Araştırma Makalesi
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Acil serviste KOAH atağı başvuruları ile hava kirliliği arasındaki ilişki

Yıl 2024, Cilt: 17 Sayı: 1, 17 - 25, 01.01.2024
https://doi.org/10.31362/patd.1320033

Öz

Amaç: Çalışmamızda hava kirliliği, sıcaklık ve KOAH atakları arasındaki ilişkiyi iki farklı merkezde araştırmayı amaçladık.
Gereç ve yöntem: Bandırma ve Van olmak üzere iki merkez çalışmaya dâhil edildi. Ayrıca sıcaklık gruplandırması da yapılmıştır. Hava kirliliği ve sıcaklık değerleri resmi sitelerden alınmıştır. KOAH verileri geriye dönük olarak hastane bilgi yönetim sistemlerinden tarandı.
Bulgular: Çalışmaya alınan ilk 3 aylık dönemde (Grup 1) de Van’ daki hava kirliliği ölçütü olan PM10 değeri Bandırma’ya göre daha yüksek saptanmıştır (p=0,05). Benzer şekilde acil serviste COPD tedavisi ve acil servisten COPD yatış sayıları da Van’da yüksek saptanmıştır (sırasıyla p=0,05 ve p=0,034). Çalışmaya alınan son 3 aylık periyodda sıcaklık ortalamasının Van’ da daha düşük ve acil servisten COPD nedenli yatışların ve yatış oranının daha fazla olduğu gözlenmiştir (sırasıyla p=0,05, p=0,05 ve p=0,05). Yapılan korelasyon analizinde Grup 1’ de PM10 değeri arttıkça acil serviste COPD tedavisi alma ve COPD nedenli yatışta kuvvetli bir pozitif korelasyon saptanmıştır (sırasıyla r;0,986, p<0,001 ve r;0,885, p=0,019). Grup 2’ de hava sıcaklıklarının düşmesi ile acil serviste COPD tedavisi alma, COPD nedenli yatışta ve yatış oranlarında kuvvetli bir negatif korelasyon saptanmıştır (sırasıyla r;-0,905, p=0,013, r;-0,966, p=0,002 ve r;-0,867, p=0,025).
Sonuç: KOAH atakları sıcaklık ve hava kirliliği ile ilişkilidir. Acil servislerde KOAH atakları için sıcaklık yanı sıra hava kirliliği parametreleri yakından takip edilerek yoğunluktaki olası artışlar tahmin edilebilir.

