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Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi

2148-8118 2618-6020

Muğla Sıtkı Koçman Üniversitesi

Internal Diseases

İç Hastalıkları

Duration of Breastfeeding and Its Relationship with Autism Severity in Cases with Autism Spectrum Disorder

Otizm Spektrum Bozukluğu Olan Olgularda Anne Sütü Alım Süreleri ve Otizm Şiddetiyle İlişkisi

https://orcid.org/0000-0001-7120-1561

Şahin

Nilfer

Muğla Sıtkı Koçman Üniversitesi Tıp Fakültesi Çocuk ve Ergen Ruh Sağlığı ve Hastalıkları Anabilim Dalı, Muğla

https://orcid.org/0000-0002-1830-1720

Balkan

Damla

Muğla Sıtkı Koçman Üniversitesi Tıp Fakültesi Çocuk ve Ergen Ruh Sağlığı ve Hastalıkları Anabilim Dalı, Muğla

https://orcid.org/0000-0002-0490-925X

Kırlı

Ulviye

Muğla Sıtkı Koçman Üniversitesi Tıp Fakültesi Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Muğla

03 20 2019

6 1 5 9 12 14 2018 01 16 2019

2014

Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi

Autism Spectrum Disorder (ASD) is a group ofneurodevelopmental disorder characterized with social interaction,communication impairments and stereotypic behaviour. Although the aetiology ofautism has not yet been fully elucidated, several hypotheses have been proposedto explain the aetiology of autism. Conditions related to breastfeeding, suchas duration of breastfeeding, timing have been proposed as environmental riskfactors for autism. The aim of this study was to evaluate the relationshipbetween breastfeeding time and autism severity in children with ASD. The studyincluded 88 children with autism who were diagnosed according to DSM-5diagnostic criteria and 61 healthy age-matched children. Autism severity wasassessed by the Childhood Autism Rating Scale (CARS). Demographic data and CARSscores were obtained by scanning the file information. Mean breastfeeding timewas 12.97±8.13 months in the ASD group while breastfeeding time was 15.55±7.81months in the control group. The difference between the groups was notstatistically significant (p=0.055). There was a negative correlation betweenCARS scores and breast milk intake times in the ASD group (p<0.001, r:-0.435). In this study, breastfeeding times in children with ASD were similarto healthy controls. However, the severity of ASD was found to be increased asthe duration of breastfeeding decreased in children with ASD. Further studiesare needed to clarify the potential pathophysiological role of breastfeeding inthe aetiology of ASD and its relationship with disease severity.

Otizm Spektrum Bozukluğu (OSB), sosyal etkileşimve iletişimde bozulmalar ve stereotipik davranışlarla karakterize bir grup nörogelişimselbozukluktur. Otizm etyolojisi henüz tam olarak aydınlatılamamış olmaklabirlikte otizm etyolojisini açıklamak için birçok hipotez öne sürülmüştür. Annesütü alım süreleri, zamanlamaları gibi emzirme ile ilgili durumlar, otizm içinçevresel risk faktörleri olarak öne sürülmüştür. Bu çalışmada OSB’li çocuklardaanne sütü alım sürelerinin otizm şiddetiyle ilişkisinin değerlendirilmesiamaçlanmıştır. Çalışmaya DSM-5 tanı kriterlerine göre OSB tanısı almış 88 çocukve yaş ve cinsiyet olarak eşleştirilmiş 61 sağlıklı çocuğun verileri dahiledildi. Otizm şiddeti Çocukluk Otizm Dereceleme Ölçeği (ÇODÖ) iledeğerlendirildi. OSB grubunda ortalama anne sütü alma süresi 12.97±8.13 ay ikenkontrol grubunda bu süre 15.55±7.81 ay idi. Gruplar arasında ortaya çıkan bufark istatistiksel olarak anlamlı değildi (p=0.055). OSB grubunda ÇODÖpuanlarıyla anne sütü alım süreleri arasında negatif korelasyon saptandı(p<0.001, r:-0.435). Bu çalışmada OSB’li çocuklarda anne sütü alım sürelerisağlıklı kontrollere benzer bulundu. Bununla birlikte OSB’li çocuklarda annesütü alım süreleri kısaldıkça OSB şiddetinin arttığı bulundu. Anne sütünün OSBetiyolojisindeki potansiyel patofizyolojik rolünün ve hastalık şiddetiyleilişkisinin aydınlatılması için daha geniş çaplı çalışmalara ihtiyaç vardır.

Anne Sütü Otizm Otizm Şiddeti

Autism Autism Severity Breastfeeding

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