In this study, construction of amperometric glucose biosensor was carried out by immobilizing of glucose oxidase (GOD) on carbon paste electrode (CPE) which was coated with polyaniline (PANI) by cyclic voltammetry technique. Since the current values to be measured depending on the glucose concentration will be affected by the graphite:mineral oil composition of the electrode, this parametres were optimized by response surface methodology (RSM). For this, State Ease Design Expert 188.8.131.52. (Serial Number: 0021-6578) software software was used applying Optimal Design. By using data obtained, Design Expert software suggested quadratic model to predict current values in terms of working parameters. In study, experimentally measured current values and predicted values by model were considerably found compatable and suitability of model was supported by ANOVA test.
|Yayımlanma Tarihi||4 Nisan 2022|
|Gönderilme Tarihi||2 Temmuz 2021|
|Kabul Tarihi||15 Aralık 2021|
|Yayınlandığı Sayı||Yıl 2022 Cilt: 7 Sayı: 1|
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