Skin reaction related to povidone iodine use

Abstract

Nowadays, 10 % povidone-idodine is a topical antiseptic solution that commonly used in surgical areas’s sterilization, wound cleaning, daily wound dressing. Serious complications can be induced by povidone iodine when it is not used carefully and adequate proportion.Povidone- iodine induced chemical skin reactions is the one of the these serious complications. Given the widespread use of povidone-iodine, clinicians need to be aware of this possible adverse drug reaction and of preventive cautions. This report presents two cases about povidone-iodine related skin reaction ( these reactions are also called as chemical burns or chemical skin reactions ) which are encountered in our hospital(Ondokuz Mayıs University, SAMSUN, TURKEY) to point this important issue.

Keywords

• Antiseptics
• povidon iodine
• contact dermatitis
• skin reactions

References

1. Referans1. Shelanski H, Shelanski M. PVP-iodine: history, toxicity and therapeutic uses. J Int Coll Surg 1956;25:727–34.
2. Referans2. M.A. Reyazulla, A.L. Gopinath, N Vaibhav, R P Raut. An unusual complication of late onset allergic contact dermatitis to povidone iodine in Oral & Maxillofacial Surgery – A report of 2 cases. Eur Ann Allergy Clin Immunol Vol 46, N4; 157-159, 2014.
3. Referans3. https://www.wellrx.com/povidone-iodine/monographs.
4. Referans4. Gönül Eser Mete, Z. Serpil Ustalar Özgen, Buket Çiğdem, Olcay İsbir. Povidon İyot ile Cilt Hazırlığı Sonrası Gelişen Cilt Reaksiyonları. Sağlık Bilimleri Fakültesi Hemşirelik Dergisi 2009; 52–56.
5. Referans5. Marks JG. Allergic contact dermatitis to povidone-iodine. J Am Acad Dermatol 1982; 6, 473-5.
6. Referans6. Vandergriff MD et al. Irrıtant contact dermatitis from exposure to povidone-iodine may resemble toxic epidermal necrolysis. Dermatology Online Journal 2006; 12 (7):12.
7. Referans7. Iijima S, Kuramochi M. Investigation of irritant skin reaction by 10% povidone-iodine solution after surgery. Dermatology 2002;204(suppl 1):103–8.
8. Referans8. Kara A, Tezer H, Devrim I, Cengiz AB, Secmeer G. Chemical burn: A risk with outdated povidone iodine. Pediatr Dermatol 2007;24:449-50.

9. Referans9. Constance H Katelaris, William B Smith, Iodine allergy label is misleading. Australian Prescriber 2009; Volume 32 , Number 5.
10. Referans10. Donna O. Lowe, Sandra R. Knowles, Elizabeth A Weber, Craig J Railton, Neil H Shear. Povidone-Iodine–Induced Burn: Case Report and Review of the Literature. Pharmacotherapy 2006;26(11):1641–1645).
11. Referans11. Yuan-Cheng Chiang, Tsan-Shiun Lin, Ming-Chung Yeh. Povidone-iodine-related burn under the tourniquet of a child e a case report and literature review. Journal of Plastic, Reconstructive & Aesthetic Surgery 2011; 64, 412e415.
12. Referans12. Zamora JL. Chemical and microbiologic characteristics and toxicity of povidone-iodine solutions. Am J Surg 1986; 151: 400–6.
13. Referans13. Nahlieli O, Baruchin AM, Levi D, Shapira Y, Yoffe B. Povidone-iodine related burns. Burns 2001; 27:185e8.
14. Referans14. Ellenhorn JD et al. Paint-only isequivalent to scrub-and-paint in preoperative preparation of abdominal surgery sites. J Am Coll Surg 2005; 201 (5):737-41.