Olgu Sunumu
BibTex RIS Kaynak Göster

Neuroendocrine carcinoma of the rectum

Yıl 2017, Cilt: 34 Sayı: 4, 275 - 278, 10.10.2019

Öz




Neuroendocrine carcinoma (NEC) of the rectum is rare. Most patients have
metastatic disease at the time of diagnosis. These malignancies have a worse
prognosis compared with conventional adenocarcinoma, and there is no stan-
dard treatment protocol. We report herein a case of NEC of the rectum with
a short survival. A 60-year-old female was admitted to the emergency service
with jaundice, abdominal pain, back pain and confusion, without a history of
rectal bleeding. The imaging studies showed a rectal tumor, abdominal lymph-
adenopathies, and multiple liver and vertebral metastases. Rectal biopsy was
performed. The histopathologic findings were consistent with those of NEC.
Palliative radiotherapy was planned for the spinal metastases, but the patient
died before completing radiotherapy, within 1 month from diagnosis. In con-
clusion, these neoplasms show a dramatic course, particularly in metastatic pa-
tients, and there is a clear need for studies involving larger numbers of colon
and rectum NEC patients. 




Kaynakça

  • Aytac, E., Ozdemir, Y., Ozuner, G., 2014. Long term outcomes of neuroendocrine carcinomas (high-grade neuroendocrine tumors) of the colon, rectum, and anal canal. J. Visc. Surg. 151, 3-7.
  • Errasti, A.J., Espín, B.E., Reina, D.A., 2014. Rare tumors of the rectum. Narrative review. Cir. Esp. 92, 579-588.
  • Gould, V.E., Chejfec, G., 1978. Neuroendocrine carcinomas of the colon. Ultrastructural and biochemical evidence of their secretory function. Am. J. Surg. Pathol. 2, 31-38.
  • Kang, H., O’Connell, J.B., Leonardi, M.J., Maggard, M.A., McGory, M.L., Ko, C.Y., 2007. Rare tumors of the colon and rectum: a national review. Int. J. Colorectal. Dis. 22, 183-189.
  • Minocha, V., Shuja, S., Ali, R., Eid, E., 2014. Large cell neuroendocrine carcinoma of the rectum presenting with extensive metastatic disease. Case. Rep. Oncol. Med. 2014, 386379.
  • Miyamoto, H., Kurita, N., Nishioka, M., Ando, T., Tashiro, T., Hirokawa, M., Shimada, M., 2006. Poorly differentiated neuroendocrine cell carcinoma of the rectum: report of a case and literal review. J. Med. Invest. 53, 317-320.
  • Nojima, H., Seike, K., Kosugi, C., Shida, T., Koda, K., Oda, K., Kamata, S., Ishikura, H., Miyazaki, M., 2010. Advanced moderately differentiated neuroendocrine carcinoma of the rectum with favorable prognosis by postoperative chemoradiation. World. J. Surg. Oncol. 8, 29.
  • Okuyama, T., Korenaga, D., Tamura, S., Yao, T., Maekawa, S., Watanabe, A., Ikeda, T., Sugimachi, K., 1999. The effectiveness of chemotherapy with cisplatin and 5-fluorouracil for recurrent small cell neuroendocrine carcinoma of the rectum: report of a case. Surg. Today. 29, 165-169.
  • Öberg, K., Knigge, U., Kwekkeboom, D., Perren, A., ESMO Guidelines Working Group, 2012. Neuroendocrine gastro-entero- pancreatic tumors: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann. Oncol. 23, 124-130.
  • Shafqat, H., Ali, S., Salhab, M., Olszewski, A.J., 2015. Survival of patients with neuroendocrine carcinoma of the colon and rectum: a population-based analysis. Dis. Colon. Rectum. 58, 294-303.
  • Smith, J.D., Reidy, D.L., Goodman, K.A., Shia, J., Nash, G.M., 2014. A retrospective review of 126 high-grade neuroendocrine carcinomas of the colon and rectum. Ann. Surg. Oncol. 21, 2956-2962.
  • Sorbye, H., Welin, S., Langer, S.W., Vestermark, L.W., Holt, N., Osterlund, P., Dueland, S., Hofsli, E., Guren, M.G., Ohrling, K., Birkemeyer, E., Thiis-Evensen, E., Biagini, M., Gronbaek, H., Soveri, L.M., Olsen, I.H., Federspiel, B., Assmus, J., Janson, E.T., Knigge, U., 2013. Predictive and prognostic factors for treatment and survival in 305 patients with advanced gastrointestinal neuroendocrine carcinoma (WHO G3): the NORDIC NEC study. Ann. Oncol. 24, 152-160.
  • Vilallonga, R., Espín, B.E., López, C.M., Landolfi, S., Armengol, C.M., 2008. Neuroendocrine carcinomas of the colon and rectum. A unit’s experience over six years. Rev. Esp. Enferm. Dig. 100, 11-16.
  • Zhang, X., Ma, L., Bao, H., Zhang, J., Wang, Z., Gong, P., 2014. Clinical, pathological and prognostic characteristics of gastroenteropancreatic neuroendocrine neoplasms in China: a retrospective study. BMC. Endocr. Disord. 14, 54.
Yıl 2017, Cilt: 34 Sayı: 4, 275 - 278, 10.10.2019

