mmj Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi 2148-8118 2618-6020 Muğla Sıtkı Koçman Üniversitesi ​Internal Diseases İç Hastalıkları Vücut Geliştiricide İntramuskuler Synthol Enjeksiyonuna Bağlı Lipoid Pnömoni Exogenous Lipoid Pneumonia Due To Intramuscular Injection of Synthol in a Bodybuilder https://orcid.org/0000-0002-3789-7769 Öcal Nesrin Health Sciences University, Gulhane Medical Faculty, Department of Chest Diseases, Ankara https://orcid.org/0000-0002-9923-926X Günal Armağan Health Sciences University, Gulhane Medical Faculty, Department of Medical Pathology, Ankara https://orcid.org/0000-0002-9079-1701 Arslan Yakup Health Sciences University, Gulhane Medical Faculty, Department of Chest Diseases, Ankara https://orcid.org/0000-0001-8104-6921 Kaçmaz Berat Health Sciences University, Gulhane Medical Faculty, Department of Chest Diseases, Ankara https://orcid.org/0000-0003-2286-0135 Coşkun Ali Health Sciences University, Gulhane Medical Faculty, Department of Medical Pathology, Ankara https://orcid.org/0000-0003-1559-6516 Karan Bahadır Can Health Sciences University, Gulhane Medical Faculty, Department of Chest Diseases, Ankara https://orcid.org/0000-0003-2596-3113 Doğan Deniz Health Sciences University, Gulhane Medical Faculty, Department of Chest Diseases, Ankara https://orcid.org/0000-0002-8789-7775 Taşçı Cantürk Health Sciences University, Gulhane Medical Faculty, Department of Chest Diseases, Ankara Uçar Ergün Health Sciences University, Gulhane Medical Faculty, Department of Chest Diseases, Ankara 03 20 2019 6 1 48 51 08 31 2018 09 28 2018 Copyright © 2014, Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi 2014 Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi

Bu makalede kas dolgusu amacıyla sentetik biryağ türevi olan “Synthol” un tekrarlayan intramuskuler kullanımı nedeniylegelişen kronik eksojen lipoid pnömoni olgusu sunulmuştur. Göğüs kaslarınıbüyütmek için Synthol kullanan 40 yaşında erkek hasta, bir yıl içinde ilerleyennefes darlığı ile birlikte polikliniğimize başvurdu. Toraks tomografisindeinterstisyel akciğer hastalığı ile uyumlu retikülasyonlar ve septalkalınlaşmalar izlenmekteydi. Hastaya bronkoskopi yapıldı. Bronkoalveolar lavaj vetransbronşiyal biyopsi (TBB) alındı. TBB'nin histopatolojik incelemesinde,intraalveoler ve interstisyel yağlı makrofajlar, yağ partikülleri etrafındakidev hücreler ve ekstraselüler yağ partikülleri gözlendi. Örnek “lipoid pnömoni”olarak raporlandı. Bizim bilgimize göre Synthol'un intramusküler kullanımınabağlı ekzojen lipoid pnömonisi şimdiye kadar bildirilmemiştir ve olgumuzliteratürdeki ilk olgudur.

We report a case of chronic exogenous lipoidpneumonia that developed due to recurrent intramuscular use of “Synthol”, asynthetic oil derivative, for muscle filling. 40-year-old man, who had usedSynthol to enlarge his pectoral muscles, was admitted to the chest diseasespolyclinic with shortness of breath progressing within a year. On computerizedtomography of thorax there were reticulations and septal thickenings consistentwith interstitial lung disease. The patient underwent bronchoscopy.Bronchoalveolar lavage and transbronchial biopsy (TBB) were performed. In thehistopathologic study of TBB, intraalveolar and interstitial fatty macrophages,giant cells around fat particles and extracellular fat particles were observedand the specimen was reported as "lipoid pneumonia". According to ourknowledge, exogenous lipoid pneumonia due to intramuscular use of Synthol hasnot been reported heretofore and this is the first case in the literature.

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