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            <front>

                <journal-meta>
                                                                <journal-id>mersin univ saglık bilim derg</journal-id>
            <journal-title-group>
                                                                                    <journal-title>Mersin Üniversitesi Sağlık Bilimleri Dergisi</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">1308-0830</issn>
                                                                                            <publisher>
                    <publisher-name>Mersin Üniversitesi</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id/>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Public Health (Other)</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Halk Sağlığı (Diğer)</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <article-title>Akut Post-Streptokoksik Glomerülonefrit tanılı çocuk hastaların klinik özellikleri ve hastaların yapay zeka ile yeniden değerlendirilmesi</article-title>
                                                                                                                                                                                                <trans-title-group xml:lang="en">
                                    <trans-title>Clinical characteristics of pediatric patients diagnosed with Acute Post-Streptococcal Glomerulonephritis and re-evaluation of patients with artificial intelligence</trans-title>
                                </trans-title-group>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-0504-7911</contrib-id>
                                                                <name>
                                    <surname>Leventoğlu</surname>
                                    <given-names>Emre</given-names>
                                </name>
                                                                    <aff>Konya Şehir Hastanesi</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0001-9735-235X</contrib-id>
                                                                <name>
                                    <surname>Soran</surname>
                                    <given-names>Mustafa</given-names>
                                </name>
                                                                    <aff>Konya Şehir Hastanesi</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20240930">
                    <day>09</day>
                    <month>30</month>
                    <year>2024</year>
                </pub-date>
                                        <volume>17</volume>
                                        <issue>1 (özel sayı- MUSBD 2024; 17, özel sayı-1, 22. Mersin Pediatri Günleri Bildiri Kitabı)</issue>
                                        <fpage>162</fpage>
                                        <lpage>171</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20240803">
                        <day>08</day>
                        <month>03</month>
                        <year>2024</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20240818">
                        <day>08</day>
                        <month>18</month>
                        <year>2024</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 2008, Mersin Üniversitesi Sağlık Bilimleri Dergisi</copyright-statement>
                    <copyright-year>2008</copyright-year>
                    <copyright-holder>Mersin Üniversitesi Sağlık Bilimleri Dergisi</copyright-holder>
                </permissions>
            
