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<article  article-type="case-report"        dtd-version="1.4">
            <front>

                <journal-meta>
                                    <journal-id></journal-id>
            <journal-title-group>
                                                                                    <journal-title>Niğde Tıp Dergisi</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">3023-7149</issn>
                                                                                            <publisher>
                    <publisher-name>Niğde Ömer Halisdemir Üniversitesi</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id pub-id-type="doi">10.70846/nigdetip.1813909</article-id>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Psychiatry</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Psikiyatri</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <article-title>SEİZURE TRİGGERED BY SUDDEN DİSCONTİNUATİON OF PREGABALİN: A CASE REPORT</article-title>
                                                                                                                                                                                                <trans-title-group xml:lang="tr">
                                    <trans-title>PREGABALİNİN ANİDEN KESİLMESİNİN TETİKLEDİĞİ NÖBET: BİR VAKA RAPORU</trans-title>
                                </trans-title-group>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0003-0401-8622</contrib-id>
                                                                <name>
                                    <surname>Gündoğdu</surname>
                                    <given-names>İlknur</given-names>
                                </name>
                                                                    <aff>Samsun Ruh ve Sinir Hastalıkları Hastanesi</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20260326">
                    <day>03</day>
                    <month>26</month>
                    <year>2026</year>
                </pub-date>
                                                    <issue>5</issue>
                                        <fpage>254</fpage>
                                        <lpage>259</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20251030">
                        <day>10</day>
                        <month>30</month>
                        <year>2025</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20251209">
                        <day>12</day>
                        <month>09</month>
                        <year>2025</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 2024, Niğde Tıp Dergisi</copyright-statement>
                    <copyright-year>2024</copyright-year>
                    <copyright-holder>Niğde Tıp Dergisi</copyright-holder>
                </permissions>
            
                                                                                                <abstract><p>Pregabalin is currently used in the treatment of pain, anxiety disorders and partial seizures. Pregabalin also has a relaxing and euphoric effect. For this reason, it is frequently abused. There is no definitive guideline for the treatment of pregabalin addiction. This case describes the emergence of an epileptic seizure in a healthy adult with the sudden discontinuation of high-dose pregabalin in the treatment of pregabalin addiction. In the literature, no similar case has been reported.</p></abstract>
                                                                                                                                    <trans-abstract xml:lang="tr">
                            <p>Pregabalin günümüzde ağrı, anksiyete bozuklukları ve parsiyel nöbetlerin tedavisinde kullanılmaktadır. Ayrıca pregabalinin rahatlatıcı ve öforik bir etkisi vardır. Bu nedenle sıklıkla kötüye kullanılır. Pregabalin bağımlılığının tedavisi için kesin bir kılavuz yoktur. Bu olgu sunumunda, pregabalin bağımlılığı tedavisinde hastanın kullandığı yüksek doz pregabalinin ani kesilmesi sonucu sağlıklı bir yetişkinde epileptik nöbet ortaya çıkması anlatılmaktadır. Literatürde benzer bir olguya rastlanılmamıştır.</p></trans-abstract>
                                                            
            
                                                            <kwd-group>
                                                    <kwd>High dose pregabalin</kwd>
                                                    <kwd>  pregabalin discontinuation</kwd>
                                                    <kwd>  discontinuation seizures</kwd>
                                            </kwd-group>
                                                        
                                                                            <kwd-group xml:lang="tr">
                                                    <kwd>Yüksek doz pregabalin</kwd>
                                                    <kwd>  pregabalin kesilmesi</kwd>
                                                    <kwd>  kesilme nöbeti</kwd>
                                            </kwd-group>
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                                                    <funding-source>
                                <named-content content-type="funder_name">yok</named-content>
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    </front>
    <back>
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