Research Article

Can asymptomatic Chron’s disease be diagnosed in patients with iron deficiency anemia by CT-enterograhpy?

Volume: 38 Number: 2s March 18, 2021
EN

Can asymptomatic Chron’s disease be diagnosed in patients with iron deficiency anemia by CT-enterograhpy?

Abstract

It is difficult to diagnose Crohn's disease in the asymptomatic period. The aim of this study is to evaluate the diagnostic utility of CT enterography (CTE) in the diagnosis of asymptomatic Crohn's disease (CD) with small intestine involment in patients with iron deficiency anemia (IDA). 250 patients who underwent CTE examination between 2017 and 2018 were retrospectively scanned. 45 patients who had endoscopic examinations and diagnosed with IDA were included in the study. While one or more pathological findings to explain IDA were observed in 31 (68%) patients with endoscopic examinations, findings that could be explained as CD sequelae were observed in 4 (8.8%) patients. No lesions were observed by CTE in 10 (22.2%) patients. Diagnosis is difficult in mild forms of Crohn’s disease or in periods of remission. In this period, CTE can contribute to the diagnosis as it can also show extraluminal findings.

Keywords

References

  1. Berther R, Patak MA, Eckhardt B, Erturk SM, Zollikofer CL., 2008. Comparison of neutral oral contrast versus positive oral contrast medium in abdominal multidetector CT. Eur Radiol., 18(9):1902-1909
  2. Beutler E, Waalen J., 2006. The definition of anemia: what is the lower limit of normal of the blood hemoglobin concentration? Blood, 107:1747-50.
  3. Bodily KD, Fletcher JG, Solem CA, Johnson CD, Fidler JL, Barlow JM, Bruesewitz MR, McCollough CH, Sandborn WJ, Loftus Jr EV, Harmsen WS, Crownhart BS., 2006. Crohn disease: mural attenuation and thickness at contrastenhanced CT enterography—correlation with endoscopic and histologic findings of inflammation. Radiology, 238:505–516
  4. Booya F, Fletcher JG, Huprich JE, Barlow, JM, Johnson CD, Fidler JL, Solem CA, Sandborn WJ, Loftus Jr EV, Harmsen WS, 2006. Active Crohn Disease: CT Findings and Interobserver Agreement for Enteric Phase CT Enterography. Radiology, 241:787
  5. Bruining DH, Loftus EV., 2006. Evolving diagnostic strategies for inflammatory bowel disease. Curr Gastroenterol Rep., 8:478.
  6. Farmer RG, Whelan G, Fazio VW., 1985. Long-term follow-up of patients with Crohn’s disease. Relationship between the clinical pattern and prognosis. Gastroenterology, 88:1818
  7. Hardwick RH, Armstrong CP., 1997. Synchronous upper and lower gastrointestinal endoscopy is an effective method of investigating iron-deficiency anemia. Br J Surg., 84:1725-8.
  8. Looker AC, Dalman PR, Carroll MD, Gunter EW, Johnson CL., 1997. Prevalance of iron deficiency anemia in United States. JAMA, 277:973-6.

Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Publication Date

March 18, 2021

Submission Date

September 7, 2020

Acceptance Date

November 6, 2020

Published in Issue

Year 2021 Volume: 38 Number: 2s

APA
Avcıoğlu, U., & İdil Soylu, A. (2021). Can asymptomatic Chron’s disease be diagnosed in patients with iron deficiency anemia by CT-enterograhpy? Deneysel Ve Klinik Tıp Dergisi, 38(2s), 71-73. https://izlik.org/JA63SM34UW
AMA
1.Avcıoğlu U, İdil Soylu A. Can asymptomatic Chron’s disease be diagnosed in patients with iron deficiency anemia by CT-enterograhpy? J. Exp. Clin. Med. 2021;38(2s):71-73. https://izlik.org/JA63SM34UW
Chicago
Avcıoğlu, Ufuk, and Ayşegül İdil Soylu. 2021. “Can Asymptomatic Chron’s Disease Be Diagnosed in Patients With Iron Deficiency Anemia by CT-Enterograhpy?”. Deneysel Ve Klinik Tıp Dergisi 38 (2s): 71-73. https://izlik.org/JA63SM34UW.
EndNote
Avcıoğlu U, İdil Soylu A (March 1, 2021) Can asymptomatic Chron’s disease be diagnosed in patients with iron deficiency anemia by CT-enterograhpy? Deneysel ve Klinik Tıp Dergisi 38 2s 71–73.
IEEE
[1]U. Avcıoğlu and A. İdil Soylu, “Can asymptomatic Chron’s disease be diagnosed in patients with iron deficiency anemia by CT-enterograhpy?”, J. Exp. Clin. Med., vol. 38, no. 2s, pp. 71–73, Mar. 2021, [Online]. Available: https://izlik.org/JA63SM34UW
ISNAD
Avcıoğlu, Ufuk - İdil Soylu, Ayşegül. “Can Asymptomatic Chron’s Disease Be Diagnosed in Patients With Iron Deficiency Anemia by CT-Enterograhpy?”. Deneysel ve Klinik Tıp Dergisi 38/2s (March 1, 2021): 71-73. https://izlik.org/JA63SM34UW.
JAMA
1.Avcıoğlu U, İdil Soylu A. Can asymptomatic Chron’s disease be diagnosed in patients with iron deficiency anemia by CT-enterograhpy? J. Exp. Clin. Med. 2021;38:71–73.
MLA
Avcıoğlu, Ufuk, and Ayşegül İdil Soylu. “Can Asymptomatic Chron’s Disease Be Diagnosed in Patients With Iron Deficiency Anemia by CT-Enterograhpy?”. Deneysel Ve Klinik Tıp Dergisi, vol. 38, no. 2s, Mar. 2021, pp. 71-73, https://izlik.org/JA63SM34UW.
Vancouver
1.Ufuk Avcıoğlu, Ayşegül İdil Soylu. Can asymptomatic Chron’s disease be diagnosed in patients with iron deficiency anemia by CT-enterograhpy? J. Exp. Clin. Med. [Internet]. 2021 Mar. 1;38(2s):71-3. Available from: https://izlik.org/JA63SM34UW