Research Article
BibTex RIS Cite

Nailfold capillaroscopy findings for patients receiving hemodialysis treatment and patients with renal transplant

Year 2022, Volume: 39 Issue: 1, 28 - 31, 01.01.2022

Abstract

Cardiovascular diseases are the most common cause of death in hemodialysis patients. Early diagnosis of cardiovascular diseases has vital importance. The aim of our study is to use the NFC method to determine the importance of microcirculatory structure changes for early detection of increased cardiovascular disease risk in hemodialysis patients. The research was performed from april/2017 to july/2017. The study included 15 patients receiving hemodialysis treatment and 15 renal transplant patients followed by the nephrology department and 15 healthy volunteers attending the internal diseases clinic. Every patient were examined by videocapillaroscopy according to procedure and data were recorded. Statistical analyses were evaluated with SPSS 22.0. There was a significant difference in laboratory values between hemodialysis patients and both groups except uric acid (p<0.05). There was not a significant difference between the groups in terms of capillary density, capillary hemorrhage rate, tortuous capillary incidence, and giant capillary incidence (p>0.05). In conclusion, investigation of nailfold capillaroscopy in hemodialysis and renal transplant patients did not identify a significant disruption in microcirculation compared to the healthy control group. There is a need for nailfold capillaroscopy studies of hemodialysis and renal transplant patients with higher numbers of patients.

Supporting Institution

Ankara Numune Education and Research Hospital Clinical Research Ethics Committee.

Project Number

04/2017

References

  • 1. Charles A Herzog, J Michael Mangrum, Rod Passman. Sudden cardiac death and dialysis patients. Semin Dial. Jul-Aug 2008;21(4):300-7.
  • 2. Secomb TW, Pries AR. The microcirculation: physiology at the mesoscale. J Physiol. 2011; 589:1047–1052.
  • 3. Khan, Faisel; Dean Patterson; Belch, Jill J.F.; Hirata, Kumiko; Lang, Chim C., Relationship between peripheral and coronary function using laser Doppler imaging and transthoracic echocardiography. 2008.
  • 4. IJzerman RG, De Jongh RT, MA Beijk, et al., Individuals at increased coronary heart disease risk are characterized by an impaired microvascular function in skin. Eur J Clin Invest 2003; 33:536-542.
  • 5. Chade AR. Renal vascular structure and rarefaction. Compr Physiol. 2013; 3:817–831.
  • 6. Antonios TF, Kaski JC, Hasan KM, et al. Rarefaction of skin capillaries in patients with anginal chest pain and normal coronary arteriograms. Eur Heart J. 2001; 22:1144–1148.
  • 7. Holowatz LA, Thompson-Torgerson CS, Kenney WL. The human cutaneous circulation as a model of generalized microvascular function. J Appl Physiol (1985) 2008; 105:370–372.
  • 8. Mahnaz Etehad Tavakol, Alimohammad Fatemi, and Björn-Erik Erlandsson,Nailfold Capillaroscopy in Rheumatic Diseases: Which Parameters Should Be Evaluated?Hindawi Publishing CorporationBioMed Research InternationalVolume 2015, Article ID 974530.
  • 9. Yüksel S, Yüksel EP, Soylu K, Zengin H, Gülel O, Meriç M, Aydın F, Şentürk N, Şahin M. Abnormal nail fold capillarospoic findings in patients with coronary slow phenomenon. Int J Clin Exp Med. 2014;7(4):1052-1058.
  • 10. Mario Cozzolino, Michela Mangano, Andrea Stucchi, Paola Ciceri, Ferruccio Conte, Andrea Galassi. Cardiovascular disease in dialysis patients Nephrol Dial Transplant. 2018 Oct; 33(Suppl 3): iii28–iii34. Published online 2018 Oct 3.
  • 11. Eduardo Tibiriçá, Andrea De Lorenzo, Gláucia Maria Moraes de Oliveira. Microcirculation and Cardiovascular Diseases Arq Bras Cardiol. 2018 Aug; 111(2): 120–121.
  • 12. Thang OH, Serné EH, Grooteman MP, Smulders YM, ter Wee PM, Tangelder GJ, Nubé MJ. Capillary rarefaction in advanced chronic kidney disease is associated with high phosphorus and bicarbonate levels. Nephrol Dial Transplant. 2011 Nov;26(11):3529-36.
  • 13. Hirschl M, Kundi M, Hirschl MM. Microcirculation of nailfold capillaries in chronic hemodialysis patients with and without diabetes mellitus. Clin Nephrol. 1993 Sep;40(3):179-84.
  • 14. Edwards-Richards A, DeFreitas M, Katsoufis CP, et al. Capillary rarefaction: an early marker of microvascular disease in young hemodialysis patients. Clin Kidney J. 2014;7(6):569-574.
  • 15. Akkiraz, Zehra Ozde. Establishment of peripheral vascular alteration with videocapilleroscopy method in migraine patients. Master’s thesis. İzmir Katip Çelebi University, 2016.
  • 16. Erol MK, Balkarli A, Toslak D, Dogan B, Durmaz D, Süren E, et al. Evaluation of nailfold videocapillaroscopy in central serous chorioretinopathy. Graefes Arch Clin Exp Ophthalmol. 2016 Oct;254(10):1889-1896.
Year 2022, Volume: 39 Issue: 1, 28 - 31, 01.01.2022

