Research Article

A comprehensive study of monkeypox disease through fractional mathematical modeling

Volume: 5 Number: 1 March 31, 2025
EN

A comprehensive study of monkeypox disease through fractional mathematical modeling

Abstract

This research investigates a fractional-order mathematical model for analyzing the dynamics of Monkeypox (Mpox) disease using the Caputo-Fabrizio derivative. The model incorporates both human and rodent populations, aiming to elucidate the disease's transmission mechanics, which is demonstrated to be more effective than integer-order models in capturing the complex nature of disease spread. The study determines the fundamental reproduction number ($R_{0}$) while assessing the existence and uniqueness of the solutions. Numerical simulations are conducted to validate the model using Adams-Bashforth technique and illustrate the influence of different factors on the progression of the disease. The findings shed light on Mpox control and prevention, emphasizing the importance of fractional calculus in epidemiological modeling.

Keywords

Adams-Bashforth technique, Caputo-Fabrizio derivative, existence and uniqueness, fixed point theorem, monkeypox virus

Ethical Statement

The authors state that this research complies with ethical standards. This research does not involve either human participants or animals.

References

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APA
Manivel, M., Venkatesh, A., & Kumawat, S. (2025). A comprehensive study of monkeypox disease through fractional mathematical modeling. Mathematical Modelling and Numerical Simulation With Applications, 5(1), 65-96. https://doi.org/10.53391/mmnsa.1571609
AMA
1.Manivel M, Venkatesh A, Kumawat S. A comprehensive study of monkeypox disease through fractional mathematical modeling. MMNSA. 2025;5(1):65-96. doi:10.53391/mmnsa.1571609
Chicago
Manivel, M., A. Venkatesh, and Shyamsunder Kumawat. 2025. “A Comprehensive Study of Monkeypox Disease through Fractional Mathematical Modeling”. Mathematical Modelling and Numerical Simulation With Applications 5 (1): 65-96. https://doi.org/10.53391/mmnsa.1571609.
EndNote
Manivel M, Venkatesh A, Kumawat S (March 1, 2025) A comprehensive study of monkeypox disease through fractional mathematical modeling. Mathematical Modelling and Numerical Simulation with Applications 5 1 65–96.
IEEE
[1]M. Manivel, A. Venkatesh, and S. Kumawat, “A comprehensive study of monkeypox disease through fractional mathematical modeling”, MMNSA, vol. 5, no. 1, pp. 65–96, Mar. 2025, doi: 10.53391/mmnsa.1571609.
ISNAD
Manivel, M. - Venkatesh, A. - Kumawat, Shyamsunder. “A Comprehensive Study of Monkeypox Disease through Fractional Mathematical Modeling”. Mathematical Modelling and Numerical Simulation with Applications 5/1 (March 1, 2025): 65-96. https://doi.org/10.53391/mmnsa.1571609.
JAMA
1.Manivel M, Venkatesh A, Kumawat S. A comprehensive study of monkeypox disease through fractional mathematical modeling. MMNSA. 2025;5:65–96.
MLA
Manivel, M., et al. “A Comprehensive Study of Monkeypox Disease through Fractional Mathematical Modeling”. Mathematical Modelling and Numerical Simulation With Applications, vol. 5, no. 1, Mar. 2025, pp. 65-96, doi:10.53391/mmnsa.1571609.
Vancouver
1.M. Manivel, A. Venkatesh, Shyamsunder Kumawat. A comprehensive study of monkeypox disease through fractional mathematical modeling. MMNSA. 2025 Mar. 1;5(1):65-96. doi:10.53391/mmnsa.1571609