Ways of microbial escape from the immune system: A brief overview

Abstract

Viruses, bacteria and other microbes always try to disable our body system. Our immune system has a complex structure that continuously tries to defend our body against "foreign enemies". Microbes that infect other organisms encounter host immune responses and must overcome or evade innate and adaptive immune responses to successfully establish infection, providing fascinating insights into attack and escape. Many pathogens appear to have developed parallel pathways for escape, and several principles of escape are shared not only among members of the same genus but even among different organisms such as bacteria, viruses, fungi, and parasites. In this article, according to the recent findings, the unique escape strategies of microorganisms will be analyzed in more detail. Part of our immune system is responsible for clearing pathogens, either killing the pathogen directly or marking it for destruction by other immune cells. Therefore, it is possible to develop a new targeted therapy when the mechanism of microorganisms is fully understood. This review describes the mechanisms of interaction between the pathogen and its host in the context of infection.

Keywords

• Safety system
• Safety response
• Microorganism
• Infection
• Innate immune;
• Adaptive immunity
• Phagocytosis

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