Abstract

Project Number

04/2017

References

  • 1. Charles A Herzog, J Michael Mangrum, Rod Passman. Sudden cardiac death and dialysis patients. Semin Dial. Jul-Aug 2008;21(4):300-7.
  • 2. Secomb TW, Pries AR. The microcirculation: physiology at the mesoscale. J Physiol. 2011; 589:1047–1052.
  • 3. Khan, Faisel; Dean Patterson; Belch, Jill J.F.; Hirata, Kumiko; Lang, Chim C., Relationship between peripheral and coronary function using laser Doppler imaging and transthoracic echocardiography. 2008.
  • 4. IJzerman RG, De Jongh RT, MA Beijk, et al., Individuals at increased coronary heart disease risk are characterized by an impaired microvascular function in skin. Eur J Clin Invest 2003; 33:536-542.
  • 5. Chade AR. Renal vascular structure and rarefaction. Compr Physiol. 2013; 3:817–831.
  • 6. Antonios TF, Kaski JC, Hasan KM, et al. Rarefaction of skin capillaries in patients with anginal chest pain and normal coronary arteriograms. Eur Heart J. 2001; 22:1144–1148.
  • 7. Holowatz LA, Thompson-Torgerson CS, Kenney WL. The human cutaneous circulation as a model of generalized microvascular function. J Appl Physiol (1985) 2008; 105:370–372.
  • 8. Mahnaz Etehad Tavakol, Alimohammad Fatemi, and Björn-Erik Erlandsson,Nailfold Capillaroscopy in Rheumatic Diseases: Which Parameters Should Be Evaluated?Hindawi Publishing CorporationBioMed Research InternationalVolume 2015, Article ID 974530.
  • 9. Yüksel S, Yüksel EP, Soylu K, Zengin H, Gülel O, Meriç M, Aydın F, Şentürk N, Şahin M. Abnormal nail fold capillarospoic findings in patients with coronary slow phenomenon. Int J Clin Exp Med. 2014;7(4):1052-1058.
  • 10. Mario Cozzolino, Michela Mangano, Andrea Stucchi, Paola Ciceri, Ferruccio Conte, Andrea Galassi. Cardiovascular disease in dialysis patients Nephrol Dial Transplant. 2018 Oct; 33(Suppl 3): iii28–iii34. Published online 2018 Oct 3.
  • 11. Eduardo Tibiriçá, Andrea De Lorenzo, Gláucia Maria Moraes de Oliveira. Microcirculation and Cardiovascular Diseases Arq Bras Cardiol. 2018 Aug; 111(2): 120–121.
  • 12. Thang OH, Serné EH, Grooteman MP, Smulders YM, ter Wee PM, Tangelder GJ, Nubé MJ. Capillary rarefaction in advanced chronic kidney disease is associated with high phosphorus and bicarbonate levels. Nephrol Dial Transplant. 2011 Nov;26(11):3529-36.
  • 13. Hirschl M, Kundi M, Hirschl MM. Microcirculation of nailfold capillaries in chronic hemodialysis patients with and without diabetes mellitus. Clin Nephrol. 1993 Sep;40(3):179-84.
  • 14. Edwards-Richards A, DeFreitas M, Katsoufis CP, et al. Capillary rarefaction: an early marker of microvascular disease in young hemodialysis patients. Clin Kidney J. 2014;7(6):569-574.
  • 15. Akkiraz, Zehra Ozde. Establishment of peripheral vascular alteration with videocapilleroscopy method in migraine patients. Master’s thesis. İzmir Katip Çelebi University, 2016.
  • 16. Erol MK, Balkarli A, Toslak D, Dogan B, Durmaz D, Süren E, et al. Evaluation of nailfold videocapillaroscopy in central serous chorioretinopathy. Graefes Arch Clin Exp Ophthalmol. 2016 Oct;254(10):1889-1896.
There are 16 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Clinical Research
Authors

