Multidrug resistant microorganisms in the ıntensive care unit without COVID-19 during pandemic

Yıl 2022, Cilt: 39 Sayı: 1, 210 - 215, 01.01.2022

Özgür Kömürcü Mehmet Gökhan Taflan İlkay Bozkurt Yeliz Tanrıverdi Çaycı Fatma Ulger

Öz

There are very few reports on the prevalence of multidrug-resistant microorganisms during the COVID-19 pandemic. In addition, these publications usually cover covid-19 patients.Our study aimed to compare the prevalence of multidrug-resistant microorganisms in patients without COVID-19 undergoing treatment in an intensive care unit (ICU) during the COVID-19 pandemic with those in the pre-pandemic period. The study was planned retrospectively. In our country, the prevalence of multi-drug-resistant microorganisms was evaluated in the intensive care unit where internal and surgical patients were hospitalized in a single center in 6-month periods before and after the occurrence of covid-19 cases. The prevalence of multidrug-resistant microorganisms increased in patients being followed up in our ICU during the pandemic period (p<0.05). Statistically significant relationships were found between the incidence rate of microorganisms with multi-drug resistance and sex (p=0.028), presence of malignancy (p=0.011), and nurse’s duration of work in the ICU (p=0.04). The increased prevalence of multidrug-resistant microorganisms and the infections caused by these microorganisms are other challenges that must be tackled during the pandemic period.

Anahtar Kelimeler

Coronavirus pandemic, Multidrug resistansresistant microorganisms, Intensive care unit, COVID-19

