Background: The chest wall tumors are rare lesions thus there are limited literature data about the radiologic appearance of these tumors and no previous study exists about the diagnostic performance of the functional imaging modalities. Aim of this study is to analyze the diagnostic accuracy of the hybrid imaging modalities: Single photon emission computed tomography/computed tomography (SPECT/CT) and Positron emission tomography/computed tomography (PET/CT) in comparison to the histopathology results of the chest wall tumors.
Materials and Methods: Imaging results of the patients (n=20, 7F/13M, mean: 53±21,9 years of age) with the diagnosis of chest wall mass were recorded. Retrospective evaluation of the images were performed by an experienced Nuclear Medicine physician and compared with the histopathology results as gold standard.
Results: The lesions of the patients that were involved in this study were mean: 63±33.8 mm and the standardized uptake value (SUVmax) were mean: 13.7±10.8. The imaging/metabolic characteristics of the lesions were considered malign in all the patients included. All the patients diagnosed to have malign neoplasms except two.
Conclusion: The hybrid imaging has excellent diagnostic facility in diagnosis of the chest wall neoplasm. Prospective studies about this issue are warranted.
Ethics approval was obtained, consent to participate obtained, consent for publication
obtained, availability of data and material provided, competing interests;nothing to disclose,
funding; none provided, authors' contributions; sufficently participated, acknowledgements;
none.
References
Ilgan, S., Dikmen, E., Cetinkanat, C. G., Dakak, M., & Güngör, A. (2014). Schwannomatozis of the Chest Wall: FDG PET Findings. Molecular imaging and radionuclide therapy, 23(2), 64–66. https://doi.org/10.4274/mirt.353
Chadaz, T., Hobbs, S. K., & Son, H. (2013). Chest wall sarcoma: 18F-FDG PET/CT in a patient with Li-Fraumeni syndrome. Clinical nuclear medicine, 38(10), 818–820. https://doi.org/10.1097/RLU.0b013e3182a20033
Carter, B. W., Benveniste, M. F., Betancourt, S. L., de Groot, P. M., Lichtenberger, J. P., 3rd, Amini, B., & Abbott, G. F. (2016). Imaging Evaluation of Malignant Chest Wall Neoplasms. Radiographics : a review
Molecular Oncologic Imaging 2023;3(3):01-07 7 publication of the Radiological Society of North America, Inc, 36(5), 1285–1306. https://doi.org/10.1148/rg.2016150208
Jiang, L., Gao, Y., Sheng, S., Xu, M., Lu, L., & Lu, H. (2011). A first described chest wall metastasis from colon cancer demonstrated with (18)F-FDG PET/CT. Hellenic journal of nuclear medicine, 14(3), 316–317.
David, E. A., & Marshall, M. B. (2011). Review of chest wall tumors: a diagnostic, therapeutic, and reconstructive challenge. Seminars in plastic surgery, 25(1), 16–24. https://doi.org/10.1055/s-0031-1275167
Mullan, C. P., Madan, R., Trotman-Dickenson, B., Qian, X., Jacobson, F. L., & Hunsaker, A. (2011). Radiology of chest wall masses. AJR. American journal of roentgenology, 197(3), W460–W470. https://doi.org/10.2214/AJR.10.7259
Bandi, V., Lunn, W., Ernst, A., Eberhardt, R., Hoffmann, H., & Herth, F. J. (2008). Ultrasound vs. CT in detecting chest wall invasion by tumor: a prospective study. Chest, 133(4), 881–886. https://doi.org/10.1378/chest.07-1656
