Olgu Bildirisi: Anjioinvazif Pulmoner Aspergillozis, BT VE MRG Bulguları

Year 2007, Volume: 24 Issue: 2, 62 - 66, 29.12.2009

M. Elmalı K. Bayrak M.S. Nural M. Ceyhan

Abstract

Angioinvasive Pulmonary Aspergillosis: CT and MRI Findings
Pulmonary aspergillosis is rare but potentially fatal infectious disease which is seen in immune compromised patients. Most of the cases are seen in patients who used chemotheraphy for hematological malignancies, bone marrow or solid organ transplant patients, patients with primer immune deficiency. The patient's immune system and the morphological changes in lungs determine course of infection. Angioinvasive pulmonary aspergillosis (invasive pulmonary aspergillosis) is usually seen in patients with neutropenia and late diagnosis can be fatal. With this case we discussed the radiological findings and the course of rapid growing pulmonary aspergillosis in a 5 year old patient with acute lymphoblastic leuchemia who applied with neutropenia, cough and high fever. Magnetic resonance imaging findings done to avoid the harmful affects of radiation because of lung roentgenograms and computerized tomography were also discussed.


Pulmoner aspergillozis immün sistemi baskılanmış hastalarda nadir, fakat potansiyel olarak fatal bir enfeksiyondur. Vakaların çoğunluğu hematolojik malignensiler nedeniyle kemotera-pi alan hastalar, kemik iliği veya solid organ transplantasyonu yapılan hastalar ve primer immün yetmezliği bulunan çocuklardır. Enfeksiyon tablosu hastanın immün sisteminin durumuna yada tutulan akciğerlerdeki yapısal değişiklilere bağlıdır. Anjioinvazif aspergillozis (invazif pulmoner aspergillozis) genellikle ciddi nötropenili hastalarda ortaya çıkan, tanısı gecikirse mortalitesi yüksek bir durumdur.
Öksürük ve ateş yüksekliği şikayeti nedeniyle baş vuran ve akut lenfoblastik lösemi nedeniyle takip edilen ciddi nötropenili 5 yaşındaki çocuk hastada, hızlı gelişen anjioinvasif as-pergillozisin radyolojik bulguları ve seyri tartışılmıştır. Ayrıca takipte sık akciğer grafisi ile bilgisayarlı tomografi ye bağlı radyasyon alımını azaltmak amacıyla değişik zamanlarda yapılan manyetik rezonans görüntüleme bulguları da literatürün ışığında tartışılmıştır.

Keywords

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