Investigation of subtypes of hypertension and related factors in obese individuals

Abstract

Both systolic and diastolic hypertension (HT) have been associated with insulin resistance. There are also studies showing a relationship between insulin resistance and systolic hypertension, but not with diastolic hypertension. This issue is controversial. In this study, we examined the relationship between hypertension subgroups and obesity and insulin resistance. Our study is retrospective and 391obese individuals were divided into 2 groups: normotension group and newly diagnosed hypertension group. The risk of HT in men was found to be 2.4 times higher than in women. The risk of HT was found to be 2.9 times higher in the group with insulin resistance. While there was a positive relationship between systolic blood pressure and CRP and HOMA-IR, no relationship was found with diastolic blood pressure. Metabolic inflammation and insulin resistance may be in the etiology of systolic HT rather than diastolic HT. Obesity-related hypertension is more common in men, with increasing age, and in those with insulin resistance. Systolic blood pressure may be associated with insulin resistance.

Keywords

• obesity-related hypertension
• systolic/diastolic hypertension
• insulin resistance
• metabolic inflammation

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