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Coincident Pelvic Uptake in the F-18 FDG PET/CT Imaging in Patients With the Diagnosis of Breast Carcinoma

Yıl 2022, Cilt: 2 Sayı: 2, 6 - 11, 01.08.2022

Öz

Objective: The F-18 FDG PET/CT imaging is a commonly preferred imaging modality for staging breast carcinoma. The gynecological tumors are more frequently present in patients with breast carcinoma compared to the general population. The aim of this study was to investigate the clinical importance of the uterine and adnexal uptake observed incidentally in the F-18 FDG PET/CT imaging of breast carcinoma.
Patients and Methods: The F-18 FDG PET/CT images (performed for staging or treatment response evaluation purposes) of the patients (sixty-six women, the mean age 49,5±12,6 years) with suspicious uterine and/or adnexal uptake were included in the study. The imaging results were compared with pelvic examination data as well as operative and pathology results.
Results: In the imaging studies the increased FDG uptake sites were the primary tumor (mean 27, 3 (24,5) mm, SUVmax=31,3 (20) in 35 patients, and 22 patients additional axillar metastases and distant metastasis in 19 patient were observed. Among the patients involved in the study 29 had unilateral adnexal uptake and/or lesion and/or uterine uptake and others had suspicious findings without increased uptake.
Conclusion: Referral of the patients for gynecological examination with coincident uterine and adnexal abnormal uptake in the F-18 FDG PET/CT would be the appropriate approach for the patients with the diagnosis of breast cancer.

Kaynakça

  • 1. Ishimori, T., Patel, P. V., & Wahl, R. L. (2005). Detection of unexpected additional primary malignancies with PET/CT. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 46(5), 752–757.
  • 2. Agress, H., Jr, & Cooper, B. Z. (2004). Detection of clinically unexpected malignant and premalignant tumors with whole-body FDG PET: histopathologic comparison. Radiology, 230(2), 417–422. https://doi.org/10.1148/radiol.2302021685
  • 3. Wooster, R., & Weber, B. L. (2003). Breast and ovarian cancer. The New England journal of medicine, 348(23), 2339–2347. https://doi.org/10.1056/NEJMra012284
  • 4. Lerman H, Metser U, Grisaru D, Fishman A, Lievshitz G, Even-Sapir E. Normal and abnormal 18F-FDG endometrial and ovarian uptake in pre- and postmenopausal patients: assessment by PET/CT. J Nucl Med. 2004;45:266–71.
  • 5. Park, S. A., Lee, K. M., Choi, U., Kim, H. S., Kim, H. W., & Song, J. H. (2010). Normal Physiologic and Benign Foci with F-18 FDG Avidity on PET/CT in Patients with Breast Cancer. Nuclear medicine and molecular imaging, 44(4), 282–289. https://doi.org/10.1007/s13139-010-0055-7
  • 6. Razia, S., Nakayama, K., Tsukao, M., Nakamura, K., Ishikawa, M., Ishibashi, T., Ishikawa, N., Sanuki, K., Yamashita, H., Ono, R., Hossain, M. M., Minamoto, T., & Kyo, S. (2017). Metastasis of breast cancer to an endometrial polyp, the cervix and a leiomyoma: A case report and review of the literature. Oncology letters, 14(4), 4585–4592. https://doi.org/10.3892/ol.2017.6822
  • 7. Akhtar, A., Ratra, A., Puckett, Y., Sheikh, A. B., & Ronaghan, C. A. (2017). Synchronous Uterine Metastases from Breast Cancer: Case Study and Literature Review. Cureus, 9(11), e1840. https://doi.org/10.7759/cureus.1840
  • 8. Abrams HL, Spiro R and Goldstein N. Metastases in carcinoma: Analysis of 1000 autopside cases. Cancer 1950;3:74-85
  • 9. Lee, J. W., Lee, J. H., Cho, A., Yun, M., Lee, J. D., Kim, Y. T., & Kang, W. J. (2015). The performance of contrast-enhanced FDG PET/CT for the differential diagnosis of unexpected ovarian mass lesions in patients with nongynecologic cancer. Clinical nuclear medicine, 40(2), 97–102. https://doi.org/10.1097/RLU.0000000000000667
  • 10. Jeffry, L., Kerrou, K., Camatte, S., Metzger, U., Lelièvre, L., Talbot, J. N., & Lecuru, F. (2004). Endometriosis with FDG uptake on PET. European journal of obstetrics, gynecology, and reproductive biology, 117(2), 236–239. https://doi.org/10.1016/j.ejogrb.2004.04.034
  • 11. Ames, J., Blodgett, T., & Meltzer, C. (2005). 18F-FDG uptake in an ovary containing a hemorrhagic corpus luteal cyst: false-positive PET/CT in a patient with cervical carcinoma. AJR. American journal of roentgenology, 185(4), 1057–1059. https://doi.org/10.2214/AJR.04.1282
  • 12. Su, H. M., Hu, C., Tsay, D. G., & Peng, N. J. (2011). Ovarian thecoma mimicking carcinoma on F-18 FDG PET in a postmenopausal woman with elevated CA-125. Clinical nuclear medicine, 36(12), 1133–1134. https://doi.org/10.1097/RLU.0b013e3182335e57
  • 13. Takeda, T., Sagae, S., Koizumi, M., Terasawa, K., Ishioka, S., Takashima, S., & Kudo, R. (1995). Multiple primary malignancies in patients with gynecologic cancer. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 5(1), 34–39. https://doi.org/10.1046/j.1525-1438.1995.05010034.x
  • 14. Babacan, N. A., Aksoy, S., Cetin, B., Ozdemir, N. Y., Benekli, M., Uyeturk, U., Ali Kaplan, M., Kos, T., Karaca, H., Oksuzoglu, B., Zengin, N., & Buyukberber, S. (2012). Multiple primary malignant neoplasms: multi-center results from Turkey. Journal of B.U.ON. : official journal of the Balkan Union of Oncology, 17(4), 770–775
  • 15. Plotcha M, Cholewinski W, Buchardt E, Cegla P, Urbanski B, Warenczok-Florczak Z, et al. Strategy and early results of treatment of advanced cervical cancer. Gynocologica Polska 2017;88:475-80.
Yıl 2022, Cilt: 2 Sayı: 2, 6 - 11, 01.08.2022

