Case Report

Two Different Regenerative Injections in Patients Diagnosed with Secondary Hip Osteoarthritis: A Report of Two Cases

Volume: 38 Number: 2 April 3, 2021
EN

Two Different Regenerative Injections in Patients Diagnosed with Secondary Hip Osteoarthritis: A Report of Two Cases

Abstract

Non-surgical treatment options are limited in hip osteoarthritis secondary to developmental dysplasia of the hip (DDH). Treatment of Autologous Conditioned Serum (ACS) is based on the high level of anti-inflammatory cytokine production of leukocytes in peripheral blood. It is an effective treatment option which contains the cytokines and the growth factors. Platelet Rich Plasma (PRP) is a form of treatment that stimulates natural healing steps through growth factors in platelets. In this case report we aimed to present the results of ACS and PRP injection in two patients who developed secondary coxarthrosis after DDH surgery. At the 1-year follow-up examination, patient’s functional scores improved and requirement for non-steroid anti- inflammatory drugs had significantly reduced. Regenerative injections either autologous conditioned serum or platelet rich plasma treatments are safe and effective treatments and can be recommended particularly for cases of secondary hip osteoarthritis associated with DDH.

Keywords

References

  1. Referans1: Abate, M., et al., 2008. Viscosupplementation with hyaluronic acid in hip osteoarthritis (a review). Ups J Med Sci. 113, 261-77.
  2. Referans2: Alsousou, J., et al., 2009. The biology of platelet-rich plasma and its application in trauma and orthopaedic surgery: a review of the literature. J Bone Joint Surg Br. 91, 987-96.
  3. Referans3: Andia, I., Sanchez, M., Maffulli, N., 2012. Joint pathology and platelet-rich plasma therapies. Expert Opin Biol Ther. 12, 7-22.
  4. Referans4: Arend, W.P., et al., 1998. Interleukin-1 receptor antagonist: role in biology. Annu Rev Immunol. 16, 27-55.
  5. Referans5: Auw Yang, K.G., et al., 2008. Autologous interleukin-1 receptor antagonist improves function and symptoms in osteoarthritis when compared to placebo in a prospective randomized controlled trial. Osteoarthritis Cartilage. 16, 498-505.
  6. Referans6: Baltzer, A.W., et al., 2009. Autologous conditioned serum (Orthokine) is an effective treatment for knee osteoarthritis. Osteoarthritis Cartilage. 17, 152-60.
  7. Referans7: Baltzer, A.W., et al., 2013. A new treatment for hip osteoarthritis: clinical evidence for the efficacy of autologous conditioned serum. Orthop Rev (Pavia). 5, 59-64.
  8. Referans8: Dallari, D., et al., 2016. Ultrasound-Guided Injection of Platelet-Rich Plasma and Hyaluronic Acid, Separately and in Combination, for Hip Osteoarthritis: A Randomized Controlled Study. Am J Sports Med. 44, 664-71.

Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Case Report

Authors

İsmail Büyükceran This is me
Türkiye

Publication Date

April 3, 2021

Submission Date

April 14, 2020

Acceptance Date

December 16, 2020

Published in Issue

Year 2021 Volume: 38 Number: 2

APA
Say, F., Büyükceran, İ., & Coşkun, S. (2021). Two Different Regenerative Injections in Patients Diagnosed with Secondary Hip Osteoarthritis: A Report of Two Cases. Deneysel Ve Klinik Tıp Dergisi, 38(2), 204-207. https://izlik.org/JA39XE49UU
AMA
1.Say F, Büyükceran İ, Coşkun S. Two Different Regenerative Injections in Patients Diagnosed with Secondary Hip Osteoarthritis: A Report of Two Cases. J. Exp. Clin. Med. 2021;38(2):204-207. https://izlik.org/JA39XE49UU
Chicago
Say, Ferhat, İsmail Büyükceran, and Sina Coşkun. 2021. “Two Different Regenerative Injections in Patients Diagnosed With Secondary Hip Osteoarthritis: A Report of Two Cases”. Deneysel Ve Klinik Tıp Dergisi 38 (2): 204-7. https://izlik.org/JA39XE49UU.
EndNote
Say F, Büyükceran İ, Coşkun S (April 1, 2021) Two Different Regenerative Injections in Patients Diagnosed with Secondary Hip Osteoarthritis: A Report of Two Cases. Deneysel ve Klinik Tıp Dergisi 38 2 204–207.
IEEE
[1]F. Say, İ. Büyükceran, and S. Coşkun, “Two Different Regenerative Injections in Patients Diagnosed with Secondary Hip Osteoarthritis: A Report of Two Cases”, J. Exp. Clin. Med., vol. 38, no. 2, pp. 204–207, Apr. 2021, [Online]. Available: https://izlik.org/JA39XE49UU
ISNAD
Say, Ferhat - Büyükceran, İsmail - Coşkun, Sina. “Two Different Regenerative Injections in Patients Diagnosed With Secondary Hip Osteoarthritis: A Report of Two Cases”. Deneysel ve Klinik Tıp Dergisi 38/2 (April 1, 2021): 204-207. https://izlik.org/JA39XE49UU.
JAMA
1.Say F, Büyükceran İ, Coşkun S. Two Different Regenerative Injections in Patients Diagnosed with Secondary Hip Osteoarthritis: A Report of Two Cases. J. Exp. Clin. Med. 2021;38:204–207.
MLA
Say, Ferhat, et al. “Two Different Regenerative Injections in Patients Diagnosed With Secondary Hip Osteoarthritis: A Report of Two Cases”. Deneysel Ve Klinik Tıp Dergisi, vol. 38, no. 2, Apr. 2021, pp. 204-7, https://izlik.org/JA39XE49UU.
Vancouver
1.Ferhat Say, İsmail Büyükceran, Sina Coşkun. Two Different Regenerative Injections in Patients Diagnosed with Secondary Hip Osteoarthritis: A Report of Two Cases. J. Exp. Clin. Med. [Internet]. 2021 Apr. 1;38(2):204-7. Available from: https://izlik.org/JA39XE49UU