A rare case of synchronous genital carcinoma involving endometrium and unilateral fallopian tube in a 24 years old patient

Abstract

Multifocal synchronous development of malignancies of the female genital tract is a rare occurrence and less than 3% of primary malignancies of this region is synchronous. Although the simultaneous presentation of endometrial and ovarian carcinoma of the endometrioid type is well described little is known about a similar phenomenon involving the endometrium and fallopian tube. The relationship between the synchronous tumours is uncertain. More illuminating studies are being conducted on the relationship between synchronized endometrial and ovarian carcinomas in recent studies.This case is about synchronous genital carcinoma involving endometrium and unilateral fallopian tube in a 24 years old patient.

Keywords

• synchronous tumors
• endometrioid carcinoma
• endometrial carcinoma
• fallopian tube carcinoma.

References

1. 1. Swarup A, Manjunath R, Sudha H. A Rare Case of Synchronous Genital Carcinoma Involving the Endocervix and Bilateral Fallopian Tubes. J South Asian Feder Obs Gynae 2011; 3 (2):106-108.
2. 2. Kan O, Alkilic A, Turgay B, Gemici A, Atabekoglu CS. Triple Synchronous Malignancies in Genital Tract; Primary Endometrial, Ovarian and Fallopian Tube Carcinoma: A Case Report. Journal of Clinical and Diagnostic Research: JCDR. 2017;11(1): QD01-QD02. doi:10.7860/JCDR/2017/22003.9138.
3. 3. Ulbright T, Roth L. Metastatic and independent cancers of the endometrium and ovary: A clinicopathologic study of 34 cases. Hum Pathol. 1985; 16:28-34.
4. 4. Williams MG, Bandera EV, Demissie K, Rodríguez-Rodríguez L. Synchronous primary ovarian and endometrial cancers: A population-based assessment of survival. Obstet Gynaecol. 2009;113(4):783-89.
5. 5. Chiang YC, Chen CA, Huang CY, Hsieh CY, Cheng WF. Synchronous primary cancers of the endometrium and ovary. Int J Gynaecol Cancer. 2008; 18:159–64.
6. 6. Chen S, Parmigiani G. Meta-analysis of BRCA1 and BRCA2 penetrance. J Clin Oncol. 2007;25(11):1329-33.
7. 7. Dunlop MG, Farrington SM, Carothers AD, Wyllie AH, Sharp L, Burn J, et al.Cancer risk associated with germline DNA mismatch repair gene mutations. Hum Mol Genet. 1997; 10:105–1