: 10.1097/00006123-200103000-00013.
  • 3. Ding Y, Li H, Hong T, Zhu Y, Yao P, Zhou G. Combination of Pulsed Radiofrequency with Continuous Radiofrequency Thermocoagulation at Low Temperature Improves Efficacy and Safety in V2/V3 Primary Trigeminal Neuralgia. Pain Physician. 2018 Sep;21(5):E545-E553.
  • 4. Arıcı T, Kurcaloğlu M, Kılıç E, Erhan E. Radiofrequency thermocoagulation combined with pulsed radiofrequency for gasserian ganglion blockage. Agri. 2018 Oct;30(4):179-182. doi: 10.5505/agri.2018.88261.
  • 5. Hong T, Ding Y, Yao P. Long-Term Efficacy and Complications of Radiofrequency Thermocoagulation at Different Temperatures for the Treatment of Trigeminal Neuralgia. Biochem Res Int. 2020 Mar 4;2020:3854284. doi: 10.1155/2020/3854284.
  • 6. Tang YZ, Yang LQ, Yue JN, Wang XP, He LL, Ni JX. The optimal radiofrequency temperature in radiofrequency thermocoagulation for idiopathic trigeminal neuralgia: A cohort study. Medicine (Baltimore). 2016 Jul;95(28):e4103. doi: 10.1097/MD.0000000000004103.
  • 7. Yang JT, Lin M, Lee MH, Weng HH, Liao HH. Percutaneous trigeminal nerve radiofrequency rhizotomy guided by computerized tomography with three-dimensional image reconstruction. Chang Gung Med J. 2010 Nov-Dec;33(6):679-83.
  • 8. Fraioli MF, Cristino B, Moschettoni L, Cacciotti G, Fraioli C. Validity of percutaneous controlled radiofrequency thermocoagulation in the treatment of isolated third division trigeminal neuralgia. Surg Neurol. 2009 Feb;71(2):180-3. doi: 10.1016/j.surneu.2007.09.024.
  • 9. Kosugi S, Shiotani M, Otsuka Y, Suzuki T, Katori N, Hashiguchi S, Morisaki H. Long-term outcomes of percutaneous radiofrequency thermocoagulation of gasserian ganglion for 2nd- and multiple-division trigeminal neuralgia. Pain Pract. 2015 Mar;15(3):223-8. doi: 10.1111/papr.12163.
  • 10. Zheng S, Wu B, Zhao Y, Wang X, Li X, Yang L, He M, Yue J, Ni J. Masticatory Muscles Dysfunction after CT-guided Percutaneous Trigeminal Radiofrequency Thermocoagulation for Trigeminal Neuralgia: A Detailed Analysis. Pain Pract. 2015 Nov;15(8):712-9. doi: 10.1111/papr.12247.
  • 11. Fouad, W. Management of trigeminal neuralgia by radiofrequency thermocoagulation. Alexandria Journal of Medicine. 2011; 47(1), 79–86. https://doi.org/10.1016/j.ajme.2011.02.001.
  • 12. Koning MV, Koning NJ, Koning HM, van Kleef M. Relationship between Sensory Stimulation and Side Effects in Percutaneous Radiofrequency Treatment of the Trigeminal Ganglion. Pain Pract. 2014 Sep;14(7):581-7. doi: 10.1111/papr.12124.
  • 13. Yao P, Deng YY, Hong T, Wang ZB, Ma JM, Zhu YQ, Li HX, Ding YY, Pan SN. Radiofrequency thermocoagulation for V2/V3 idiopathic trigeminal neuralgia: effect of treatment temperatures on long-term clinical outcomes: A Cohort Study. Medicine (Baltimore). 2016 Jun;95(26):e4019. doi: 10.1097/MD.0000000000004019.
  • 14. Zhao WX, Wang Q, He MW, Yang LQ, Wu BS, Ni JX. Radiofrequency thermocoagulation combined with pulsed radiofrequency helps relieve postoperative complications of trigeminal neuralgia. Genet Mol Res. 2015 Jul 13;14(3):7616-23. doi: 10.4238/2015.July.13.5.
  • 15. Yao P, Hong T, Zhu YQ, Li HX, Wang ZB, Ding YY, Ma JM, Pan SN. Efficacy and safety of continuous radiofrequency thermocoagulation plus pulsed radiofrequency for treatment of V1 trigeminal neuralgia: A prospective cohort study. Medicine (Baltimore). 2016 Nov;95(44):e5247. doi: 10.1097/MD.0000000000005247. PMID: 27858881; PMCID: PMC5591129.
  • 16. Elawamy A, Abdalla EEM, Shehata GA. Effects of Pulsed Versus Conventional Versus Combined Radiofrequency for the Treatment of Trigeminal Neuralgia: A Prospective Study. Pain Physician. 2017 Sep;20(6):E873-E881. PMID: 28934792.

