Evaluation of Main Inflammatory Markers on Peripheral Vertigo Attack

Yıl 2021, Cilt: 2 Sayı: 1, 45 - 49, 25.01.2021

Alper Dilci Raşit Cevizci

Öz

Objective: The aim of this study is to evaluate the main inflammatory markers; neutrophile lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), mean platelet volume (MPV), c reactive protein (CRP), lactate dehydrogenase (LDH) and creatine kinase (CK) in patients with acute peripheral vertigo attack.
Methods: The records of patients files and laboratory results were analyzed retrospectively. The measures of complete blood count and basic biochemical test were compared in acute peripheral vertigo attack between patient and control group.
Results: The sample consists of 119 patients and 98 healthy controls are included in the control group. There is not any statistically significant change of main inflammatory measures between two groups.
Conclusion: Peripheral vertigo can be caused by many diseases with various pathologies. There may be various mechanisms besides inflammation and atherosclerosis of microvascular structures. The results of this study states that etiology of peripheral vertigo attack may not be related with ischemia and inflammation; it may be related with viral etiology.

Anahtar Kelimeler

vertigo, inflammation, markers, neutrophile lymphocyte ratio, platelet lymphocyte ratio

Kaynakça

• 1. Temirbekov D, Sakalli E. Effects of peripheral vertigo on inflammatory and immunologic laboratory markers. Ear Nose Throat J. 2020;99(7):470-474.
• 2. Goddard JC, Fayad JN. Vestibular neuritis. Otolaryngol Clin North Am 2011;44(2):361-365.
• 3. M von Brevern M, Radtke A, Lezius F, et al. Epidemiology of benign parosymal positional vertigo: a population based study. J Neurol Neurosurg Psychiatry 2007;78(7):710-715.
• 4. Chung JH, Lim J, Jeong JH, et al. The significance of neutrophile to lymphocyte ratio and platelet to lymphocyte ratio in vestibular neuritis. Laryngoscope 2015;125(7):257-261.
• 5. Sahin MI, Kokoglu K, Gulmez E. Mean platelet volume, neutrophile- and platelet to lymphocyte ratios are elevated in vestibular neuritis. J Clin Neurosci 2019;67-134-138.
• 6. Seo YJ, Jeong JH, Choi JY, et al. Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio: novel markers for diagnosis and prognosis in patients with idiopathic sudden sensorineural hearing loss. Dis Markers 2014;2014:702-807.
• 7. Akil E, Bulut A, Kaplan I, et al. The increase of carcinoembryonic antigen (CEA), high-sensitivity C-reactive protein, and neutrophile/lymphocyte ratio in Parkinson’s disease. Neurol Sci 2015;36(3):423-428.
• 8. Turkmen K, Guney I, Yerlikaya FH, et al. The relationship between neutrophile-to-lymphocyte ratio and inflammation in end-stage renal disease patients. Ren Fail 2012;34:155-159.
• 9. Ferroni P, Riondino S, Formica V, et al. Venous thromboembolism risk prediction in ambulatory cancer patients: clinical significance of neutrophile/lymphocyte raio and platelet/lymphocyte ratio. Int J Cancer 2015;136:1234-1240.
• 10. Kassner SS, Schöttler S, Bonaterra GA, et al. Proinflammatory activation of peripheral blood mononuclear cells in patients with vestibular neuritis. Audiol Neurotol 2011;16(4):242-247.
• 11. Ozler GS, Gunak G. Neutrophile-lymphocyte ratio: a new predictive and prognostic factor in patients with Bell palsy. J Craniofac Surg 2014;25(3):944-945.
• 12. Gary T, Pichler M, Belaj K, et al. Platelet-to-lymphocyte ratio:a novelmarker for critical limb ischemia in peripheral arterail occlusive disease patients. PloS One 2013;8:e67688.
• 13. Sagit M, Kavugudurmaz M, Guler S, et al. Impact of mean platelet volume on the occurence and severity of sudden sensorineural hearing loss. J Laryngol Otol 2013;127(10):972-976.
• 14. Ulu S, Ulu MS, Ahsen A, et al. Increased levels of mean platelet volume: a possible relationship with idopathic sudden hearing loss. Eur Arch Otorhinolaryngol 2013;270(11):2875-2878.
• 15. Ozbay I, Kahraman C, Balikci HH, et al. Neutrophile-to-lymphocyte ratio in patients with peripheral vertigo: a prospective controlled clinical study. Am J Otolaryngol 2014;35(6):699-702.