First Case of Cutaneous Leishmaniasis in Karaman Region

Abstract

Leishmaniasis is an infectious disease caused by intracellular parasitic protozoan species. Leishmaniasis can be classified as old world and new world. The clinical form seen in Central and South America is called New World Cutaneous Leishmaniasis (CL). The clinical form, most commonly seen in the Middle East, Southern Europe, Southwest Asia and Africa is called Old World CL. A 34-year-old male patient applied to the dermatology clinic due to crusty wounds located on his right leg and right hand. Dermatological examination revealed several erythematous plaques with hemorrhagic crusts, 2x3 cm in size, raised from the skin in the right tibial region, and a purplish erythematous plaque with a sharply circumscribed skin crusted in the dorsolateral of the right hand. Amastigote forms of leishmania were detected by Giemsa staining. The patient, was planned to be injected with 2 ml meglumine antimoniate twice a week for four weeks.

Keywords

• Leishmaniasis
• Cutaneous Leishmaniasis
• Meglumine Antimoniate

Project Number

yok

References

1. 1. Uzun S. Leishmaniasis. Dermatoloji’de. İçinde: Tüzün Y, Gürer MA, Serdaroğlu S, Oğuz O, Aksungur VL, editörler. İstanbul, Nobel Kitabevi; 2008; 659-77.
2. 2. Kevric I, Cappel MA and Keeling JH. New world and old world leishmania infections: a practical review. Dermatol Clin. 2015; 33(3): 579–93.
3. 3. McIlwee BE, Weis SE and Hosler GA. Incidence of endemic human cutaneous leishmaniasis in the United States. JAMA Dermatol. 2018;154:1032–39.
4. 4. Tsai PH, Chen YT, Liau JY, Huang MH, Hsu HM, Yeong EK, Hung CC. Molecular diagnosis and therapy for cutaneous leishmaniasis of a returned traveler from Mexico. J Microbiol Immunol Infect. 2021;54(6):1154-58.
5. 5. El Hajj L, Thellier M, Carrière J, Bricaire F, Danis M, Caumes E. Localized cutaneous leishmaniasis imported into Paris: a review of 39 cases. Int J Dermatol. 2004;43(2):120-5.
6. 6. Gurel MS, Ulukanligil M, Ozbilge H. Cutaneous leishmaniasis in Sanliurfa: epidemiologic and clinical features of the last four years (1997-2000). Int J Dermatol. 2002 41(1):32-7.
7. 7. Uzun S, Durdu M, Memisoglu HR. Türkiye’de kutanöz leishmaniasisin dünü, bugünü. Turkiye Parazitol Derg. 2012; 10: 133-8.
8. 8. WHO. Urbanization: an increasing risk factor for leishmaniasis. Wkly Epidemiol Rec. 2002; 77: 365-70.

9. 9. Ertabaklar H, Çalışkan SÖ, Boduç E, Ertuğ S. Kutanöz leishmaniasis tanısında direkt mikroskopi, kültür ve polimeraz zincir reaksiyonu yöntemlerinin karşılaştırılması. Mikrobiyol Bul. 2015; 49:77-84.
10. 10. Gürel MS, Yeşilova Y, Ölgen MK, Özbel Y. Türkiye’de kutanöz leishmaniasisin durumu. Turkiye Parazitoloji Derg. 2012;36:121-9.
11. 11. Dilek N, Dilek AR, Yuksel D, Saral Y, Metin A. Endemik bölge dışında kutanöz leishmaniasis. Dermatoz. 2015; 6:1-4.
12. 12. Bayazıt Y, Özcebe H. Şanlıurfa ili kent merkezinde kutanöz leishmaniasis insidans ve prevalansı. Türk Hij Den Biyol Derg. 2004; 61:9-14.
13. 13. Yanik M, Gurel MS, Simsek Z, Kati M. The psychological impact of cutaneous leishmaniasis. Clin Exp Dermatol. 2004; 29: 464-7.