Erkek Hastada Cilt Metastazı ile Tespit Edilen Meme Karsinomu Olgu Sunumu

Yıl 2021, Cilt: 8 Sayı: 2, 148 - 151, 31.08.2021

Hülya Etem

https://doi.org/10.47572/muskutd.665034

Öz

Ciltte tümor metastazı; primeri bilinmeyen viseral bir malignitenin ya dadaha önce tespit edilip tedavi edilmiş bir malignitenin nüks bulgusu olarak görülebilir. Erkeklerde meme kanseri ve meme kanserinin cilt metastazı çok nadir görülmektedir. Erkekte meme kanseri tüm meme kanserlerinin %0.6'sını oluşturur. Erkek maligniteleri içerisinde %1'den daha az kısmını temsil eder. Erkeklerde meme kanserine sık rastlanılmadığı için kolayca atlanabilir ve çoğu zaman kesin tanı ve ayırıcı tanıda akla gelmez. Meme kanseri; meme cildinde oluşan, kronik cilt lezyonları ile karıştırılabilmektedir. Bu çalışmada sol omuz ve göğüs cildinde, lezyonları nedeniyle daha önceden farklı hekimlere başvurmuş erkek hastanın son başvurusunda cilt biyopsisi alınarak değerlendirildi. Karsinom metastazı olarak tanı verildi ve primer odağın meme olabileceği belirtildi. Olgunun ileri tetkik ve incelemesinde sol meme üst dış kadranda kitle ve boyun sol yarısı cildinde, bilateral aksillada, akciğerde metastazlar saptandı. Bu çalışma; erkek hastaların özellikle meme-gögüs cildindeki kronik lezyonlarında ''meme karsinomu'' olasılığının akılda tutulması gerektiğini vurgulamak ve erkek meme kanserlerini değerlendirmek için hazırlanmıştır.

Anahtar Kelimeler

Cilt Metastazı, Erkek Hasta, Meme Kanseri

Case Report of Breast Carcinoma Detected by Skin Metastasis in a Male Patient

Öz

Tumor metastasis in the skin can be seen either as a recurrence of a visceral malignancy of unknown primary origin or as a previously detected and treated malignancy. Breast cancer and Skin Metastasis of breast cancer is very rare among men. Male breast cancer accounts for 0.6% of all breast cancers and represents less than 1% of all male malignancies. Since breast cancer is not a common disease in men, its diagnosis can be easily missed, and most of the time it is not taken into consideration in the definitive and differential diagnosis. Breast cancer can be confused with non-healing chronic skin lesions on the breast skin. In this study, a male patient who had previously admitted to different physicians due to lesions on his left shoulder and chest skin was evaluated by taking a skin biopsy at his last admission. The diagnosis was metastatic carcinoma and it was reported that the primary focus might be the breast. Further tests and examination of the patient revealed a mass in the upper outer quadrant of the left breast and metastases in the left half of the neck, bilateral axillae, and lungs. The aim of this study was to emphasize the possibility of breast carcinoma in male patients, especially in chronic lesions of the breast-chest skin and to evaluate male breast cancers.

Anahtar Kelimeler

Skin Metastasis, Male Patient, Breast Cancer

Kaynakça

• 1. Romics L Jr, O’Brien ME, Relihan N, O’Connell F, Redmond HP. Intracystic papillary carcinoma in a male as a rare presentation of breast cancer: a case report and literature review. J Med Case Rep. 2009; 13: 13.
• 2. Harris JR, Morrow M, Norton L. Malignant tumors of the breast. In: DeVita VT, Hellman S, Rosenberg SA, Eds.: Cancer: Principles and Practice of Oncology. Philadelphia:LB Lippincott Company, 5 th Edition, 1998, pp 1557-616.
• 3. Alıcı S, Kösem M, Çalka Ö, Kotan Ç, Mercan R. Erkek meme karsinomu (Olgu Sunumu). Türkderm. 2003; 37(2): 17-119.
• 4. Tatar D, Böncü M,Yıldırım Y, Halilçolar H, Yener AG. Erkekte İleri Evre Meme Kanseri (Olgu Sunumu). Akciğer Arşivi. 2002; 1: 37-40.
• 5. Auerschmitz GJ, Karan D, Zwiefel K, Bender HG, Mohrmann S. An Unusual Case of Advanced Bilateral Male Breast Cancer. Onkol. 2008; 31(10): 542-4.
• 6. Rudlowski C. Male breast cancer. Breast Care 2008; 3:183–9.
• 7. Krause W. Male breast cancer-an andrological disease: Risk factors and diagnosis. Andrologia. 2004; 36: 346-54.
• 8. Handerson IC, Harris JR, Kinne DW et all. Cancer of the breast. In De Vita VT, Helman JrS, Rosenberg SA (eds). Cancer, principal and practice of oncology. Philadelphia; The Murray Printing Company. 1989; 1197- 268.
• 9. Sevinç Aİ, Canda AE, Atilla K. Erkeklerde meme kanseri; 22 olgu. Meme Sağlığı Derg. 2007; 3: 14-8.
• 10. Heller KS, Rosen PP, Schottenfeld D et al. Male breast cancer: a clinicopathologic study of 97 cases. Ann Surg. 1978; 188:60-5.
• 11. Rollins-Raval M, Chivukula M, Tseng GC, Jukic D, Dabbs DJ. An immunohistochemical panel to differentiate metastatic breast carcinoma to skin from primary sweat gland carcinomas with a review of the literature Arch Pathol Lab Med. 2011; 135(8):975-83.
• 12. Molina Garrido MJ, Guillén Ponce C, Soto Martínez JL, Martínez Y Sevila C, Carrato Mena A. Cutaneous metastases of lung cancer. Clin Transl Oncol. 2006;8:330–3.
• 13. Nashan D, Müller ML, Braun-Falco M, Reichenberger S, Szeimies RM, Bruckner-Tuderman L. Cutaneous metastases of visceral tumours: A review. J Cancer Res Clin Oncol. 2009;135:1–14.
• 14. Schwartz RA: Cutaneous metastatic disease. J Am Acad Dermatol. 1995;33:161-82.
• 15. Karakuzu A, Koc M, Ozdemir S. Multiple cutaneous metastases from male breast carcinoma. J Am Acad Dermatol. 2006; 55: 1101-2.
• 16. Hogg RP, Ayshford C, Watkinson JC. Parotid duct carcinoma arising in bilateral chronic sialadenitis. J Laryngol Otol. 1999; 113: 686-8.
• 17. Kleinsasser O, Klein HJ, Hübner G. Salivary duct carcinoma:a group of salivary gland tumors analogue to mammary duct carsinoma. Arch Klin Exp Ohren Nasen Kehlkopfheilkd. 1968; 192: 100-15.
• 18. Swanson PE, Pettinato G, Lillemoe TJ, et al. Gross cystic disease fluid protein-15 in salivary gland tumors. Arch Pathol Lab Med. 1991;115(2):158–63.
• 19. Schwartz LE, Begum S, Westra WH, Bishop JA. GATA3 immunohistochemical expression in salivary gland neoplasms. Head Neck Pathol. 2013;7(4):311–5.