EN
Virtually reducing pain: A systematic and meta-analysis on the efficiency of virtual reality in orofacial pain management
Abstract
Virtual Reality (VR), a computer technology that simulates a three-dimensional artificial environment and acts on the perception of pain through the effect on attention, emotion, concentration and/or memory. The purpose of this study was to conduct a systematic review of literature comparing the effectiveness and analyse the efficacy of VR as a method for reducing pain levels in orofacial pain management. To evaluate the efficacy of Virtual Reality in Orofacial Pain Management as therapeutic alternative in Randomized Controlled Trials. A systematic review and meta-analysis was conducted according to PRISMA 2020 guidelines, to quantify the association between orofacial pain and VR effectiveness as management. MEDLINE, EMBASE, Cochrane, Scopus, Web of Science, CINAHL, Google Scholar and manual search was systematically searched till 9th February 2025. Five studies were selected and evaluated in depth. The statistical evaluation was done with a Forest plot with overall effect size at 0.25. The test for overall effect as represented by z-score was 0.25, thus 0.25 standard deviations above the mean with a P-value of 0.81 at 95% confidence interval. The heterogeneity measured as τ2 was 0.87 and thus minimal. Virtual Reality as a part of pain management is about tricking the eyes and ears to change the working of the brain. From an enhanced treatment experience to a better psychological profile of the treatment after procedure, this add on to therapeutic protocol has a high potential on the utility front. The positive potential in the use of virtual reality in the management of orofacial pain has added backing from the data review and meta-analysis.
Keywords
Supporting Institution
SRM Dental College
Ethical Statement
This manuscript is a systematic review and meta-analysis. Therefore, it uses data from published sources.
References
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Details
Primary Language
English
Subjects
Pain, Allied Health and Rehabilitation Science (Other)
Journal Section
Review
Authors
Publication Date
December 31, 2025
Submission Date
May 9, 2025
Acceptance Date
September 9, 2025
Published in Issue
Year 2025 Volume: 42 Number: 4
APA
Aniyan, Y., Ganesan, A., Cl, K., & Murugan, A. J. (2025). Virtually reducing pain: A systematic and meta-analysis on the efficiency of virtual reality in orofacial pain management. Deneysel Ve Klinik Tıp Dergisi, 42(4), 466-472. https://izlik.org/JA29ST67LL
AMA
1.Aniyan Y, Ganesan A, Cl K, Murugan AJ. Virtually reducing pain: A systematic and meta-analysis on the efficiency of virtual reality in orofacial pain management. J. Exp. Clin. Med. 2025;42(4):466-472. https://izlik.org/JA29ST67LL
Chicago
Aniyan, Yesoda, Anuradha Ganesan, Krithika Cl, and Arul Jothi Murugan. 2025. “Virtually Reducing Pain: A Systematic and Meta-Analysis on the Efficiency of Virtual Reality in Orofacial Pain Management”. Deneysel Ve Klinik Tıp Dergisi 42 (4): 466-72. https://izlik.org/JA29ST67LL.
EndNote
Aniyan Y, Ganesan A, Cl K, Murugan AJ (December 1, 2025) Virtually reducing pain: A systematic and meta-analysis on the efficiency of virtual reality in orofacial pain management. Deneysel ve Klinik Tıp Dergisi 42 4 466–472.
IEEE
[1]Y. Aniyan, A. Ganesan, K. Cl, and A. J. Murugan, “Virtually reducing pain: A systematic and meta-analysis on the efficiency of virtual reality in orofacial pain management”, J. Exp. Clin. Med., vol. 42, no. 4, pp. 466–472, Dec. 2025, [Online]. Available: https://izlik.org/JA29ST67LL
ISNAD
Aniyan, Yesoda - Ganesan, Anuradha - Cl, Krithika - Murugan, Arul Jothi. “Virtually Reducing Pain: A Systematic and Meta-Analysis on the Efficiency of Virtual Reality in Orofacial Pain Management”. Deneysel ve Klinik Tıp Dergisi 42/4 (December 1, 2025): 466-472. https://izlik.org/JA29ST67LL.
JAMA
1.Aniyan Y, Ganesan A, Cl K, Murugan AJ. Virtually reducing pain: A systematic and meta-analysis on the efficiency of virtual reality in orofacial pain management. J. Exp. Clin. Med. 2025;42:466–472.
MLA
Aniyan, Yesoda, et al. “Virtually Reducing Pain: A Systematic and Meta-Analysis on the Efficiency of Virtual Reality in Orofacial Pain Management”. Deneysel Ve Klinik Tıp Dergisi, vol. 42, no. 4, Dec. 2025, pp. 466-72, https://izlik.org/JA29ST67LL.
Vancouver
1.Yesoda Aniyan, Anuradha Ganesan, Krithika Cl, Arul Jothi Murugan. Virtually reducing pain: A systematic and meta-analysis on the efficiency of virtual reality in orofacial pain management. J. Exp. Clin. Med. [Internet]. 2025 Dec. 1;42(4):466-72. Available from: https://izlik.org/JA29ST67LL
