The effects of methanolic plant extract on the cardiovascular system of induced preeclampticWistar rats

Abstract

This work investigated the effects of methanolic plant extract on the cardiovascular system of induced preeclamptic Wistar rats. Preeclampsia is associated with increase in high blood pressure and proteinuria. Studies have shown the only medically acceptable treatment is the removal of the fetus from the mother, however there is considerable lack of studies done to show the use of herbal medicine in the treatment and management of preeclampsia. This study reveals the use of plant extract and its effect on cardiovascular system. Three plants extract; Jatropha curcas, Alchornea cordifolia andSecamone afzelii were used for the study. Results showed that there were no observable lesion or abnormally in the cardiovascular system and the use of all three plant extracts significantly reduced blood pressure and proteinuria, thus indicating a reduction of preeclampsia from severe to mild.

Keywords

• preeclampsia
• highblood pressure
• proteinuria
• herbal medicine
• Jatropha curcas
• Alchornea cordifolia
• Secamone afzelii

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