Drug transport to the brain

S.sırrı Bilge; Arzu Erdal Ağrı; Bahar Akyüz

Drug transport to the brain

Year 2016, Volume: 33 Issue: 2, 0 - 0, 16.06.2016

S.sırrı Bilge , Arzu Erdal Ağrı Bahar Akyüz

https://izlik.org/JA85WD92WX

Abstract

Blood brain barrier (BBB) is a special cellular system that enables the nervous system to maintain in brains homeostasis by allowing the essential materials to pass while denying harmful substances. All of the drugs with high molecular weight and 98% of the drugs with low molecular weight cannot pass through the BBB. Only a few high liposoluble molecules, which have smaller than 500 Da molecular weight, can pass through the BBB. Thus, a great number of central nervous system diseases do not respond to this kind of drugs. However, in order to effectively treat a great quantity of neurological diseases there is increasing necessity for drugs which can pass through the central nervous system. In conclusion, in recent years, studies aimed new strategies for the passage of the drugs with high molecular weight through the brain have been carried out.

Keywords

Blood brain barrier , brain delivery; drug transport

Year 2016, Volume: 33 Issue: 2, 0 - 0, 16.06.2016

S.sırrı Bilge , Arzu Erdal Ağrı Bahar Akyüz

https://izlik.org/JA85WD92WX

Abstract

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Details

Authors	S.sırrı Bilge Arzu Erdal Ağrı This is me Bahar Akyüz
Submission Date	November 30, 2015
Publication Date	June 16, 2016
IZ	https://izlik.org/JA85WD92WX
Published in Issue	Year 2016 Volume: 33 Issue: 2

Cite

APA	Bilge, S., Erdal Ağrı, A., & Akyüz, B. (2016). Drug transport to the brain. Deneysel Ve Klinik Tıp Dergisi, 33(2). https://izlik.org/JA85WD92WX
AMA	1.Bilge S, Erdal Ağrı A, Akyüz B. Drug transport to the brain. J. Exp. Clin. Med. 2016;33(2). https://izlik.org/JA85WD92WX
Chicago	Bilge, S.sırrı, Arzu Erdal Ağrı, and Bahar Akyüz. 2016. “Drug Transport to the Brain”. Deneysel Ve Klinik Tıp Dergisi 33 (2). https://izlik.org/JA85WD92WX.
EndNote	Bilge S, Erdal Ağrı A, Akyüz B (June 1, 2016) Drug transport to the brain. Deneysel ve Klinik Tıp Dergisi 33 2
IEEE	[1]S. Bilge, A. Erdal Ağrı, and B. Akyüz, “Drug transport to the brain”, J. Exp. Clin. Med., vol. 33, no. 2, June 2016, [Online]. Available: https://izlik.org/JA85WD92WX
ISNAD	Bilge, S.sırrı - Erdal Ağrı, Arzu - Akyüz, Bahar. “Drug Transport to the Brain”. Deneysel ve Klinik Tıp Dergisi 33/2 (June 1, 2016). https://izlik.org/JA85WD92WX.
JAMA	1.Bilge S, Erdal Ağrı A, Akyüz B. Drug transport to the brain. J. Exp. Clin. Med. 2016;33. Available at https://izlik.org/JA85WD92WX.
MLA	Bilge, S.sırrı, et al. “Drug Transport to the Brain”. Deneysel Ve Klinik Tıp Dergisi, vol. 33, no. 2, June 2016, https://izlik.org/JA85WD92WX.
Vancouver	1.S.sırrı Bilge, Arzu Erdal Ağrı, Bahar Akyüz. Drug transport to the brain. J. Exp. Clin. Med. [Internet]. 2016 Jun. 1;33(2). Available from: https://izlik.org/JA85WD92WX