                                                                                                <abstract><p>Amaç: Akut post-streptokokal glomerülonefrit (APSGN) çocuklar arasında akut glomerülonefritin önde gelen nedenidir. Akut nefritik sendrom, nefrotik sendrom ve hızlı ilerleyen glomerülonefrit şeklinde ortaya çıkabilir. ChatGPT (OpenAI, San Francisco, California, Amerika Birleşik Devletleri) yapay zeka destekli bir sohbet robotu olarak geliştirilmiştir. Bu çalışmada, yapay zekanın APSGN&#039;nin tanı, tedavi ve takibinde kullanılıp kullanılamayacağı ilk kez değerlendirilmiştir. Yöntem: APSGN tanısı alan hastaların klinik özellikleri hasta dosyalarından not edildi. APSGN hakkında genel bilgileri sorgulayan on iki soru ChatGPT 3.5&#039;e yöneltildi. Cevapların doğruluğu iki araştırmacı tarafından değerlendirildi. Daha sonra hastaların klinik ve laboratuvar özellikleri ChatGPT 3.5&#039;e aktarılarak hastaların takibinin yapay zeka tarafından nasıl yönetileceği incelendi. Bulgular: Çalışmaya toplam 11 hasta dahil edildi. Hastaların yaş ortalaması 9,08±3,96 yıldı. Sekiz (%72,7) hastada kreatinin yüksekliği ve 10 (%90,9) hastada hematüri ve/veya proteinüri vardı. ASO tüm hastalarda yüksek (955±353 IU/mL) ve C3 9 (%81,8) hastada düşüktü (0,56±0,34 g/L). Üç farklı hastada hipertansif ensefalopati, nefrotik sendrom ve hızlı ilerleyen glomerülonefrit gözlendi. Tüm hastalarda normal kreatinin değerlerine ulaşıldı. APSGN&#039;nin tanımı, epidemiyolojik özellikleri ve patofizyolojik mekanizmaları, tanı ve tedavisini değerlendiren sorular ChatGPT 3.5 tarafından doğru yanıtlandı. Ayrıca, tüm hastalara APSGN tanısı konmuş ve klinisyenler tarafından uygulanan tedavi adımları ChatGPT 3.5 tarafından benzer şekilde önerilmiştir. Sonuç: ChatGPT tarafından APSGN için sağlanan bilgi ve rehberlik, hastaların bakım ve yönetiminde değerli bir kaynak olabilir. Yapay zeka uygulamaları ile klinisyenler kararlarını gözden geçirebilir ve daha etkili tedavi planları oluşturabilirler.</p></abstract>
                                                                                                                                    <trans-abstract xml:lang="en">
                            <p>Objectives: Acute post-streptococcal glomerulonephritis (APSGN) is a leading cause of acute glomerulonephritis among children. It can present as acute nephritic syndrome, nephrotic syndrome, or rapidly progressive glomerulonephritis. ChatGPT (OpenAI, San Francisco, California, United States) is an artificial intelligence-powered chatbot. This study aimed to evaluate for the first time whether artificial intelligence can be used in the diagnosis, treatment, and follow-up of APSGN. Methods: Clinical characteristics of patients diagnosed with APSGN were noted from patient records. Twelve questions querying general information about APSGN were directed to ChatGPT 3.5. The accuracy of responses was evaluated by two researchers. Subsequently, clinical and laboratory features of patients were transferred to ChatGPT 3.5 to examine how the follow-up of patients could be managed by artificial intelligence. Results: A total of 11 patients were included in the study. The mean age of patients was 9.08±3.96 years. Eight (72.7%) patients had elevated creatinine levels, and 10 (90.9%) had hematuria and/or proteinuria. ASO was high in all patients (955±353 IU/mL), and C3 was low in 9 (81.8%) patients (0.56±0.34 g/L). Hypertensive encephalopathy, nephrotic syndrome, and rapidly progressive glomerulonephritis were observed in three different patients. Normal creatinine values were achieved in all patients. Questions evaluating the definition, epidemiological characteristics, pathophysiological mechanisms, diagnosis, and treatment of APSGN were correctly answered by ChatGPT 3.5. Additionally, APSGN diagnosis was made in all patients, and treatment steps applied by clinicians were similarly recommended by ChatGPT 3.5. Conclusion: The information and guidance provided by ChatGPT for APSGN could be a valuable resource in patient care and management. With artificial intelligence applications, clinicians can review their decisions and create more effective treatment plans.</p></trans-abstract>
                                                            
            
                                                            <kwd-group>
                                                    <kwd>Akut postenfeksiyon glomerülonefrit</kwd>
                                                    <kwd>  Yapay zeka</kwd>
                                                    <kwd>  ChatGPT</kwd>
                                            </kwd-group>
                                                        
                                                                            <kwd-group xml:lang="en">
                                                    <kwd>Acute post-infection glomerulonephritis</kwd>
                                                    <kwd>  Artificial intelligence</kwd>
                                                    <kwd>  ChatGPT</kwd>
                                            </kwd-group>
                                                                                                            </article-meta>
    </front>
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                            <ref-list>
                                    <ref id="ref1">
                        <label>1</label>
                        <mixed-citation publication-type="journal">Steer AC, Danchin MH, Carapetis JR. Group A streptococcal infections in children. J Paediatr Child Health 2007;43:203–213.</mixed-citation>
                    </ref>
                                    <ref id="ref2">
                        <label>2</label>
                        <mixed-citation publication-type="journal">Balasubramanian R, Marks SD. Post-infectious ğlomerulonephritis. Paediatr Int Child Health 2017;37:240–247.</mixed-citation>
                    </ref>
                                    <ref id="ref3">
                        <label>3</label>
                        <mixed-citation publication-type="journal">Rodriğuez-Iturbe B, Musser JM. The current state of poststreptococcal ğlomerulonephritis. J Am Soc Nephrol 2008;19:1855–1864.</mixed-citation>
                    </ref>
                            </ref-list>
                    </back>
    </article>