Destekleyen Kurum

yok

Teşekkür

Yok

Kaynakça

  • 1. Ko FWS, Hui DSC. Air pollution and chronic obstructive pulmonary disease. Respirology 2012;17:395-401. https://doi.org/10.1111/j.1440-1843.2011.02112.x
  • 2. Burge AT, Cox NS, Abramson MJ, Holland AE. Interventions for promoting physical activity in people with chronic obstructive pulmonary disease (COPD). Cochrane Database Syst Rev 2020;4:CD012626. https://doi.org/10.1002/14651858.CD012626.pub2 3. Gonlugur U, Gonlugur T. Seasonal variations in exacerbations of chronic obstructive pulmonary disease. Kocaeli Medical J 2020:140-146. https://doi.org/10.5505/ktd.2020.78055
  • 4. Park J, Kim HJ, Lee CH, Lee CH, Lee HW. Impact of long-term exposure to ambient air pollution on the incidence of chronic obstructive pulmonary disease: a systematic review and meta-analysis. Environ Res 2021;194:110703. https://doi.org/10.1016/j.envres.2020.110703
  • 5. Schikowski T, Adam M, Marcon A, et al. Association of ambient air pollution with the prevalence and incidence of COPD. Eur Respir J 2014;44:614-626. https://doi.org/10.1183/09031936.00132213
  • 6. Shin S, Bai L, Burnett RT, et al. Air pollution as a risk factor for ıncident chronic obstructive pulmonary disease and asthma. A 15-year population-based cohort study. Am J Respir Crit Care Med 2021;203:1138-1148. https://doi.org/10.1164/rccm.201909-1744OC
  • 7. Andersen ZJ, Hvidberg M, Jensen SS, et al. Chronic obstructive pulmonary disease and long-term exposure to traffic-related air pollution: a cohort study. Am J Respir Crit Care Med 2011;183:455-461. https://doi.org/10.1164/rccm.201006-0937OC
  • 8. Chen L, Cai M, Li H, et al. Risk/benefit tradeoff of habitual physical activity and air pollution on chronic pulmonary obstructive disease: findings from a large prospective cohort study. BMC Med 2022;20:70. https://doi.org/10.1186/s12916-022-02274-8
  • 9. Wise RA, Calverley PM, Carter K, Clerisme Beaty E, Metzdorf N, Anzueto A. Seasonal variations in exacerbations and deaths in patients with COPD during the TIOSPIR® trial. Int J Chron Obstruct Pulmon Dis 2018;13:605-616. https://doi.org/10.2147/COPD.S148393
  • 10. The air quality monitoring system of the T.C. Ministry of Environment, Urbanization and Climate. Available at: http://www.havaizleme.gov.tr. Accessed February 24, 2023
  • 11. The General Directorate of Meteorology. Available at: https://www.mgm.gov.tr. Accessed February 24, 2023
  • 12. Weather Spark. Available at: https://tr.weatherspark.com. Accessed February 24, 2023
  • 13. Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med 2006;3:442. https://doi.org/10.1371/journal.pmed.0030442
  • 14. Shehu E, Farruku H, Smaili H. Air pollution and socio-economic determinants of chronic obstructive pulmonary disease in albania. Curr Health Sci J 2022;48:51-56. https://doi.org/10.12865/CHSJ.48.01.07
  • 15. Erdem E. Kronik obstrüktif akciğer hastalığı akut atak etkenleri ve solunum fonksiyon parametreleri ile ilişkisi. Yayınlanmamış Yüksek Lisans Tezi. Fırat Üniversitesi Tıp Fakültesi Göğüs Hastalıkları Anabilim Dalı, Elazığ, 2011.
  • 16. Anderson HR, Spix C, Medina S, et al. Air pollution and daily admissions for chronic obstructive pulmonary disease in 6 European cities: results from the APHEA project. Eur Respir J 1997;10:1064-1071. https://doi.org/10.1183/09031936.97.10051064
  • 17. Glencross DA, Ho TR, Camiña N, Hawrylowicz CM, Pfeffer PE. Air pollution and its effects on the immune system. Free Radic Biol Med 2020;151:56-68. https://doi.org/10.1016/j.freeradbiomed.2020.01.179
  • 18. Bayram H, Dörtbudak Z, Evyapan Fişekçi F, Kargın M, Bülbül B. Hava kirliliğinin insan sağlığına etkileri, dünyada, ülkemizde ve bölgemizde hava kirliliği sorunu” paneli ardından. Dicle Tıp Dergisi 2006;33;105-112.
  • 19. Okan J. İktisadi kalkınma, hava kirliliği ve sağlık ilişkisi: panel veri analizi. Yayınlanmamış Yüksek Lisans Tezi. Yıldız Teknik Üniversitesi Sosyal Bilimler Enstitüsü İktisat Ana Bilim Dalı İktisat Yüksek Lisans Programı, İstanbul, 2017.
  • 20. Wang L, Xie J, Hu Y, Tian Y. Air pollution and risk of chronic obstructed pulmonary disease: the modifying effect of genetic susceptibility and lifestyle. EBioMedicine 2022;79:103994. https://doi.org/10.1016/j.ebiom.2022.103994
  • 21. Khilnani GC, Tiwari P. Air pollution in India and related adverse respiratory health effects: past, present, and future directions. Curr Opin Pulm Med 2018;24:108-116. https://doi.org/10.1097/MCP.0000000000000463
  • 22. Özüer MZ, Günhan Ö, Cura O. Değişik klimatolojik ve hava kirliliği değerlerinin nazal rezistansa etkisi. KBB ve Baş Boyun Cerrahisi Dergisi 1999:7:91-95.
  • 23. Ünsal A, Metintaş M, Öner S, İnan OÇ. Eskişehir’de hava kirliliği ve bazı hastalıklar nedeniyle acil başvuruların incelenmesi. Tüberküloz ve Toraks Dergisi 1999;47:449-455.
  • 24. Fişekçi F, Özkurt S, Başer S, Daloğlu G, Hacıoğlu M. Effect of air pollution on copd exacerbations. Eur Respir J 1999;14:393.
  • 25. Jenkins CR, Celli B, Anderson JA, et al. Seasonality and determinants of moderate and severe COPD exacerbations in the TORCH study. Eur Respir J 2012;39:38-45. https://doi.org/10.1183/09031936.00194610
  • 26. Hansel NN, McCormack MC, Kim V. The effects of air pollution and temperature on COPD. COPD 2016;13:372-379. https://doi.org/10.3109/15412555.2015.1089846
  • 27. Tseng CM, Chen YT, Ou SM, et al. The effect of cold temperature on increased exacerbation of chronic obstructive pulmonary disease: a nationwide study. PLoS One 2013;8:e57066. https://doi.org/10.1371/journal.pone.0057066
  • 28. Koskela HO, Koskela AK, Tukiaineu HO. Bronchoconstriction due to cold weather in COPD. The roles of direct airway effects and cutaneous reflex mechanisms. Chest 1996;110:632-636. https://doi.org/10.1378/chest.110.3.632
  • 29. Li M, Li Q, Yang G, Kolosov VP, Perelman JM, Zhou XD. Cold temperature induces mucin hypersecretion from normal human bronchial epithelial cells in vitro through a transient receptor potential melastatin 8 (TRPM8)-mediated mechanism. J Allergy Clin Immunol 2011;128:626-634. https://doi.org/10.1016/j.jaci.2011.04.032

