mmj Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi 2148-8118 2618-6020 Muğla Sıtkı Koçman Üniversitesi 10.47572/muskutd.1851024 Clinical Sciences (Other) Klinik Tıp Bilimleri (Diğer) Üçüncü Basamak Bir Sağlık Merkezinde Erken Gebelikte D Vitamini Eksikliği Prevalansı: Kesitsel Bir Çalışma Prevalence of Vitamin D Deficiency in Early Pregnancy: A Cross-Sectional Study at a Tertiary Care Center https://orcid.org/0000-0002-4083-7636 Kahyaoğlu Beyzanur UNIVERSITY OF HEALTH SCIENCES, İSTANBUL KARTAL DR. LÜTFİ KIRDAR HEALTH RESEARCH CENTER https://orcid.org/0000-0001-9877-1767 Temoçin Rezzan Berna UNIVERSITY OF HEALTH SCIENCES, İSTANBUL KARTAL DR. LÜTFİ KIRDAR HEALTH RESEARCH CENTER, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF OBSTETRICS AND GYNAECOLOGY https://orcid.org/0000-0001-6243-3993 Yılmaz Aylin UNIVERSITY OF HEALTH SCIENCES, İSTANBUL KARTAL DR. LÜTFİ KIRDAR HEALTH RESEARCH CENTER, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF OBSTETRICS AND GYNAECOLOGY https://orcid.org/0000-0001-7624-3656 Yıldız Pınar UNIVERSITY OF HEALTH SCIENCES, İSTANBUL ÜMRANİYE HEALTH RESEARCH CENTER, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF OBSTETRICS AND GYNAECOLOGY, PERINATOLOGY (MEDICINE) https://orcid.org/0000-0002-3965-543X Mat Emre UNIVERSITY OF HEALTH SCIENCES, İSTANBUL KARTAL DR. LÜTFİ KIRDAR HEALTH RESEARCH CENTER, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF OBSTETRICS AND GYNAECOLOGY https://orcid.org/0000-0002-3166-7129 Şanlıkan Fatih UNIVERSITY OF HEALTH SCIENCES, İSTANBUL KARTAL DR. LÜTFİ KIRDAR HEALTH RESEARCH CENTER, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF OBSTETRICS AND GYNAECOLOGY 04 29 2026 13 1 116 121 12 29 2025 04 06 2026 Copyright © 2014, Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi 2014 Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi

Vitamin D, kalsiyum metabolizması, immün düzenleme ve hücre büyümesinde önemli bir rol oynar. Erken gebelik dönemindeki vitamin D eksikliği, anne ve fetüs sağlığını olumsuz etkileyebilir. Bu çalışmanın amacı, İstanbul’da üçüncü basamak bir sağlık merkezine başvuran birinci trimester gebelerin vitamin D eksikliği prevalansını ve ilişkili faktörleri belirlemektir. Ocak 2020–Ocak 2024 tarihleri arasında antenatal kliniğe başvuran toplam 1105 gebe kadın retrospektif olarak analiz edildi. Vitamin D durumu yeterli, yetersiz ve eksik olarak sınıflandırıldı. Vitamin D eksikliği ayrıca hafif, orta ve ağır olarak kategorize edildi. Serum 25(OH)D düzeyleri yaş, mevsim ve aya göre değerlendirildi. Katılımcıların medyan yaşı 29 yıl (aralık 17–50) olup, medyan serum 25(OH)D düzeyi 11,1 ng/mL (ortalama ± SS: 13,7 ± 9,2) idi. Vitamin D eksikliği (

Vitamin D plays a crucial role in calcium metabolism, immune regulation, and cell growth. Deficiency during early pregnancy may adversely affect maternal and fetal health. The aim of this study was to determine the prevalence of vitamin D deficiency and related factors in pregnant women in their first trimester who attended a tertiary care center in Istanbul. A total of 1105 pregnant women who attended the antenatal clinic between January 2020 and January 2024 were retrospectively analyzed. Vitamin D status was classified as sufficient, insufficient, and deficient. Vitamin D deficiency was further categorized as mild, moderate and severe. Serum 25(OH)D levels were analyzed according to age, season, and month. The median age of participants was 29 years (range 17–50), and the median serum 25(OH)D level was 11.1 ng/mL (mean ± SD: 13.7 ± 9.2). Vitamin D deficiency (

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