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Visualization Of A Bronchial Carcinoma With İts Soft Tissue And Bone Metastasis Using TC99M-Tetrofosmin

Year 1996, Volume: 13 Issue: 1, - , 23.12.2009

Abstract

Increased uptake of l,2-bis[bls(2-ethoxyethyl) phospino] ethane (Tc-99m tetrofosmin) in tumor as well as its soft tissue and bone metastasis was demonstrated in a patient with poorly differentiated squamous cell carcinoma of the lung. 740 MBq (20 mCi) of Tc-99m tetrofosmin was injected intravenously. Following an initial dynamic acquisition of 30 mi-nutes, static images were obtained at 30-35 and 85-90 minutes post injection (p.i.). Time to peak concentration in all three lesions was achieved within the first two minutes. Le¬sion to contralateral normal tissue uptake ratios of tumor, bone and soft tissue metasta¬sis at 30-35 minutes and at 85-90 minutes p.i. were 1.62, 1.41, 3.11 and 1.43, 1.22, 1.80 respectively. We conclude that accumulation of Tc-99m tetrofosmin in tumor and metastasis at once is an encouraging finding and justifies further investigations using this agent in the domain of tumor imaging.



Az diferansiye epidermoid karsinomalı bir hastada tümörün yanısıra yumuşak doku ve kemik metastazlarında artmış l,2-bis[bis(2-ethoxyethyl) phospino] ethane (Tc-99m Tetro-fosmin) akümülasyonu olduğu gösterilmiştir. 740 MBq (20 mCi) Tc-99m Tetrofosmin intravenöz yoldan enjekte edildikten sonra 30 dakikalık dinamik, 30-35. ve 85-90. dakika-larda statik görüntüler elde edilmiş, maksimum konsantrasyon pikine her üç lezyonda da ilk iki dakika içerisinde ulaşılmıştır. Enjeksiyon sonrası 30-35. ve 85-90 cı dakikalarda tümör, kemik ve yumuşak doku metastazlannda lezyon/kontralateral normal doku tutu¬lum oranları 1.62, 1.41, 3.11 ve 1.43, 1.22,1.80 olarak saptanmıştır. Tc-99m Tetrofosmin'in tümörün yanısıra metastazlarında da akümüle olması, bu ajan ile tümör görüntüleme alanında yapılacak daha ileri çalışmaların gerekliliğini desteklemektir.

Year 1996, Volume: 13 Issue: 1, - , 23.12.2009

Abstract

There are 0 citations in total.

Details

Primary Language English
Journal Section Basic Medical Sciences
Authors

T. Başoğlu This is me

C. Çoşkun This is me

İ. Bernay This is me

M. Şahin This is me

A. Koparan This is me

L. Erkan This is me

Publication Date December 23, 2009
Submission Date December 13, 2009
Published in Issue Year 1996 Volume: 13 Issue: 1

Cite

APA Başoğlu, T., Çoşkun, C., Bernay, İ., Şahin, M., et al. (2009). Visualization Of A Bronchial Carcinoma With İts Soft Tissue And Bone Metastasis Using TC99M-Tetrofosmin. Journal of Experimental and Clinical Medicine, 13(1). https://doi.org/10.5835/jecm.v13i1.659
AMA Başoğlu T, Çoşkun C, Bernay İ, Şahin M, Koparan A, Erkan L. Visualization Of A Bronchial Carcinoma With İts Soft Tissue And Bone Metastasis Using TC99M-Tetrofosmin. J. Exp. Clin. Med. December 2009;13(1). doi:10.5835/jecm.v13i1.659
Chicago Başoğlu, T., C. Çoşkun, İ. Bernay, M. Şahin, A. Koparan, and L. Erkan. “Visualization Of A Bronchial Carcinoma With İts Soft Tissue And Bone Metastasis Using TC99M-Tetrofosmin”. Journal of Experimental and Clinical Medicine 13, no. 1 (December 2009). https://doi.org/10.5835/jecm.v13i1.659.
EndNote Başoğlu T, Çoşkun C, Bernay İ, Şahin M, Koparan A, Erkan L (December 1, 2009) Visualization Of A Bronchial Carcinoma With İts Soft Tissue And Bone Metastasis Using TC99M-Tetrofosmin. Journal of Experimental and Clinical Medicine 13 1
IEEE T. Başoğlu, C. Çoşkun, İ. Bernay, M. Şahin, A. Koparan, and L. Erkan, “Visualization Of A Bronchial Carcinoma With İts Soft Tissue And Bone Metastasis Using TC99M-Tetrofosmin”, J. Exp. Clin. Med., vol. 13, no. 1, 2009, doi: 10.5835/jecm.v13i1.659.
ISNAD Başoğlu, T. et al. “Visualization Of A Bronchial Carcinoma With İts Soft Tissue And Bone Metastasis Using TC99M-Tetrofosmin”. Journal of Experimental and Clinical Medicine 13/1 (December 2009). https://doi.org/10.5835/jecm.v13i1.659.
JAMA Başoğlu T, Çoşkun C, Bernay İ, Şahin M, Koparan A, Erkan L. Visualization Of A Bronchial Carcinoma With İts Soft Tissue And Bone Metastasis Using TC99M-Tetrofosmin. J. Exp. Clin. Med. 2009;13. doi:10.5835/jecm.v13i1.659.
MLA Başoğlu, T. et al. “Visualization Of A Bronchial Carcinoma With İts Soft Tissue And Bone Metastasis Using TC99M-Tetrofosmin”. Journal of Experimental and Clinical Medicine, vol. 13, no. 1, 2009, doi:10.5835/jecm.v13i1.659.
Vancouver Başoğlu T, Çoşkun C, Bernay İ, Şahin M, Koparan A, Erkan L. Visualization Of A Bronchial Carcinoma With İts Soft Tissue And Bone Metastasis Using TC99M-Tetrofosmin. J. Exp. Clin. Med. 2009;13(1).