Öz

Kaynakça

  • 1. Ishimori, T., Patel, P. V., & Wahl, R. L. (2005). Detection of unexpected additional primary malignancies with PET/CT. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 46(5), 752–757.
  • 2. Agress, H., Jr, & Cooper, B. Z. (2004). Detection of clinically unexpected malignant and premalignant tumors with whole-body FDG PET: histopathologic comparison. Radiology, 230(2), 417–422. https://doi.org/10.1148/radiol.2302021685
  • 3. Wooster, R., & Weber, B. L. (2003). Breast and ovarian cancer. The New England journal of medicine, 348(23), 2339–2347. https://doi.org/10.1056/NEJMra012284
  • 4. Lerman H, Metser U, Grisaru D, Fishman A, Lievshitz G, Even-Sapir E. Normal and abnormal 18F-FDG endometrial and ovarian uptake in pre- and postmenopausal patients: assessment by PET/CT. J Nucl Med. 2004;45:266–71.
  • 5. Park, S. A., Lee, K. M., Choi, U., Kim, H. S., Kim, H. W., & Song, J. H. (2010). Normal Physiologic and Benign Foci with F-18 FDG Avidity on PET/CT in Patients with Breast Cancer. Nuclear medicine and molecular imaging, 44(4), 282–289. https://doi.org/10.1007/s13139-010-0055-7
  • 6. Razia, S., Nakayama, K., Tsukao, M., Nakamura, K., Ishikawa, M., Ishibashi, T., Ishikawa, N., Sanuki, K., Yamashita, H., Ono, R., Hossain, M. M., Minamoto, T., & Kyo, S. (2017). Metastasis of breast cancer to an endometrial polyp, the cervix and a leiomyoma: A case report and review of the literature. Oncology letters, 14(4), 4585–4592. https://doi.org/10.3892/ol.2017.6822
  • 7. Akhtar, A., Ratra, A., Puckett, Y., Sheikh, A. B., & Ronaghan, C. A. (2017). Synchronous Uterine Metastases from Breast Cancer: Case Study and Literature Review. Cureus, 9(11), e1840. https://doi.org/10.7759/cureus.1840
  • 8. Abrams HL, Spiro R and Goldstein N. Metastases in carcinoma: Analysis of 1000 autopside cases. Cancer 1950;3:74-85
  • 9. Lee, J. W., Lee, J. H., Cho, A., Yun, M., Lee, J. D., Kim, Y. T., & Kang, W. J. (2015). The performance of contrast-enhanced FDG PET/CT for the differential diagnosis of unexpected ovarian mass lesions in patients with nongynecologic cancer. Clinical nuclear medicine, 40(2), 97–102. https://doi.org/10.1097/RLU.0000000000000667
  • 10. Jeffry, L., Kerrou, K., Camatte, S., Metzger, U., Lelièvre, L., Talbot, J. N., & Lecuru, F. (2004). Endometriosis with FDG uptake on PET. European journal of obstetrics, gynecology, and reproductive biology, 117(2), 236–239. https://doi.org/10.1016/j.ejogrb.2004.04.034
  • 11. Ames, J., Blodgett, T., & Meltzer, C. (2005). 18F-FDG uptake in an ovary containing a hemorrhagic corpus luteal cyst: false-positive PET/CT in a patient with cervical carcinoma. AJR. American journal of roentgenology, 185(4), 1057–1059. https://doi.org/10.2214/AJR.04.1282
  • 12. Su, H. M., Hu, C., Tsay, D. G., & Peng, N. J. (2011). Ovarian thecoma mimicking carcinoma on F-18 FDG PET in a postmenopausal woman with elevated CA-125. Clinical nuclear medicine, 36(12), 1133–1134. https://doi.org/10.1097/RLU.0b013e3182335e57
  • 13. Takeda, T., Sagae, S., Koizumi, M., Terasawa, K., Ishioka, S., Takashima, S., & Kudo, R. (1995). Multiple primary malignancies in patients with gynecologic cancer. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 5(1), 34–39. https://doi.org/10.1046/j.1525-1438.1995.05010034.x
  • 14. Babacan, N. A., Aksoy, S., Cetin, B., Ozdemir, N. Y., Benekli, M., Uyeturk, U., Ali Kaplan, M., Kos, T., Karaca, H., Oksuzoglu, B., Zengin, N., & Buyukberber, S. (2012). Multiple primary malignant neoplasms: multi-center results from Turkey. Journal of B.U.ON. : official journal of the Balkan Union of Oncology, 17(4), 770–775
  • 15. Plotcha M, Cholewinski W, Buchardt E, Cegla P, Urbanski B, Warenczok-Florczak Z, et al. Strategy and early results of treatment of advanced cervical cancer. Gynocologica Polska 2017;88:475-80.
Toplam 15 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Onkoloji ve Karsinogenez
Bölüm Case Reports
Yazarlar

