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            <front>

                <journal-meta>
                                                                <journal-id>med j west black sea</journal-id>
            <journal-title-group>
                                                                                    <journal-title>Medical Journal of Western Black Sea</journal-title>
            </journal-title-group>
                            <issn pub-type="ppub">2822-4302</issn>
                                        <issn pub-type="epub">2587-0602</issn>
                                                                                            <publisher>
                    <publisher-name>Zonguldak Bülent Ecevit Üniversitesi</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id pub-id-type="doi">10.29058/mjwbs.1267521</article-id>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Health Care Administration</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Sağlık Kurumları Yönetimi</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <trans-title-group xml:lang="tr">
                                    <trans-title>Herpes Zoster Tanısı Alan İmmünkompetan Hastaların Epidemiyolojik ve Klinik Özellikleri: Sinop İlinden Tek Merkezli Retrospektif Kohort Çalışma</trans-title>
                                </trans-title-group>
                                                                                                                                                                                                <article-title>Clinico-Epidemiological Profile of Immunocompetent Patients Diagnosed with Herpes Zoster: A Single-Center Retrospective Cohort Study from Sinop</article-title>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-2982-3823</contrib-id>
                                                                <name>
                                    <surname>Keskinkaya</surname>
                                    <given-names>Zeynep</given-names>
                                </name>
                                                                    <aff>ÇANAKKALE ONSEKİZ MART ÜNİVERSİTESİ, TIP FAKÜLTESİ</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-0304-491X</contrib-id>
                                                                <name>
                                    <surname>Sariyeva Ismayilov</surname>
                                    <given-names>Ayna</given-names>
                                </name>
                                                                    <aff>SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, BURSA YÜKSEK İHTİSAS SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ, GÖZ HASTALIKLARI ANABİLİM DALI</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0003-1005-3205</contrib-id>
                                                                <name>
                                    <surname>Aydın Güçlü</surname>
                                    <given-names>Özge</given-names>
                                </name>
                                                                    <aff>BURSA ULUDAĞ ÜNİVERSİTESİ, TIP FAKÜLTESİ</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20230831">
                    <day>08</day>
                    <month>31</month>
                    <year>2023</year>
                </pub-date>
                                        <volume>7</volume>
                                        <issue>2</issue>
                                        <fpage>120</fpage>
                                        <lpage>127</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20230320">
                        <day>03</day>
                        <month>20</month>
                        <year>2023</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20230806">
                        <day>08</day>
                        <month>06</month>
                        <year>2023</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 2017, Batı Karadeniz Tıp Dergisi</copyright-statement>
                    <copyright-year>2017</copyright-year>
                    <copyright-holder>Batı Karadeniz Tıp Dergisi</copyright-holder>
                </permissions>
            
