Obstructive sleep apnea (OSA) is highly prevalent in individuals with Down syndrome (DS), affecting more than 50% of this population during childhood and reaching up to 100% in adulthood. This disorder poses significant clinical consequences, including impaired cognitive function, developmental delay, and cardiovascular complications. To address this, direct hypoglossal nerve stimulation (HNS) has been approved as a treatment modality for OSA. Recent studies have shown a significant positive correlation between HNS voltage and post-apnea-hypopnea index (AHI) levels in DS and non-DS patients. However, concerns regarding the reliability of some findings have been raised, emphasizing the need for further research to underline the usefulness of HNS in treating OSA in DS patients. This meta-analysis provides a comprehensive review and analysis of the available case reports, case series, and cohort studies to evaluate the safety and efficacy of HNS in treating OSA in Down syndrome patients.
Birincil Dil | İngilizce |
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Konular | Beyin ve Sinir Cerrahisi (Nöroşirurji) |
Bölüm | Review Articles |
Yazarlar | |
Yayımlanma Tarihi | 19 Mayıs 2024 |
Gönderilme Tarihi | 17 Şubat 2024 |
Kabul Tarihi | 18 Nisan 2024 |
Yayımlandığı Sayı | Yıl 2024 Cilt: 41 Sayı: 2 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.