Comparison of Radiofrequency Thermocoagulation at High Temperatures with Combined Radiofrequency Thermocoagulation and Pulsed Radiofrequency in the Treatment of Trigeminal Neuralgia

Year 2025, Volume: 26 Issue: 1, 63 - 68, 20.03.2025
https://doi.org/10.69601/meandrosmdj.1589421

Abstract

Objective: The aim of this study was to compare the Radiofrequency Thermocoagulation (RFT) applied at high temperatures with RFT combined Pulsed Radiofrequency (PRF) to improve the efficacy in trigeminal neuralgia.
Materials and Methods: Demographic, clinical examination findings and VAS scores of the patients who underwent combined RFT + PRF and RFT for trigeminal neuralgia in the Algology clinic between May 2014 and March 2022 were recorded before the procedure and evaluated at 1 month, 12 months and 2 years after the procedure.
Results: The results of 43 patients (24 females, 19 males) were evaluated in 2 groups according to whether 20 patients underwent high-temperature RFT and 23 patients underwent PRF+RFT. At 1 month, 12 months and 24 months post-procedure follow-up, VAS scores were significantly lower in both groups compared to pre-procedure (p<0.001, p<0.001, respectively). The duration of pain control was 25.8±4.8 months in the RFT group and 25±3.4 months in the PRF+RFT group (p=0.5). At 2-year follow-up, recurrence was observed in 3 patients (2 patients in RFT group, 1 patient in PRF+RFT group) (p=0.5). Complications (masseter atony and dermatomal hypoesthesia) occurred in 10 patients in the RFT group and 5 patients in the PRF+RFT group (p=0.052). The mean time to resolution of complications was 75±35.61 days in the RFT group and 40±18.17 days in the RFT+PRF group (p=0.04). No irreversible complication was recorded in any patient.
Conclusion: PRF combined with RFT at high temperatures is an appropriate treatment option to prevent complications and shorten the regression time to side effects.