                                                                                                <trans-abstract xml:lang="tr">
                            <p>Amaç: İmmünsupresyon herpes zoster (HZ) için iyi bilinen bir risk faktörü olsa da, bu tablo genellikleimmünkompetan olgularda görülür. Bu çalışmada immünkompetan HZ olgularında demografik ve kliniközelliklerin, HZ gelişimine neden olan faktörlerin ve HZ ile ilişkili komplikasyonların değerlendirilmesiamaçlanmıştır.Gereç ve Yöntemler: Bu tek merkezli retrospektif kohort çalışmaya, Eylül 2019 ve Ağustos 2020 tarihleri arasında HZ tanısı alan 103hasta arasından bilinen immünsupresif durumu olmayan 98 hasta dahil edilmiştir. Hastalar yaş, cinsiyet, tıbbi özgeçmiş, klinik bulgular,tetikleyici faktörler, tanı aldıkları mevsim, komplikasyonlar ve sistemik inflamasyon göstergesi olarak nötrofil lenfosit oranı (NLO) açısındandeğerlendirilmiştir.Bulgular: Ortanca yaşı 59 olan (yaş aralığı: 5-88) 98 immünkompetan hasta (erkek:kadın oranı=1,1:1) HZ tanısı almıştı. En sık tutulandermatom torakal dermatomdu (n=45). Trigeminal sinir tutulumu olan 11 hastanın sekizinde oftalmik HZ mevcuttu. HZ atakları sıklıkla yazdöneminde görülürken tüm oftalmik HZ olguları sonbahar ve kış mevsimlerinde tanı almıştı. İki olguda travma sonrası oftalmik HZ görülmüştü.Takipte erkek cinsiyet baskın olmak üzere 11 hastada postherpetik nevralji (PHN) gelişmişti (p=0,009). İstatistiksel olarak anlamlı olmamaklabirlikte (p=0,136), PHN gelişen hastalarda ortalama NLO değeri daha yüksekti.Sonuç: Çalışmamızdaki bulgular, HZ&#039;nin ana prezentasyon paterni olan tek taraflı torakal dermatom tutulumu ve bir grup hastada ortayaçıkan PHN ve oftalmik HZ gibi komplikasyonlar açısından mevcut literatür ile uyumludur. Serimizdeki yüksek HZ insidans oranı, muhtemelenbölgemizdeki popülasyonun ortanca yaşının yüksek olmasından kaynaklanmaktadır. HZ olgularının yaz döneminde artış göstermesiultraviyole ışınlarına bağlı mevsimsel etkiyi desteklerken, mekanik travma başka bir olası tetikleyici faktördür. NLO&#039;nun PHN açısındanprediktif değeri ileri çalışmalarla değerlendirilmelidir.</p></trans-abstract>
                                                                                                                                    <abstract><p>Aim: Herpes zoster (HZ) mainly occurs in immunocompetent individuals, even though immunosuppressionis a well-known risk factor. The aim of this study was to evaluate the demographic and clinical featuresof immunocompetent HZ patients and HZ-related complications with a special focus on possiblecontributing factors.Material and Methods: This single-center, retrospective cohort study included 98 patients with noknown immunosuppressive condition out of 103 patients diagnosed with HZ between September 2019and August 2020. The patients were evaluated in terms of age, sex, medical history, clinical features,triggering factors, seasonality, complications, and neutrophil-to-lymphocyte ratio (NLR) as a marker ofsystemic inflammation.Results: Ninetyeight immunocompetent patients (male:female ratio=1.1:1) were diagnosed with HZ,with a median age of 59 years (age range: 5-88). Thoracic dermatome was the leading dermatome(n=45). Trigeminal nerve was involved in 11 patients, eight of them presenting with ophthalmic HZ. HZattacks were mainly detected in summer, while ophthalmic HZ cases were exclusively diagnosed duringfall and winter. Two patients developed ophthalmic HZ following trauma. Eleven patients experiencedpostherpetic neuralgia (PHN) during follow-up with a male predominance (p=0.009). A higher mean NLRvalue was detected in PHN patients, although it was not statistically significant (p=0.136).Conclusion: The findings of our study are compatible with the current literature regarding the mainpresentation pattern of HZ as unilateral thoracic dermatome involvement and the complications such asPHN and ophthalmic HZ occurring in a subgroup of patients. The high HZ incidence rate in our series islikely due to the high median age of the population in our region. The summer peak of HZ cases furthersupports the seasonal variability due to the ultraviolet effect, whereas mechanical trauma is anotherpossible triggering factor. The predictive value of NLR for PHN should be evaluated in further studies.</p></abstract>
                                                            
            
                                                                                        <kwd-group>
                                                    <kwd>Herpes zoster</kwd>
                                                    <kwd>  immunocompetent</kwd>
                                                    <kwd>  postherpetic neuralgia</kwd>
                                                    <kwd>  ophthalmic herpes zoster</kwd>
                                                    <kwd>  neutrophil-to-lymphocyte ratio</kwd>
                                            </kwd-group>
                            
                                                <kwd-group xml:lang="tr">
                                                    <kwd>Herpes zoster</kwd>
                                                    <kwd>  immünkompetan</kwd>
                                                    <kwd>  postherpetik nevralji</kwd>
                                                    <kwd>  oftalmik herpes zoster</kwd>
                                                    <kwd>  nötrofil lenfosit oranı</kwd>
                                            </kwd-group>
                                                                                                                                        </article-meta>
    </front>
    <back>
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