Evaluation of the neuropathic component of pain in patients with fibromyalgia with painDETECT and DN4

Abstract

Fibromyalgia (FMS) is generally associated with neuropathic pain (NP) because of the neuropathic symptoms frequently observed in patients with FMS. The aim of the study is to evaluate the neuropathic component of FMS with the painDETECT (PD-Q) and Douler Neuropathic 4 (DN4) scales. Female patients diagnosed as FMS according to the American College of Rheumatology’s 2010 FMS criteria and female healthy volunteers are included in the study. After demographic evaluation, the patients and volunteers were asked to fill out Visual Analog Score (VAS), PD-Q, and DN4 scale forms. The Fibromyalgia Impairment Questionnaire (FIQ) evaluated life quality and function. There were 66 patients in the FMS group with a mean age of 46.16± 10.66 and 61 patients in the control group with a mean age of 44.93± 12.72. It was determined that there was a significant difference between the VAS, PD-Q, and DN4 values of FMS and control groups (tVAS = 5,025 p < 0.05, t PD-Q = 5,025 p < 0.05, tDN4 = 7,885 p < 0.05). The mean pain score (VAS) and NP level (DN4 and PD-Q) of FMS patients were significantly higher than healthy individuals. In addition, it was determined that VAS (p = 0.001) and PD-Q (p = 0.046) values were found to be significant predictors of the FIQ values. FMS patients may have pain with a neuropathic component, and it seems useful to evaluate neuropathic characteristics with PD-Q and DN4. If the components of pain are researched carefully, more improvement may be achieved in pain and functional capacity.

Keywords

• Chronic fatigue
• fibromyalgia
• fibromyalgia syndrome
• neuropathic pain

Supporting Institution

We did not have any support or funding during the study.

Project Number

0626

Ethical Statement

We declare that we have no ethical problem, conflict of interest or financial interest in the current study. We declare that the article has not been previously published, all authors contribute the data in article and the data is totally original.

Thanks

Thank you for your time for evaluating this study. Acknowledgement: None

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