Renal Metastasis of Primary Lung Carcinoma is Associated with Death and Progression Predicted by F-18 FDG PET/CT

Year 2023, Volume: 3 Issue: 1, 7 - 12, 20.04.2023

Zehra Pınar Koç , Pelin Özcan Kara , Vehbi Erçolak Yasemin Yuyucu Karabulut

Abstract

Aim: The renal metastasis of primary lung carcinoma is not infrequent. However, the imaging modalities usually underestimate this important finding. The aim of this study was to firstly to investigate the imaging and follow up findings associated with renal metastasis of a primary lung carcinoma in F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (FDG PET/CT) and secondly underline the importance of this finding that usually is not detected with imaging methods.
Materials and Methods: The F-18 FDG PET/CT images of 17 patients (1 F, 16 M; mean: 61,6±9,3 years old) with renal metastasis of the primary lung carcinoma were evaluated retrospectively. The findings were compared with gold standard patients oncologic follow up.
Results: The renal lesions maximum dimensions were mean: 40,7±25,7 mm and SUVmax level was mean: 17,1±6,5. The lesions of the patients were confirmed with CT and US imaging and pathology results in six patients which of one patient underwent nephrectomy. Six of 17 patients died and others were diagnosed as progressive metastatic disease during the follow up period (mean: 6,4±6,6 months).
Conclusion: In this series the renal metastasis of lung carcinoma was associated with progressive disease or death in the follow up. Further studies with long term follow up in larger series are warranted.

Keywords

kidney, metastasis, lung carcinoma, FDG, PET

Project Number

2021/352

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