mmj Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi 2148-8118 2618-6020 Muğla Sıtkı Koçman Üniversitesi 10.47572/muskutd.617217 ​Internal Diseases İç Hastalıkları IntraUterineInsemination with Micro Fluid Sperm Sorting Chip Method: Case Report Mikro Akışkan Sperm Ayıklama Chip Yöntemi ile İntraUterinİnseminasyon: Olgu Sunumu https://orcid.org/0000-0003-2023-8246 Karagöz Can Nazlı muğla sıtkı koçman üniversitei tıp fakültesi kadın hastalıkları ve doğum AD https://orcid.org/0000-0002-6381-8059 Bozkurt Köseoğlu Sezen MUĞLA SITKI KOÇMAN ÜNİVERSİTESİ, TIP FAKÜLTESİ 08 31 2021 8 2 141 144 09 09 2019 01 08 2020 Copyright © 2014, Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi 2014 Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi

World Health Organization (WHO) infertility; a couple's unprotected sexual inter course for one year. 15% of couples of reproductive age have infertility. Nowadays, the first step assisted reproduction technique is intra uterine insemination (IUI). This method allows the sperm and egg to meet in a controlled manner and with this method, sperm washing process and the catheter allows the determination of sperm into the uterus. Sperm washing techniques are gradient, flotation and micro fluidic chip method. The main principle of sperm washing is to collect the best quality sperm in the fastest and most gentle way. The main purpose of this type of sperm selection, no DNA fragmentation, have a nucleus, motile, is to provide a morphologically normal sperm. In this case, we aimed to investigate the utility of micro fluidic chip technique in insemination process.

Dünya Sağlık Örgütü (WHO) infertiliteyi; bir çiftin bir yıl boyunca düzenli korunmasız cinsel ilişkiye girdiği halde gebe kalamama durumu olarak tanımlamaktadır. İnfertilite üreme çağındaki çiftlerin yaklaşık %15 inde gözlenmektedir. Günümüzde ilk basamak yardımla üreme tekniği intrauterininseminasyon (IUI) yöntemidir. Bu yöntem kontrollü olarak spontan ya da medikal ajanlarla gerekli olgunluğa getirilen kadın üreme hücresi ile uyumlu olarak erkek üreme hücresi olan ve gerekli yıkama işlemlerinden geçirilen spermin bir kateter yardımı ile kontrollü olarak buluşmasını amaçlamaktadır. Sperm yıkama teknikleri dansitegradiyent, yüzdürme ve son dönemde mikro akışkan chip yöntemidir. Sperm yıkamada ana prensip en iyi kalitedeki spermi en hızlı ve en nazik şekilde toplayabilmektir. Bu tür sperm seçiminin ana amacı, DNA fragmantasyonu olmayan çekirdeğe sahip, hareketli, morfolojik olarak normal bir sperm sağlamaktır. Biz bu olgu ile yeni bir teknik olan Mikro akışkan sperm ayıklama chip yönteminin intrauterininseminasyon işleminde kullanılabilirliğini incelemeyi amaçladık.

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