Maternal and perinatal outcomes of SARS-COV-2 Infection in Vaccinated Compared with Unvaccinated Pregnant Patients

Year 2023, Volume: 40 Issue: 2, 312 - 317, 19.07.2023

Sevtap Seyfettinoğlu , Cevdet Adıgüzel , Sevda Baş , Sefa Arlıer , Şevki Göksun Gökulu , Mehmet Narin , Raziye Narin

Abstract

The objective of this study is to evaluate maternal and fetal outcomes of Covid-19 in vaccinated compared with unvaccinated pregnant patients. The study included 244 pregnant patients with COVID-19 infection confirmed by a positive SARS-CoV-2 polymerized chain reaction (PCR) test. Two hundred-four patients were not unvaccinated, and 40 patients were vaccinated. The clinical, biochemical, radiological results and maternofetal outcomes of the pregnant patients were recorded. All the data were evaluated statistically. The pregnant patients included in the study had a mean age of 31.4 in the vaccinated group, and 28.3 years in the unvaccinated group. Comorbidities were determined in 25% of the patients, and the most common symptom was fever in 65.5% of cases. Sore throat, loss of taste sensation, and loss of smell sensation were detected significantly more in the unvaccinated group (p<0.01). Most of the patients were in third-trimester pregnancy in both groups. No patient in the vaccinated group needed intensive care due to covid. A significant difference was found between the two groups in terms of neonatal intensive care requirements.
This study determined that intensive care requirement is increased for both mother and newborn, covid symptoms could be prolonged and hospital stay is longer in the unvaccinated group. Considering these data, the covid-19 vaccine should be offered to all pregnant women.

Keywords

COVID-19, vaccine, pregnancy, cesarean, intensive care

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