Sinonasal neoplasms: A tertiar center experience

Year 2021, Volume: 38 Issue: 1, 16 - 20, 26.01.2021

Dursun Mehmet Mehel , Abdulkadir Özgür , Samet Aydemir , Mehmet Çelebi , Doğukan Özdemir , Gökhan Akgül , Semih Van

Abstract

Primary tumors of the nasal cavity can be classified as benign or malignant. Patients with tumors of the nose and paranasal sinuses are usually diagnosed in the advanced stages of the disease. The aim of this study was to evaluate the data of patients who were operated for sinonasal masses in our clinic in light of the literature. Between January 2016 and December 2018, 357 cases of sinonasal masses presenting to the Otorhinolaryngology Department of the Health Science University at the Samsun Training and Research Hospital were retrospectively screened and included in the study. Of the 357 patients included in the study, 256 (72%) were male, and 101 (28%) were female. The most common symptom was nasal obstruction (90%). Most of the benign cases were nasal polyps (90.2%), while the next most frequent diagnosis was inverted papilloma (4.7%). Malign neoplasms were found in 11 cases, and five were found to be squamous cell carcinomas (SCC). All benign cases were treated surgically, and the malignant cases were treated according to the diagnosis. In conclusion, although the symptoms of the 357 patients with sinonasal mass were similar, histopathological evaluation revealed 96.9% benign and 3.1% malign pathologies. The malign/benign ratio was 3.08. Malignancy should therefore be considered as a possibility in patients with nasal bleeding and facial swelling.

Keywords

Sinonasal neoplasms, , symptom

References

• Brinton LA, Blot WJ, Becker JA. A case-Control Study of Cancers of the Nasal Cavity and Paranasal Sinuses. Am J Epidemiol 1994; 6: 896 - 906.
• Constantino Gde T, Abdo TT, Romano FR, Voegels RL, Butugan O. The role of endoscopic surgery in the treatment of nasal inverted papilloma. Braz J Otorhinolaryngol. 2007; 73(1): 65-68.
• Frierson HF. Pathologic quiz, case I. Arch Otolaryngol Head Neck Surg. 1986; 112: 568-570.
• Kitapçı F, Muluk NB, Atasoy P, Koç C. Nazal polpler. Van Tıp Dergisi 2005;12(3): 212-222.
• Lee CH, Hur DG, Roh HJ, Rha KS, Jin HR, Rhee CS, Min YG. Survival rotes of sinonasal squamous cell carcinoma with the new AJCC staging system. Arch Otolaryngol Head Neck Surg. 2007; 133(2): 131-134.
• Lund V: Malignant Tumors of the Nasal Cavity and paranasal Sinuses. ORL.45:1-12,1983.
• Maniglia AJ and David PA. Midfacial degloving for the manegement of nasalsinus and skull-base neoplam –Paranasal sinus Tumors. Otolaryngologic Clinics of Nort America. 1995; 28(6):1127.
• Thompson LDR, Franchi A. New tumor entities in the 4th edition of the World Health Organization classification of head and neck tumors: Nasal cavity, paranasal sinuses and skull base. Virchows Archiv. 2017; 472(3): 315–330.
• Tritt S, Mc Mains KC, Kountakis SE. Unilateral nasal polyposis: clinical presentation and pathology. Am J Otolaryngol 2008; 29(4): 230-232.
• Zhao RW, Guo ZQ, Zhang RX. Human papillomavirus infection and the malinant transformation of sinonasal inverted papilloma: A meta-analysis. Journal of Clinical Virology. 2016; 79: 36-43.