Investigation of the relationship between comprehensive echocardiograhic findings and CRP/prealbumin ratio in patients with metabolic syndrome

Abstract

The predictive value of the C-reactive protein / Prealbumin (CRP/PAB) ratio for the assessment of left atrial (LA) functions in metabolic syndrome (Met-S) remains unclear. We enrolled 100 patients with newly diagnosed Met-S and 53 individuals as a control group. Detailed conventional and tissue Doppler echocardiographic examinations were performed, including measurements of volumes and functional indexes of LA. Mean CRP/PAB ratio values were not found to be different between groups (p=0,107). Mean mitral-A, tricuspid-A, and mitral-a’ velocities were found to be significantly different between groups (p-value for all<0,05). None of the volumetric and functional indexes of LA were found to be different between groups (p-value for all >0,05). After dividing the patients into groups as presenting wleft-right/left ventricular diastolic dysfunction (RVDD- LVDD) or not, again, none of the volumetric and functional indexes of LA were found to be different between groups (p-value for all >0,05). Finally, the CRP/PAB ratio was not found to be correlated with any of the indices of LA in patients with Met-S, while only active emptying volüme of LA was found to be correlated with the CRP/PAB ratio in the control group. We did not find any association between the CRP/PAB ratio and LA functions. To evaluate the predictive value of the CRP/PAB ratio for the assessment of LA functions in Met-S needs further studies with a large cohort population.

Keywords

• C-reactive protein-to-prealbumin ratio; metabolic syndrome
• left atrium function
• left atrium volume.

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