Harun Küçük 0000-0003-3957-1778

Azar Abiyev 0000-0002-9840-7348

Şeminur Haznedaroğlu This is me 0000-0003-3929-6884

Project Number 04/2017
Early Pub Date January 3, 2022
Publication Date January 1, 2022
Submission Date April 27, 2021
Acceptance Date June 12, 2021
Published in Issue Year 2022 Volume: 39 Issue: 1

Cite

APA Küçük, H., Abiyev, A., & Haznedaroğlu, Ş. (2022). Nailfold capillaroscopy findings for patients receiving hemodialysis treatment and patients with renal transplant. Journal of Experimental and Clinical Medicine, 39(1), 28-31.
AMA Küçük H, Abiyev A, Haznedaroğlu Ş. Nailfold capillaroscopy findings for patients receiving hemodialysis treatment and patients with renal transplant. J. Exp. Clin. Med. January 2022;39(1):28-31.
Chicago Küçük, Harun, Azar Abiyev, and Şeminur Haznedaroğlu. “Nailfold Capillaroscopy Findings for Patients Receiving Hemodialysis Treatment and Patients With Renal Transplant”. Journal of Experimental and Clinical Medicine 39, no. 1 (January 2022): 28-31.
EndNote Küçük H, Abiyev A, Haznedaroğlu Ş (January 1, 2022) Nailfold capillaroscopy findings for patients receiving hemodialysis treatment and patients with renal transplant. Journal of Experimental and Clinical Medicine 39 1 28–31.
IEEE H. Küçük, A. Abiyev, and Ş. Haznedaroğlu, “Nailfold capillaroscopy findings for patients receiving hemodialysis treatment and patients with renal transplant”, J. Exp. Clin. Med., vol. 39, no. 1, pp. 28–31, 2022.
ISNAD Küçük, Harun et al. “Nailfold Capillaroscopy Findings for Patients Receiving Hemodialysis Treatment and Patients With Renal Transplant”. Journal of Experimental and Clinical Medicine 39/1 (January 2022), 28-31.
JAMA Küçük H, Abiyev A, Haznedaroğlu Ş. Nailfold capillaroscopy findings for patients receiving hemodialysis treatment and patients with renal transplant. J. Exp. Clin. Med. 2022;39:28–31.
MLA Küçük, Harun et al. “Nailfold Capillaroscopy Findings for Patients Receiving Hemodialysis Treatment and Patients With Renal Transplant”. Journal of Experimental and Clinical Medicine, vol. 39, no. 1, 2022, pp. 28-31.
Vancouver Küçük H, Abiyev A, Haznedaroğlu Ş. Nailfold capillaroscopy findings for patients receiving hemodialysis treatment and patients with renal transplant. J. Exp. Clin. Med. 2022;39(1):28-31.