Zehra Pınar Koç Bu kişi benim 0000-0002-3274-5790

Pınar Pelin Özcan Bu kişi benim 0000-0003-0147-2678

Emel Sezer Bu kişi benim 0000-0001-9881-3533

Ahmet Dağ Bu kişi benim 0000-0002-1120-3773

Ferah Tuncel Daloğlu Bu kişi benim 0000-0001-6506-9461

Tolgay Tuyan İlhan Bu kişi benim 0000-0002-2186-441X

Yayımlanma Tarihi 1 Ağustos 2022
Yayımlandığı Sayı Yıl 2022 Cilt: 2 Sayı: 2

Kaynak Göster

APA Koç, Z. P., Özcan, P. P., Sezer, E., Dağ, A., vd. (2022). Coincident Pelvic Uptake in the F-18 FDG PET/CT Imaging in Patients With the Diagnosis of Breast Carcinoma. Molecular Oncologic Imaging, 2(2), 6-11.
AMA Koç ZP, Özcan PP, Sezer E, Dağ A, Tuncel Daloğlu F, İlhan TT. Coincident Pelvic Uptake in the F-18 FDG PET/CT Imaging in Patients With the Diagnosis of Breast Carcinoma. Molecular Oncologic Imaging. Ağustos 2022;2(2):6-11.
Chicago Koç, Zehra Pınar, Pınar Pelin Özcan, Emel Sezer, Ahmet Dağ, Ferah Tuncel Daloğlu, ve Tolgay Tuyan İlhan. “Coincident Pelvic Uptake in the F-18 FDG PET/CT Imaging in Patients With the Diagnosis of Breast Carcinoma”. Molecular Oncologic Imaging 2, sy. 2 (Ağustos 2022): 6-11.
EndNote Koç ZP, Özcan PP, Sezer E, Dağ A, Tuncel Daloğlu F, İlhan TT (01 Ağustos 2022) Coincident Pelvic Uptake in the F-18 FDG PET/CT Imaging in Patients With the Diagnosis of Breast Carcinoma. Molecular Oncologic Imaging 2 2 6–11.
IEEE Z. P. Koç, P. P. Özcan, E. Sezer, A. Dağ, F. Tuncel Daloğlu, ve T. T. İlhan, “Coincident Pelvic Uptake in the F-18 FDG PET/CT Imaging in Patients With the Diagnosis of Breast Carcinoma”, Molecular Oncologic Imaging, c. 2, sy. 2, ss. 6–11, 2022.
ISNAD Koç, Zehra Pınar vd. “Coincident Pelvic Uptake in the F-18 FDG PET/CT Imaging in Patients With the Diagnosis of Breast Carcinoma”. Molecular Oncologic Imaging 2/2 (Ağustos 2022), 6-11.
JAMA Koç ZP, Özcan PP, Sezer E, Dağ A, Tuncel Daloğlu F, İlhan TT. Coincident Pelvic Uptake in the F-18 FDG PET/CT Imaging in Patients With the Diagnosis of Breast Carcinoma. Molecular Oncologic Imaging. 2022;2:6–11.
MLA Koç, Zehra Pınar vd. “Coincident Pelvic Uptake in the F-18 FDG PET/CT Imaging in Patients With the Diagnosis of Breast Carcinoma”. Molecular Oncologic Imaging, c. 2, sy. 2, 2022, ss. 6-11.
Vancouver Koç ZP, Özcan PP, Sezer E, Dağ A, Tuncel Daloğlu F, İlhan TT. Coincident Pelvic Uptake in the F-18 FDG PET/CT Imaging in Patients With the Diagnosis of Breast Carcinoma. Molecular Oncologic Imaging. 2022;2(2):6-11.