Öz

Kaynakça

  • Aytac, E., Ozdemir, Y., Ozuner, G., 2014. Long term outcomes of neuroendocrine carcinomas (high-grade neuroendocrine tumors) of the colon, rectum, and anal canal. J. Visc. Surg. 151, 3-7.
  • Errasti, A.J., Espín, B.E., Reina, D.A., 2014. Rare tumors of the rectum. Narrative review. Cir. Esp. 92, 579-588.
  • Gould, V.E., Chejfec, G., 1978. Neuroendocrine carcinomas of the colon. Ultrastructural and biochemical evidence of their secretory function. Am. J. Surg. Pathol. 2, 31-38.
  • Kang, H., O’Connell, J.B., Leonardi, M.J., Maggard, M.A., McGory, M.L., Ko, C.Y., 2007. Rare tumors of the colon and rectum: a national review. Int. J. Colorectal. Dis. 22, 183-189.
  • Minocha, V., Shuja, S., Ali, R., Eid, E., 2014. Large cell neuroendocrine carcinoma of the rectum presenting with extensive metastatic disease. Case. Rep. Oncol. Med. 2014, 386379.
  • Miyamoto, H., Kurita, N., Nishioka, M., Ando, T., Tashiro, T., Hirokawa, M., Shimada, M., 2006. Poorly differentiated neuroendocrine cell carcinoma of the rectum: report of a case and literal review. J. Med. Invest. 53, 317-320.
  • Nojima, H., Seike, K., Kosugi, C., Shida, T., Koda, K., Oda, K., Kamata, S., Ishikura, H., Miyazaki, M., 2010. Advanced moderately differentiated neuroendocrine carcinoma of the rectum with favorable prognosis by postoperative chemoradiation. World. J. Surg. Oncol. 8, 29.
  • Okuyama, T., Korenaga, D., Tamura, S., Yao, T., Maekawa, S., Watanabe, A., Ikeda, T., Sugimachi, K., 1999. The effectiveness of chemotherapy with cisplatin and 5-fluorouracil for recurrent small cell neuroendocrine carcinoma of the rectum: report of a case. Surg. Today. 29, 165-169.
  • Öberg, K., Knigge, U., Kwekkeboom, D., Perren, A., ESMO Guidelines Working Group, 2012. Neuroendocrine gastro-entero- pancreatic tumors: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann. Oncol. 23, 124-130.
  • Shafqat, H., Ali, S., Salhab, M., Olszewski, A.J., 2015. Survival of patients with neuroendocrine carcinoma of the colon and rectum: a population-based analysis. Dis. Colon. Rectum. 58, 294-303.
  • Smith, J.D., Reidy, D.L., Goodman, K.A., Shia, J., Nash, G.M., 2014. A retrospective review of 126 high-grade neuroendocrine carcinomas of the colon and rectum. Ann. Surg. Oncol. 21, 2956-2962.
  • Sorbye, H., Welin, S., Langer, S.W., Vestermark, L.W., Holt, N., Osterlund, P., Dueland, S., Hofsli, E., Guren, M.G., Ohrling, K., Birkemeyer, E., Thiis-Evensen, E., Biagini, M., Gronbaek, H., Soveri, L.M., Olsen, I.H., Federspiel, B., Assmus, J., Janson, E.T., Knigge, U., 2013. Predictive and prognostic factors for treatment and survival in 305 patients with advanced gastrointestinal neuroendocrine carcinoma (WHO G3): the NORDIC NEC study. Ann. Oncol. 24, 152-160.
  • Vilallonga, R., Espín, B.E., López, C.M., Landolfi, S., Armengol, C.M., 2008. Neuroendocrine carcinomas of the colon and rectum. A unit’s experience over six years. Rev. Esp. Enferm. Dig. 100, 11-16.
  • Zhang, X., Ma, L., Bao, H., Zhang, J., Wang, Z., Gong, P., 2014. Clinical, pathological and prognostic characteristics of gastroenteropancreatic neuroendocrine neoplasms in China: a retrospective study. BMC. Endocr. Disord. 14, 54.
Toplam 14 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Case Report
Yazarlar

