Research Article

Investigation of food preference in Alzheimer patients; Assessment of glycemic index and glycemic load of their diet

Volume: 41 Number: 1 March 29, 2024
EN

Investigation of food preference in Alzheimer patients; Assessment of glycemic index and glycemic load of their diet

Abstract

In this study, our objective was to investigate the food preferences of patients with Alzheimer’s-type dementia and healthy individuals of the same age and to compare the glycemic index and glycemic load of the preferred foods. This study was conducted with 55 patients, who were diagnosed with Alzheimer’s-type dementia by a neurologist, and 57 healthy individuals at the same age interval as the control group. The cognitive functions of the participants were assessed with the Standardized Mini-Mental State Exam (SMMSE). The food consumption preferences were determined following the obtainment of the three-day food consumption records and then the glycemic index and glycemic load of the diets was calculated. The carbohydrate amount consumed by Alzheimer's patients, the energy content of the diet, and the glycemic load were significantly higher (p<0.05) compared to the control group. The comparison of Alzheimer's patients, who were divided into two groups, mild dementia (SMMSE=18-23) and severe dementia (SMMSE≤17) according to the SMMSE scores, showed that patients with severe dementia consumed significantly more carbohydrates and the energy content of their diet was higher (p<0.05). We determined that Alzheimer's patients consumed more carbohydrates and sugar compared to the control group. The daily carbohydrate intake increased as the severity of the disease increased, however, the quality of the consumed carbohydrate remained the same.

Keywords

Supporting Institution

There are no supporting institutions

Project Number

There is not

Thanks

There is not

References

  1. Mergenthaler P, Lindauer U, Dienel GA, Meisel A. Sugar for the brain: the role of glucose in physiological and pathological brain function. Trends Neurosci. 2013;36(10):587-597.
  2. Harris JJ, Jolivet R, Attwell D. Synaptic energy use and supply. Neuron. 2012; 75(5):762-777.
  3. Hoyer S. The young-adult and normally aged brain. Its blood flow and oxidative metabolism. A review--part I. Arch Gerontol Geriatr. 1982;1(2):101-116.
  4. Resnick SM, Pham DL, Kraut MA, Zonderman AB, Davatzikos C. Longitudinal magnetic resonance imaging studies of older adults: a shrinking brain. J Neurosci. 2003;23(8):3295-3301.
  5. Hoyer S. The abnormally aged brain. Its blood flow and oxidative metabolism. A review - part II. Arch Gerontol Geriatr. 1982;1(3):195-207
  6. Keene JM, Hope T. Hyperphagia in dementia: 2. Food choices and their macronutrient contents in hyperphagia, dementia and ageing. Appetite. 1997;28(2):167-175.
  7. Heneka MT, Carson MJ, El Khoury J, Landreth GE, Brosseron F, Feinstein DL, et al Neuroinflammation in Alzheimer's Disease. Lancet Neurol. 2015; 14(4): 388–405.
  8. Heneka MT, O'Banion MK. Inflammatory processes in Alzheimer's disease. J Neuroimmunol. 2007;184(1-2):69-91. Kandimalla R, Thirumala V, Reddy PH. Is Alzheimer’s disease a Type 3 Diabetes? A critical appraisal. Biochim Biophys Acta. 2017;1863(5):1078–1089.

Details

Primary Language

English

Subjects

Central Nervous System

Journal Section

Research Article

Publication Date

March 29, 2024

Submission Date

July 19, 2023

Acceptance Date

December 20, 2023

Published in Issue

Year 2024 Volume: 41 Number: 1

APA
Yılmaz Can, F., Ergün, U., İnan, L., Gök, G., & Devrim Lanpir, A. (2024). Investigation of food preference in Alzheimer patients; Assessment of glycemic index and glycemic load of their diet. Deneysel Ve Klinik Tıp Dergisi, 41(1), 28-33. https://izlik.org/JA37CE69ZG
AMA
1.Yılmaz Can F, Ergün U, İnan L, Gök G, Devrim Lanpir A. Investigation of food preference in Alzheimer patients; Assessment of glycemic index and glycemic load of their diet. J. Exp. Clin. Med. 2024;41(1):28-33. https://izlik.org/JA37CE69ZG
Chicago
Yılmaz Can, Fatma, Ufuk Ergün, Levent İnan, Gökmen Gök, and Asli Devrim Lanpir. 2024. “Investigation of Food Preference in Alzheimer Patients; Assessment of Glycemic Index and Glycemic Load of Their Diet”. Deneysel Ve Klinik Tıp Dergisi 41 (1): 28-33. https://izlik.org/JA37CE69ZG.
EndNote
Yılmaz Can F, Ergün U, İnan L, Gök G, Devrim Lanpir A (March 1, 2024) Investigation of food preference in Alzheimer patients; Assessment of glycemic index and glycemic load of their diet. Deneysel ve Klinik Tıp Dergisi 41 1 28–33.
IEEE
[1]F. Yılmaz Can, U. Ergün, L. İnan, G. Gök, and A. Devrim Lanpir, “Investigation of food preference in Alzheimer patients; Assessment of glycemic index and glycemic load of their diet”, J. Exp. Clin. Med., vol. 41, no. 1, pp. 28–33, Mar. 2024, [Online]. Available: https://izlik.org/JA37CE69ZG
ISNAD
Yılmaz Can, Fatma - Ergün, Ufuk - İnan, Levent - Gök, Gökmen - Devrim Lanpir, Asli. “Investigation of Food Preference in Alzheimer Patients; Assessment of Glycemic Index and Glycemic Load of Their Diet”. Deneysel ve Klinik Tıp Dergisi 41/1 (March 1, 2024): 28-33. https://izlik.org/JA37CE69ZG.
JAMA
1.Yılmaz Can F, Ergün U, İnan L, Gök G, Devrim Lanpir A. Investigation of food preference in Alzheimer patients; Assessment of glycemic index and glycemic load of their diet. J. Exp. Clin. Med. 2024;41:28–33.
MLA
Yılmaz Can, Fatma, et al. “Investigation of Food Preference in Alzheimer Patients; Assessment of Glycemic Index and Glycemic Load of Their Diet”. Deneysel Ve Klinik Tıp Dergisi, vol. 41, no. 1, Mar. 2024, pp. 28-33, https://izlik.org/JA37CE69ZG.
Vancouver
1.Fatma Yılmaz Can, Ufuk Ergün, Levent İnan, Gökmen Gök, Asli Devrim Lanpir. Investigation of food preference in Alzheimer patients; Assessment of glycemic index and glycemic load of their diet. J. Exp. Clin. Med. [Internet]. 2024 Mar. 1;41(1):28-33. Available from: https://izlik.org/JA37CE69ZG