Proje Numarası

KA2020/618

Kaynakça

• 1. Morens DM, Daszak P, Taubenberger JK. Escaping Pandora's Box - Another Novel Coronavirus. N Engl J Med. 2020;382(14):1293-5. doi: 10.1056/NEJMp2002106. PubMed PMID: 32101660.
• 2. WHO. Coronavirus Disease (COVID-19) Dashboard. Data last updated: 2021/6/03.
• 3. Song Y, Zhang M, Yin L, Wang K, Zhou Y, Zhou M, et al. COVID-19 treatment: close to a cure? A rapid review of pharmacotherapies for the novel coronavirus (SARS-CoV-2). International Journal of Antimicrobial Agents. 2020;56(2):106080. doi: https://doi.org/10.1016/j.ijantimicag.2020.106080.
• 4. Alzyood M, Jackson D, Aveyard H, Brooke J. COVID-19 reinforces the importance of handwashing. J Clin Nurs. 2020;29(15-16):2760-1. Epub 2020/05/15. doi: 10.1111/jocn.15313. PubMed PMID: 32406958; PubMed Central PMCID: PMCPMC7267118.
• 5. Ruuskanen O, Lahti E, Jennings LC, Murdoch DR. Viral pneumonia. Lancet. 2011;377(9773):1264-75. doi: 10.1016/S0140-6736(10)61459-6. PubMed PMID: 21435708; PubMed Central PMCID: PMCPMC7138033.
• 6. Organization WH. Clinical management of severe acute respiratory infection (SARI) when COVID-19 disease is suspected: interim guidance, 13 March 2020. World Health Organization, 2020.
• 7. Langford BJ, So M, Raybardhan S, Leung V, Westwood D, MacFadden DR, et al. Bacterial co-infection and secondary infection in patients with COVID-19: a living rapid review and meta-analysis. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 2020;26(12):1622-9. Epub 07/22. doi: 10.1016/j.cmi.2020.07.016. PubMed PMID: 32711058.
• 8. WHO. Clinical management of COVID-19. WHO-2019-nCoV-clinical-20205-eng.
• 9. saglik.gov.tr. covid-19 rehberi eriskin hasta tedavisi. covid19saglikgovtr/Eklenti/39061/0/. 2020.
• 10. Cai H, Tu B, Ma J, Chen L, Fu L, Jiang Y, et al. Psychological Impact and Coping Strategies of Frontline Medical Staff in Hunan Between January and March 2020 During the Outbreak of Coronavirus Disease 2019 (COVID19) in Hubei, China. Med Sci Monit. 2020;26:e924171. doi: 10.12659/MSM.924171. PubMed PMID: 32291383; PubMed Central PMCID: PMCPMC7177038.
• 11. Jolivet S, Lolom I, Bailly S, Bouadma L, Lortat-Jacob B, Montravers P, et al. Impact of colonization pressure on acquisition of extended-spectrum β-lactamase-producing Enterobacterales and meticillin-resistant Staphylococcus aureus in two intensive care units: a 19-year retrospective surveillance. J Hosp Infect. 2020;105(1):10-6. Epub 2020/02/25. doi: 10.1016/j.jhin.2020.02.012. PubMed PMID: 32092367.
• 12. Ang H, Sun X. Risk factors for multidrug-resistant Gram-negative bacteria infection in intensive care units: A meta-analysis. International Journal of Nursing Practice. 2018;24(4):e12644. doi: https://doi.org/10.1111/ijn.12644.
• 13. Kaye KS, Patel DA, Stephens JM, Khachatryan A, Patel A, Johnson K. Rising United States Hospital Admissions for Acute Bacterial Skin and Skin Structure Infections: Recent Trends and Economic Impact. PLoS One. 2015;10(11):e0143276. doi: 10.1371/journal.pone.0143276. PubMed PMID: 26599005; PubMed Central PMCID: PMCPMC4657980.
• 14. Chelazzi C, Pettini E, Villa G, De Gaudio AR. Epidemiology, associated factors and outcomes of ICU-acquired infections caused by Gram-negative bacteria in critically ill patients: an observational, retrospective study. BMC Anesthesiol. 2015;15:125. doi: 10.1186/s12871-015-0106-9. PubMed PMID: 26392077; PubMed Central PMCID: PMCPMC4578757.
• 15. Liu Q, Li W, Du X, Li W, Zhong T, Tang Y, et al. Risk and Prognostic Factors for Multidrug-Resistant Acinetobacter Baumannii Complex Bacteremia: A Retrospective Study in a Tertiary Hospital of West China. PLOS ONE. 2015;10(6):e0130701. doi: 10.1371/journal.pone.0130701.
• 16. Tenney J, Hudson N, Alnifaidy H, Li JTC, Fung KH. Risk factors for aquiring multidrug-resistant organisms in urinary tract infections: A systematic literature review. Saudi Pharmaceutical Journal. 2018;26(5):678-84. doi: https://doi.org/10.1016/j.jsps.2018.02.023.
• 17. Hogan BV, Peter MB, Shenoy HG, Horgan K, Hughes TA. Surgery induced immunosuppression. The Surgeon. 2011;9(1):38-43. doi: https://doi.org/10.1016/j.surge.2010.07.011.
• 18. Patolia S, Abate G, Patel N, Patolia S, Frey S. Risk factors and outcomes for multidrug-resistant Gram-negative bacilli bacteremia. Therapeutic advances in infectious disease. 2018;5(1):11-8. Epub 09/12. doi: 10.1177/2049936117727497. PubMed PMID: 29344356.
• 19. Timsit JF, Schwebel C, Bouadma L, Geffroy A, Garrouste-Orgeas M, Pease S, et al. Chlorhexidine-impregnated sponges and less frequent dressing changes for prevention of catheter-related infections in critically ill adults: a randomized controlled trial. Jama. 2009;301(12):1231-41. Epub 2009/03/26. doi: 10.1001/jama.2009.376. PubMed PMID: 19318651.
• 20. Jung JY, Park MS, Kim SE, Park BH, Son JY, Kim EY, et al. Risk factors for multi-drug resistant Acinetobacter baumanniibacteremia in patients with colonization in the intensive care unit. BMC Infectious Diseases. 2010;10(1):228. doi: 10.1186/1471-2334-10-228.
• 21. Lebeaux D, Fernández-Hidalgo N, Chauhan A, Lee S, Ghigo JM, Almirante B, et al. Management of infections related to totally implantable venous-access ports: challenges and perspectives. Lancet Infect Dis. 2014;14(2):146-59. Epub 2013/12/10. doi: 10.1016/s1473-3099(13)70266-4. PubMed PMID: 24314751.
• 22. Osti C, Wosti D, Pandey B, Zhao Q. Ventilator-Associated Pneumonia and Role of Nurses in Its Prevention. Journal of the Nepal Medical Association. 2017;56(208).