The Evaluation of Basal Ganglia in Pediatric Patients with Cerebral Palsy Using Magnetic Resonance Histogram Analysis

Yıl 2024, Cilt: 11 Sayı: 2, 97 - 101, 31.08.2024

Ferit Doğan , Mehmet Demir , Hüseyin Gümüş , Celil Yılmaz

https://doi.org/10.47572/muskutd.1440247

Öz

The aim of this study is to detect changes in the basal ganglia using magnetic resonance imaging (MRI) histogram in patients with cerebral palsy (CP) who do not have pathological signal changes in the basal ganglia on conventional MRI images. A retrospective evaluation was made of the images of 40 children with CP and 60 children with no significant intracranial findings on brain MRI examination. The histogram parameters of mean, variance, skewness, kurtosis, 1st percentile (P), 10th P, 50th P, 90th P and 99th P were calculated for each patient and control group on the areas identified in the head of the thalamus, lentiform nucleus and nucleus caudatus and these were evaluated separately for each case. A significant difference was found between the groups in terms of the mean, kurtosis and 50th P values of histogram parameters obtained from the thalamus (p=0.001, p=0.002, p=0.025, respectively). A significant difference was found between the mean, skewness, kurtosis and 1st P values of histogram parameters obtained from the lentiform nuclei (p=0.021, p=0.005, p=0.015, p=0.035, respectively). A significant difference was found between the mean, kurtosis, 90th P and 99th P values of the histogram parameters obtained from the head section of the nucleus caudatus (p=0.002, p=0.03, p=0.004, p=0.042, respectively). Texture analysis can produce objective features that may indicate differences in the basal ganglia and thalamus in patients with CP. Texture analysis can identify changes in the basal ganglia in patients with CP who do not have pathological signal changes on conventional MRI images.

Anahtar Kelimeler

Basal ganglia, Texture analysis, Cerebral palsy, Thalamus

Serebral Palsili Pediatrik Hastalarda Bazal Ganglionların Manyetik Rezonans Histogram Analizi Kullanılarak Değerlendirilmesi

Öz

Konvansiyonel manyetik rezonans görüntüleme (MRG) görüntülerinde bazal ganglionlarda patolojik sinyal değişiklikleri olmayan serebral palsili (SP) hastalarda MRG histogramını kullanarak bazal ganglionlardaki değişiklikleri tespit etmeyi amaçladık. Serebral palsili 40 çocuk ve beyin MRG incelemesinde anlamlı intrakraniyal bulgusu olmayan 60 çocuğun görüntüleri retrospektif olarak değerlendirildi. Ortalama, varyans, çarpıklık, basıklık, 1. yüzdelik (P), 10. P, 50. P, 90. P ve 99. P histogram parametreleri her hasta ve kontrol grubu için talamus, lentiform ve kaudat nukleuslardan tanımlanan alanlarda hesaplandı ve her vaka için ayrı ayrı değerlendirildi. Talamustan elde edilen histogram parametrelerinin ortalama, basıklık ve 50. P değerleri açısından gruplar arasında anlamlı fark bulundu (sırasıyla p=0.001, p=0.002, p=0.025). Lentiform çekirdeklerden elde edilen histogram parametrelerinin ortalama, çarpıklık, basıklık ve 1. P değerleri arasında anlamlı bir fark bulunmuştur (sırasıyla p=0.021, p=0.005, p=0.015, p=0.035). Nukleus kaudatustan elde edilen histogram parametrelerinin ortalama, basıklık, 90. P ve 99. P değerleri arasında anlamlı farklılık tespit edildi (sırasıyla p=0.002, p=0.03, p=0.004, p=0.042). Doku analizi, serebral palsili hastalarda bazal ganglionlar ve talamustaki farklılıkları gösterebilecek objektif özellikler üretebilir. Doku analizi, konvansiyonel MRG görüntülerinde patolojik sinyal değişikliği olmayan SP'li hastalarda bazal ganglionlardaki değişiklikleri tanımlayabilir.

Anahtar Kelimeler

Bazal Ganglionlar, Doku Analizi, Serebral Palsi, Talamus

Etik Beyan

Çalışma için etik kurul onamı alınmıştır

Destekleyen Kurum

yok

Kaynakça

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