Alparslan Serarslan

Nilgun Ozbek Okumus Bu kişi benim

Filiz Karagoz Bu kişi benim

Mehmet Selim Nural Bu kişi benim

Bilge Gürsel Bu kişi benim

Deniz Meydan Bu kişi benim

Yayımlanma Tarihi 10 Ekim 2019
Gönderilme Tarihi 1 Şubat 2016
Kabul Tarihi 7 Nisan 2016
Yayımlandığı Sayı Yıl 2017 Cilt: 34 Sayı: 4

Kaynak Göster

APA Serarslan, A., Ozbek Okumus, N., Karagoz, F., Nural, M. S., vd. (2019). Neuroendocrine carcinoma of the rectum. Journal of Experimental and Clinical Medicine, 34(4), 275-278.
AMA Serarslan A, Ozbek Okumus N, Karagoz F, Nural MS, Gürsel B, Meydan D. Neuroendocrine carcinoma of the rectum. J. Exp. Clin. Med. Ekim 2019;34(4):275-278.
Chicago Serarslan, Alparslan, Nilgun Ozbek Okumus, Filiz Karagoz, Mehmet Selim Nural, Gürsel Bilge, ve Deniz Meydan. “Neuroendocrine Carcinoma of the Rectum”. Journal of Experimental and Clinical Medicine 34, sy. 4 (Ekim 2019): 275-78.
EndNote Serarslan A, Ozbek Okumus N, Karagoz F, Nural MS, Gürsel B, Meydan D (01 Ekim 2019) Neuroendocrine carcinoma of the rectum. Journal of Experimental and Clinical Medicine 34 4 275–278.
IEEE A. Serarslan, N. Ozbek Okumus, F. Karagoz, M. S. Nural, Gürsel B., ve D. Meydan, “Neuroendocrine carcinoma of the rectum”, J. Exp. Clin. Med., c. 34, sy. 4, ss. 275–278, 2019.
ISNAD Serarslan, Alparslan vd. “Neuroendocrine Carcinoma of the Rectum”. Journal of Experimental and Clinical Medicine 34/4 (Ekim 2019), 275-278.
JAMA Serarslan A, Ozbek Okumus N, Karagoz F, Nural MS, Gürsel B, Meydan D. Neuroendocrine carcinoma of the rectum. J. Exp. Clin. Med. 2019;34:275–278.
MLA Serarslan, Alparslan vd. “Neuroendocrine Carcinoma of the Rectum”. Journal of Experimental and Clinical Medicine, c. 34, sy. 4, 2019, ss. 275-8.
Vancouver Serarslan A, Ozbek Okumus N, Karagoz F, Nural MS, Gürsel B, Meydan D. Neuroendocrine carcinoma of the rectum. J. Exp. Clin. Med. 2019;34(4):275-8.