Investigation of Clinical and Sociodemographic Characteristics of Critically Patients with COVID-19 Admitted to Intensive Care Unit

Yıl 2022, Cilt: 4 Sayı: 2, 141 - 7, 01.05.2022

Sabri Abuş Olga Bayar

https://doi.org/10.37990/medr.1019109

Öz

Aim: It is known that there is an increased risk of mortality due to COVID-19 in people with comorbid diseases. In this study, it was aimed to examine the comorbid diseases of patients treated in the intensive care unit due to COVID-19 and the effects of these diseases on mortality.
Material and Methods: In this study, the clinical and sociodemographic characteristics of 220 patients who were treated in the intensive care unit due to Covid-19 in a district state hospital between 01/06/2020-01/01/2021 were retrospectively analyzed.
Results: The mean age, urea, creatine, CRP, WBC, and neutrophil count were found to be significantly higher in the non-survivor group compared to the survivor group. Lymphocyte count, eosinophil count, HGB, and HCT were significantly higher in the survivor group. It was found that mortality was significantly increased in COVID-19 patients with DM, HT, CRF, COPD comorbid diseases.
Conclusion: According to the results we found, it is necessary to be more careful in the intensive care follow-up of COVID-19 patients with comorbid diseases such as DM, HT, COPD, CKD.

Anahtar Kelimeler

COVID-19, intensive care, hypertension, chronic kidney disease, diabetes mellitus

Yoğun Bakım Ünitesine Kabul Edilen COVID-19’lu Kritik Hastaların Klinik ve Sosyodemografik Özelliklerinin İncelenmesi

Öz

Amaç: Komorbid hastalıkları olan kişilerde COVID-19 nedeniyle mortalite riskinde artış olduğu bilinmektedir. Bu çalışmada COVID-19 nedeniyle yoğun bakım ünitesinde tedavi gören hastaların komorbid hastalıkları ve bu hastalıkların mortalite üzerindeki etkisinin incelenmesi amaçlanmıştır.
Materyal ve Metot: Bu çalışmada 01/06/2020-01/01/2021 tarihleri arasında bir ilçe devlet hastanesi’nde COVID-19 nedeniyle yoğun bakım ünitesinde tedavi gören 220 hastanın klinik ve sosyodemografik özellikleri retrospektif olarak incelenmiştir.
Bulgular: Yaş ortalaması, üre, kreatin, CRP, WBC ve nötrofil sayısı, yaşamını yitiren grupta, hayatta kalan gruba kıyasla anlamlı derecede yüksek bulundu. Hayatta kalan grupta lenfosit sayısı, eozinofil sayısı, HGB ve HCT anlamlı olarak daha yüksekti. DM, HT, KBY, KOAH komorbid hastalıkları olan COVID-19 hastalarında mortalitenin önemli ölçüde arttığı bulundu.
Sonuç: Bulduğumuz sonuçlara göre DM, HT, KOAH, KBY gibi komorbid hastalıkları olan COVID-19 hastalarının yoğun bakım takibinde daha dikkatli olunması gerekmektedir.

Anahtar Kelimeler

COVID-19, yoğun bakım, hipertansiyon, kronik böbrek hastalığı, diabetes mellitus

Kaynakça

• Jin Y, Yang H, Ji W, et al. Virology, epidemiology, pathogenesis, and control of COVID-19. Viruses. 2020;12: 372.
• Li H, Liu SM, Yu XH, et al. Coronavirus disease 2019 (COVID-19): current status and future perspectives. Int J Antimicrob Agents. 2020;55:105951.
• Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet. 2020;395:497-506.
• Murthy S, Gomersall CD, Fowler RA. Care for critically ill patients with COVID-19. Jama. 2020;323:1499-1500.
• https://www.who.int/publications-detail-redirect/WHO-2019-nCoV-clinical-2021-1
• Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese center for disease control and prevention. JAMA. 2020;323:1239–42,
• T.C. Sağlık Bakanlığı Bilimsel Danışma Kurulu Çalışması COVID-19 (SARS-CoV-2 ENFEKSİYONU) AĞIR PNÖMONİ, ARDS, SEPSİS VE SEPTİK ŞOK YÖNETİMİ 1 Haziran 2020, Ankara. https://covid19bilgi.saglik.gov.tr/depo/rehberler/covid19rehberi/COVID19_REHBERI_AGIR_PNOMONI_ARDS_SEPSIS_VE_SEPTIK_SOK_YONTEMI.pdf (29.03.2021).
• Mossa-Basha M, Meltzer CC, Kim DC, et al. Radiology department preparedness for COVID-19: radiology scientific expert review panel.2020.
• Yang X, Yu Y, Xu J, et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Resp Med. 2020;8:475-81.
• Grasselli G, Greco M, Zanella A, et al. Risk factors associated with mortality among patients with COVID-19 in intensive care units in Lombardy, Italy. JAMA Intern Med. 2020;180:1345-55.
• Mitra AR, Fergusson NA, Lloyd-Smith E, et al. Baseline characteristics and outcomes of patients with COVID-19 admitted to intensive care units in Vancouver, Canada: a case series. Cmaj. 2020;192:E694-E701.
• Guan WJ, jie Ni Z-yi, Hu Y, et al. Clinical characteristics of coronavirus disease, 2019;1708-20.
• Shi S, Qin M, Shen B, Cai, et al. Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China. JAMA cardiology. 2020;5:802-10.
• Chen T, Wu DI, Chen H, et al. Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study. Bmj. 2020;368.
• Schoen K, Horvat N, Guerreiro NF, et al. Spectrum of clinical and radiographic findings in patients with diagnosis of H1N1 and correlation with clinical severity. BMC Infecti Dis. 2019;19:1-8.
• Banik GR, Alqahtani AS, Booy R, et al. Risk factors for severity and mortality in patients with MERS-CoV: Analysis of publicly available data from Saudi Arabia. Virologica Sinica. 2016;31:81-4.
• Yang JK, Feng Y, Yuan MY, et al. Plasma glucose levels and diabetes are independent predictors for mortality and morbidity in patients with SARS. Diabet Med. 2006;23:623-8.
• Wu Z, & McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention. Jama. 2020; 323:1239-42.
• Onder G, Rezza G, & Brusaferro S. Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy. Jama. 2020;323:1775-6.
• Zhang JJ, Dong X, Cao YY, et al. Clinical characteristics of 140 patients infected with SARS‐CoV‐2 in Wuhan, China. Allergy. 2020;75:1730-41.
• Lippi G, & Plebani M. Laboratory abnormalities in patients with COVID-2019 infection. Clin Chem Lab Med (CCLM). 2020;58:1131-4.
• Lippi G, & Henry BM. Chronic obstructive pulmonary disease is associated with severe coronavirus disease 2019 (COVID-19). Respir Med. 2020;167:105941.
• Gold JA, Wong KK, Szablewski CM, et al. Characteristics and clinical outcomes of adult patients hospitalized with COVID-19—Georgia, March 2020. Morbidity and Mortality Weekly Report. 2020;69:545.
• Emami A, Javanmardi F, Pirbonyeh N, et al. Prevalence of underlying diseases in hospitalized patients with COVID-19: a systematic review and meta-analysis. Arch Acad Emerg Med. 2020;8.
• Chou CY, Wang SM, Liang CC, et al. Risk of pneumonia among patients with chronic kidney disease in outpatient and inpatient settings: a nationwide population-based study. Medicine. 2014; 93.
• Cascella M, Rajnik M, Aleem A, et al. Features, evaluation, and treatment of coronavirus (COVID-19). StatPearls. 2021.