The Value of Atherogenic Index of Plasma in Estimating Coronary Artery Calcium Scores

Year 2023, Volume: 24 Issue: 3, 247 - 252, 30.09.2023

Ahmet Lütfü Sertdemir , Ahmet Taha Şahin , Nergiz Aydın Mustafa Duran Abdullah İçli , Cengiz Kadıyoran , Pınar Diydem Yılmaz

Abstract

Objective: Coronary calcium load is a strong indicator of the presence and severity of atherosclerotic plaques in the coronary arteries. The atherogenic index of plasma (AIP) has been established for the evaluation of plasma atherogenicity and is strongly associated with an increased cardiovascular risk. Herein, we aimed to explore the compatibility of the risk groups determined by the coronary artery calcium (CAC) score and the risk groups predicted by the AIP.
Materials and Methods: The records of 173 patients who underwent cardiac computed tomography for suspected coronary artery disease between January 2019 and January 2022 were analyzed. Patients were divided into five groups based on calculated CAC cut-off values that have been commonly used in the literature.
Results: Regarding, calculated AIP levels, patients with severe CAC had significantly higher levels of AIP compared to other groups (p<0.001). To determine the AIP cut-off value to predict severe CAC, the receiver operating characteristic curve was drawn and the best cut-off value was determined as 0.60 by using the Youden index, (area under the curve: 0.774, 95% confidence interval: 0.685- 0.863, p<0.001). Above this threshold, CAC could be detected with a sensitivity of 75.8% and a specificity of 67.1%.
Conclusion: This study demonstrated that the AIP is an independent predictor of coronary calcification.

Keywords

Atherogenic index of plasma , coronary artery calcium score , computed tomography

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