Cohen, L. M., Schwartz, A. M., & Rockoff, S. D. (1986). Benign schwannomas: pathologic basis for CT inhomogeneities. AJR. American journal of roentgenology, 147(1), 141–143. https://doi.org/10.2214/ajr.147.1.141
O'Sullivan, P., O'Dwyer, H., Flint, J., Munk, P. L., & Muller, N. (2007). Soft tissue tumours and mass-like lesions of the chest wall: a pictorial review of CT and MR findings. The British journal of radiology, 80(955), 574–580. https://doi.org/10.1259/bjr/16591964
Cheng, G., Newberg, A. B., & Alavi, A. (2011). Metastatic melanoma causing complete atrioventricular block--the role of FDG PET/CT in diagnosis. Clinical imaging, 35(4), 312–314. https://doi.org/10.1016/j.clinimag.2010.08.008
Halac, M., Cnaral, F., Sait, S., Ylmaz, S., Kerim, S., Sergülen, D., & Uslu, I. (2008). FDG PET/CT findings in recurrent malignant schwannoma. Clinical nuclear medicine, 33(3), 172–174. https://doi.org/10.1097/RLU.0b013e318162d922
Wasyliw, C. W., & Caride, V. J. (2005). Incidental detection of bilateral elastofibroma dorsi with F-18 FDG PET/CT. Clinical nuclear medicine, 30(10), 700–701. https://doi.org/10.1097/01.rlu.0000178786.99368.1d
Okamoto, K., Tani, Y., Yamaguchi, T., Ogino, K., Tsuchioka, T., Nakajima, M., Yamaguchi, S., Sasaki, K., Kato, H., & Ohya, T. (2015). Asymptomatic Mesenchymal Hamartoma of the Chest Wall in Child With Fluorodeoxyglucose Uptake on PET/CT-Report of a Case. International surgery, 100(5), 915–919. https://doi.org/10.9738/INTSURG-D-14-00083.1
Yeom, Y. K., Kim, M. Y., Lee, H. J., & Kim, S. S. (2015). Solitary Fibrous Tumors of the Pleura of the Thorax: CT and FDG PET Characteristics in a Tertiary Referral Center. Medicine, 94(38), e1548. https://doi.org/10.1097/MD.0000000000001548
Ilgan, S., Dikmen, E., Cetinkanat, C. G., Dakak, M., & Güngör, A. (2014). Schwannomatozis of the Chest Wall: FDG PET Findings. Molecular imaging and radionuclide therapy, 23(2), 64–66. https://doi.org/10.4274/mirt.353
Chadaz, T., Hobbs, S. K., & Son, H. (2013). Chest wall sarcoma: 18F-FDG PET/CT in a patient with Li-Fraumeni syndrome. Clinical nuclear medicine, 38(10), 818–820. https://doi.org/10.1097/RLU.0b013e3182a20033
Carter, B. W., Benveniste, M. F., Betancourt, S. L., de Groot, P. M., Lichtenberger, J. P., 3rd, Amini, B., & Abbott, G. F. (2016). Imaging Evaluation of Malignant Chest Wall Neoplasms. Radiographics : a review
Molecular Oncologic Imaging 2023;3(3):01-07 7 publication of the Radiological Society of North America, Inc, 36(5), 1285–1306. https://doi.org/10.1148/rg.2016150208
Jiang, L., Gao, Y., Sheng, S., Xu, M., Lu, L., & Lu, H. (2011). A first described chest wall metastasis from colon cancer demonstrated with (18)F-FDG PET/CT. Hellenic journal of nuclear medicine, 14(3), 316–317.
David, E. A., & Marshall, M. B. (2011). Review of chest wall tumors: a diagnostic, therapeutic, and reconstructive challenge. Seminars in plastic surgery, 25(1), 16–24. https://doi.org/10.1055/s-0031-1275167
Mullan, C. P., Madan, R., Trotman-Dickenson, B., Qian, X., Jacobson, F. L., & Hunsaker, A. (2011). Radiology of chest wall masses. AJR. American journal of roentgenology, 197(3), W460–W470. https://doi.org/10.2214/AJR.10.7259
Bandi, V., Lunn, W., Ernst, A., Eberhardt, R., Hoffmann, H., & Herth, F. J. (2008). Ultrasound vs. CT in detecting chest wall invasion by tumor: a prospective study. Chest, 133(4), 881–886. https://doi.org/10.1378/chest.07-1656
