Abstract
Gastrointestinal Complications of Nonsteroidal Antiinflammatory Drugs
%/ Nonsteroidal anti-inflammatory drugs (NSAİD) are popular by virtue of their analgesic, anti-inflammatory, antipyretic, and platelet inhibitoiy actions. These drugs inhibit the intracellular cyclooxygenase enzyme system, thus blocking the production of various prostaglandin compounds. The most common side effect of NSAİD therapy relates to gast¬rointestinal damage. A wide variety of disorders may develop in patients taking NSAlDs, ranging from minor dyspepsia to life-threatening ulcer bleeding or perforation. Treatment involves stopping the drug if at all possible and then instituting more specific therapy de¬pending on the anatomic area that has been injured.
Nonsteroidal antiinflamatuar ilaçlar (NSAll) analjezik, antiinflamatuar, antipiretik ve trom-bosit fonksiyonlarını inhibe edici özellikleri olan ilaçlardır. Bu ilaçlar hücre içi siklooksijenaz enzim sistemini inhibe ederek prostaglandin bileşiklerinin sentezini bloke ederler. NSAll tedavisinin en sık görülen yan etkisi gastrointestinal sistem üzerinedir. NSAll alan hastalarda minör dispepsiden hayatı tehdit edici kanama ve perforasyonlara kadar uza¬nan bir dizi komplikasyon gelişebilir. Tedavide önce ilaç kesilir, daha sonra tutulan anato¬mik bölgeye göre spesifik tedavi uygulanır.
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| Primary Language | English |
|---|---|
| Journal Section | Basic Medical Sciences |
| Authors | |
| Publication Date | December 22, 2009 |
| Submission Date | December 3, 2009 |
| Published in Issue | Year 1994 Volume: 11 Issue: 2 |
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