A Nano-zinc Oxide-based Drug Delivery System and its Biomedical Applications

Year 2024, Volume: 9 Issue: 3, 193 - 203, 31.12.2024

Tripti Dewangan , Chiranjeev Singh

https://doi.org/10.28978/nesciences.1606636

Abstract

Zinc Oxide Nanomaterials (ZnO-NMs) are significant nanomaterials utilized in biological applications. Biopolymers have been widely employed in biomedicine due to their various benefits. ZnO nanoparticles coated with biopolymers have exhibited considerable promise in the medical domain. Over the last two decades, ZnO-NM has demonstrated remarkable luminous capabilities, and their affordability, minimal toxicity, and biological compatibility have positioned these nanomaterials as prime prospects for bioimaging applications. Identifying other advantageous characteristics, including the capacity to generate harmful Reactive Oxygen Species, elevated catalytic effectiveness, robust adsorption capacity, and an elevated isoelectric point, further establishes them as attractive nanomaterials for medicinal and diagnostic purposes. This document reviews current advancements in applying ZnO-NM for drug delivery and theranostics in various illnesses, including bacterial infections and cancer. The adaptation enhances the suitability of ZnO-NM by utilizing a biopolymer as a sealing driver, possibly augmenting efficacy in Drug Delivery (DD) and biomedical purposes. ZnO-NM, covered with biopolymers, has extensive applications in biomedicine, including drug delivery, biological imaging, and therapeutic interventions for cancer, microbiological diseases, and diabetes. Moreover, enhancements to ZnO-NM for pharmaceutical delivery frequently involve initiatives to augment biocompatibility, facilitate focused DD, and enhance uptake while mitigating side effects. The alterations improve the stabilization of nanomaterials and facilitate the connection of specific protein molecules for focused delivery and efficacy against diabetics and microbe illnesses.

Keywords

Zinc Oxide, Drug Delivery System, Biomedical Applications, Nanotechnology

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