Cohen, L. M., Schwartz, A. M., & Rockoff, S. D. (1986). Benign schwannomas: pathologic basis for CT inhomogeneities. AJR. American journal of roentgenology, 147(1), 141–143. https://doi.org/10.2214/ajr.147.1.141
O'Sullivan, P., O'Dwyer, H., Flint, J., Munk, P. L., & Muller, N. (2007). Soft tissue tumours and mass-like lesions of the chest wall: a pictorial review of CT and MR findings. The British journal of radiology, 80(955), 574–580. https://doi.org/10.1259/bjr/16591964
Cheng, G., Newberg, A. B., & Alavi, A. (2011). Metastatic melanoma causing complete atrioventricular block--the role of FDG PET/CT in diagnosis. Clinical imaging, 35(4), 312–314. https://doi.org/10.1016/j.clinimag.2010.08.008
Halac, M., Cnaral, F., Sait, S., Ylmaz, S., Kerim, S., Sergülen, D., & Uslu, I. (2008). FDG PET/CT findings in recurrent malignant schwannoma. Clinical nuclear medicine, 33(3), 172–174. https://doi.org/10.1097/RLU.0b013e318162d922
Wasyliw, C. W., & Caride, V. J. (2005). Incidental detection of bilateral elastofibroma dorsi with F-18 FDG PET/CT. Clinical nuclear medicine, 30(10), 700–701. https://doi.org/10.1097/01.rlu.0000178786.99368.1d
Okamoto, K., Tani, Y., Yamaguchi, T., Ogino, K., Tsuchioka, T., Nakajima, M., Yamaguchi, S., Sasaki, K., Kato, H., & Ohya, T. (2015). Asymptomatic Mesenchymal Hamartoma of the Chest Wall in Child With Fluorodeoxyglucose Uptake on PET/CT-Report of a Case. International surgery, 100(5), 915–919. https://doi.org/10.9738/INTSURG-D-14-00083.1
Yeom, Y. K., Kim, M. Y., Lee, H. J., & Kim, S. S. (2015). Solitary Fibrous Tumors of the Pleura of the Thorax: CT and FDG PET Characteristics in a Tertiary Referral Center. Medicine, 94(38), e1548. https://doi.org/10.1097/MD.0000000000001548
Koç, Z. P., Kara, P. Ö., Köksel, M. O., Sayar, H. (2023). Imaging Features of Chest Wall Mass in the Hybrid Imaging Modalities: SPECT/CT and PET/CT. Molecular Oncologic Imaging, 3(3), 1-7.
AMA
Koç ZP, Kara PÖ, Köksel MO, Sayar H. Imaging Features of Chest Wall Mass in the Hybrid Imaging Modalities: SPECT/CT and PET/CT. Molecular Oncologic Imaging. December 2023;3(3):1-7.
Chicago
Koç, Zehra Pınar, Pelin Özcan Kara, Mehmet Oğuz Köksel, and Hamide Sayar. “Imaging Features of Chest Wall Mass in the Hybrid Imaging Modalities: SPECT/CT and PET/CT”. Molecular Oncologic Imaging 3, no. 3 (December 2023): 1-7.
EndNote
Koç ZP, Kara PÖ, Köksel MO, Sayar H (December 1, 2023) Imaging Features of Chest Wall Mass in the Hybrid Imaging Modalities: SPECT/CT and PET/CT. Molecular Oncologic Imaging 3 3 1–7.
IEEE
Z. P. Koç, P. Ö. Kara, M. O. Köksel, and H. Sayar, “Imaging Features of Chest Wall Mass in the Hybrid Imaging Modalities: SPECT/CT and PET/CT”, Molecular Oncologic Imaging, vol. 3, no. 3, pp. 1–7, 2023.
ISNAD
Koç, Zehra Pınar et al. “Imaging Features of Chest Wall Mass in the Hybrid Imaging Modalities: SPECT/CT and PET/CT”. Molecular Oncologic Imaging 3/3 (December 2023), 1-7.
JAMA
Koç ZP, Kara PÖ, Köksel MO, Sayar H. Imaging Features of Chest Wall Mass in the Hybrid Imaging Modalities: SPECT/CT and PET/CT. Molecular Oncologic Imaging. 2023;3:1–7.
MLA
Koç, Zehra Pınar et al. “Imaging Features of Chest Wall Mass in the Hybrid Imaging Modalities: SPECT/CT and PET/CT”. Molecular Oncologic Imaging, vol. 3, no. 3, 2023, pp. 1-7.
Vancouver
Koç ZP, Kara PÖ, Köksel MO, Sayar H. Imaging Features of Chest Wall Mass in the Hybrid Imaging Modalities: SPECT/CT and PET/CT. Molecular Oncologic Imaging. 2023;3(3):1-7.