References

  • 1. Asplund P, Blomstedt P, Bergenheim AT. Percutaneous Balloon Compression vs Percutaneous Retrogasserian Glycerol Rhizotomy for the Primary Treatment of Trigeminal Neuralgia. Neurosurgery. 2016 Mar;78(3):421-8; discussion 428. doi: 10.1227/NEU.0000000000001059.
  • 2. Kanpolat Y, Savas A, Bekar A, Berk C. Percutaneous controlled radiofrequency trigeminal rhizotomy for the treatment of idiopathic trigeminal neuralgia: 25-year experience with 1,600 patients. Neurosurgery. 2001 Mar;48(3):524-32; discussion 532-4. doi: 10.1097/00006123-200103000-00013.
  • 3. Ding Y, Li H, Hong T, Zhu Y, Yao P, Zhou G. Combination of Pulsed Radiofrequency with Continuous Radiofrequency Thermocoagulation at Low Temperature Improves Efficacy and Safety in V2/V3 Primary Trigeminal Neuralgia. Pain Physician. 2018 Sep;21(5):E545-E553.
  • 4. Arıcı T, Kurcaloğlu M, Kılıç E, Erhan E. Radiofrequency thermocoagulation combined with pulsed radiofrequency for gasserian ganglion blockage. Agri. 2018 Oct;30(4):179-182. doi: 10.5505/agri.2018.88261.
  • 5. Hong T, Ding Y, Yao P. Long-Term Efficacy and Complications of Radiofrequency Thermocoagulation at Different Temperatures for the Treatment of Trigeminal Neuralgia. Biochem Res Int. 2020 Mar 4;2020:3854284. doi: 10.1155/2020/3854284.
  • 6. Tang YZ, Yang LQ, Yue JN, Wang XP, He LL, Ni JX. The optimal radiofrequency temperature in radiofrequency thermocoagulation for idiopathic trigeminal neuralgia: A cohort study. Medicine (Baltimore). 2016 Jul;95(28):e4103. doi: 10.1097/MD.0000000000004103.
  • 7. Yang JT, Lin M, Lee MH, Weng HH, Liao HH. Percutaneous trigeminal nerve radiofrequency rhizotomy guided by computerized tomography with three-dimensional image reconstruction. Chang Gung Med J. 2010 Nov-Dec;33(6):679-83.
  • 8. Fraioli MF, Cristino B, Moschettoni L, Cacciotti G, Fraioli C. Validity of percutaneous controlled radiofrequency thermocoagulation in the treatment of isolated third division trigeminal neuralgia. Surg Neurol. 2009 Feb;71(2):180-3. doi: 10.1016/j.surneu.2007.09.024.
  • 9. Kosugi S, Shiotani M, Otsuka Y, Suzuki T, Katori N, Hashiguchi S, Morisaki H. Long-term outcomes of percutaneous radiofrequency thermocoagulation of gasserian ganglion for 2nd- and multiple-division trigeminal neuralgia. Pain Pract. 2015 Mar;15(3):223-8. doi: 10.1111/papr.12163.
  • 10. Zheng S, Wu B, Zhao Y, Wang X, Li X, Yang L, He M, Yue J, Ni J. Masticatory Muscles Dysfunction after CT-guided Percutaneous Trigeminal Radiofrequency Thermocoagulation for Trigeminal Neuralgia: A Detailed Analysis. Pain Pract. 2015 Nov;15(8):712-9. doi: 10.1111/papr.12247.
  • 11. Fouad, W. Management of trigeminal neuralgia by radiofrequency thermocoagulation. Alexandria Journal of Medicine. 2011; 47(1), 79–86. https://doi.org/10.1016/j.ajme.2011.02.001.
  • 12. Koning MV, Koning NJ, Koning HM, van Kleef M. Relationship between Sensory Stimulation and Side Effects in Percutaneous Radiofrequency Treatment of the Trigeminal Ganglion. Pain Pract. 2014 Sep;14(7):581-7. doi: 10.1111/papr.12124.
  • 13. Yao P, Deng YY, Hong T, Wang ZB, Ma JM, Zhu YQ, Li HX, Ding YY, Pan SN. Radiofrequency thermocoagulation for V2/V3 idiopathic trigeminal neuralgia: effect of treatment temperatures on long-term clinical outcomes: A Cohort Study. Medicine (Baltimore). 2016 Jun;95(26):e4019. doi: 10.1097/MD.0000000000004019.
  • 14. Zhao WX, Wang Q, He MW, Yang LQ, Wu BS, Ni JX. Radiofrequency thermocoagulation combined with pulsed radiofrequency helps relieve postoperative complications of trigeminal neuralgia. Genet Mol Res. 2015 Jul 13;14(3):7616-23. doi: 10.4238/2015.July.13.5.
  • 15. Yao P, Hong T, Zhu YQ, Li HX, Wang ZB, Ding YY, Ma JM, Pan SN. Efficacy and safety of continuous radiofrequency thermocoagulation plus pulsed radiofrequency for treatment of V1 trigeminal neuralgia: A prospective cohort study. Medicine (Baltimore). 2016 Nov;95(44):e5247. doi: 10.1097/MD.0000000000005247. PMID: 27858881; PMCID: PMC5591129.
  • 16. Elawamy A, Abdalla EEM, Shehata GA. Effects of Pulsed Versus Conventional Versus Combined Radiofrequency for the Treatment of Trigeminal Neuralgia: A Prospective Study. Pain Physician. 2017 Sep;20(6):E873-E881. PMID: 28934792.
There are 16 citations in total.

Details

Primary Language English
Subjects Brain and Nerve Surgery (Neurosurgery), Pain, Neurology and Neuromuscular Diseases
Journal Section Research Article
Authors

Esra Ertilav 0009-0007-7926-1332

Öznur Yıldırım 0009-0004-3367-1414

Osman Nuri Aydın 0000-0002-5216-9962

Publication Date March 20, 2025
Submission Date November 22, 2024
Acceptance Date February 4, 2025
Published in Issue Year 2025 Volume: 26 Issue: 1

Cite

EndNote Ertilav E, Yıldırım Ö, Aydın ON (March 1, 2025) Comparison of Radiofrequency Thermocoagulation at High Temperatures with Combined Radiofrequency Thermocoagulation and Pulsed Radiofrequency in the Treatment of Trigeminal Neuralgia. Meandros Medical And Dental Journal 26 1 63–68.