EN
Management of the Gastrointestinal System Bleeding Caused by Direct-Acting Oral Anticoagulants
Abstract
Direct-acting oral anticoagulants include dabigatran, which is a thrombin inhibitor, and rivaroxaban, apixaban, and edoxaban, which are anti-Xa agents. These are administered in the secondary prophylaxis and treatment of venous thromboembolism (VTE) and pulmonary embolism (PE), in the prophylaxis of VTE that may develop after major elective orthopedic surgery, in reducing stroke and systemic embolism that may occur in non-valvular atrial fibrillation, whereas its use in acute coronary syndrome is still controversial. Although it is specified that direct-acting oral anticoagulants are as effective as heparin therapy and reduce the risk of bleeding due to all causes, many important studies have also reported that they increase the risk of gastrointestinal system (GIS) bleeding.
Keywords
Supporting Institution
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Thanks
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References
- Abraham NS, Singh S, Alexander GC, Heien H, Haas LR, Crown W, et al., 2015. Comparative risk of gastrointestinal bleeding with dabigatran, rivaroxaban, and warfarin: population based cohort study. BMJ. 350:h1857.
Details
Primary Language
English
Subjects
Health Care Administration
Journal Section
Review
Publication Date
March 18, 2021
Submission Date
September 10, 2020
Acceptance Date
November 18, 2020
Published in Issue
Year 2021 Volume: 38 Number: 2s
APA
Acar, Ş., & Eminler, A. (2021). Management of the Gastrointestinal System Bleeding Caused by Direct-Acting Oral Anticoagulants. Deneysel Ve Klinik Tıp Dergisi, 38(2s), 33-37. https://izlik.org/JA37US34RP
AMA
1.Acar Ş, Eminler A. Management of the Gastrointestinal System Bleeding Caused by Direct-Acting Oral Anticoagulants. J. Exp. Clin. Med. 2021;38(2s):33-37. https://izlik.org/JA37US34RP
Chicago
Acar, Şencan, and Ahmet Eminler. 2021. “Management of the Gastrointestinal System Bleeding Caused by Direct-Acting Oral Anticoagulants”. Deneysel Ve Klinik Tıp Dergisi 38 (2s): 33-37. https://izlik.org/JA37US34RP.
EndNote
Acar Ş, Eminler A (March 1, 2021) Management of the Gastrointestinal System Bleeding Caused by Direct-Acting Oral Anticoagulants. Deneysel ve Klinik Tıp Dergisi 38 2s 33–37.
IEEE
[1]Ş. Acar and A. Eminler, “Management of the Gastrointestinal System Bleeding Caused by Direct-Acting Oral Anticoagulants”, J. Exp. Clin. Med., vol. 38, no. 2s, pp. 33–37, Mar. 2021, [Online]. Available: https://izlik.org/JA37US34RP
ISNAD
Acar, Şencan - Eminler, Ahmet. “Management of the Gastrointestinal System Bleeding Caused by Direct-Acting Oral Anticoagulants”. Deneysel ve Klinik Tıp Dergisi 38/2s (March 1, 2021): 33-37. https://izlik.org/JA37US34RP.
JAMA
1.Acar Ş, Eminler A. Management of the Gastrointestinal System Bleeding Caused by Direct-Acting Oral Anticoagulants. J. Exp. Clin. Med. 2021;38:33–37.
MLA
Acar, Şencan, and Ahmet Eminler. “Management of the Gastrointestinal System Bleeding Caused by Direct-Acting Oral Anticoagulants”. Deneysel Ve Klinik Tıp Dergisi, vol. 38, no. 2s, Mar. 2021, pp. 33-37, https://izlik.org/JA37US34RP.
Vancouver
1.Şencan Acar, Ahmet Eminler. Management of the Gastrointestinal System Bleeding Caused by Direct-Acting Oral Anticoagulants. J. Exp. Clin. Med. [Internet]. 2021 Mar. 1;38(2s):33-7. Available from: https://izlik.org/JA37US34RP