The relationship between COPD attack applications and air pollution in the emergency department

Yıl 2024, Cilt: 17 Sayı: 1, 17 - 25, 01.01.2024
https://doi.org/10.31362/patd.1320033

Öz

Purpose: We aimed to investigate the relationship between air pollution, temperature and COPD attacks in two different centers.
Materials and methods: Two centers, Bandırma and Van, were included in the study. In addition, temperature grouping was also done. Air pollution and temperature values were obtained from official sites. COPD data were scanned retrospectively from hospital information management systems.
Results: In the first 3 months (Group 1) included in the study, the PM10 value, the number of COPD treatment in the emergency department (ED) and the number of COPD hospitalizations in the ED were also found to be high in Van (p=0.05, p=0.05 and p=0.034, respectively). In the last 3 months (Group 2) period included in the study, it
was observed that the mean temperature was lower in Van, and the rate of hospitalizations and hospitalizations due to COPD were higher in Van (p=0.05, p=0.05, and p=0.05, respectively). In the correlation analysis, a strong positive correlation was found between PM10 value and COPD treatment and hospitalization for COPD
in Group 1 (r;0.986, p<0.001 and r;0.885, p=0.019, respectively). In Group 2, a strong negative correlation was found between the decrease in air temperatures and COPD treatment in the ED, hospitalization due to COPD and hospitalization rates (r;-0.905, p=0.013, r;-0.966, p=0.002 ve r;-0.867, p=0.025, respectively).
Conclusion: COPD attacks are associated with temperature and air pollution. For COPD attacks in ED, possible increases in intensity can be estimated by closely monitoring air pollution parameters as well as temperature.

Kaynakça

  • 1. Ko FWS, Hui DSC. Air pollution and chronic obstructive pulmonary disease. Respirology 2012;17:395-401. https://doi.org/10.1111/j.1440-1843.2011.02112.x
  • 2. Burge AT, Cox NS, Abramson MJ, Holland AE. Interventions for promoting physical activity in people with chronic obstructive pulmonary disease (COPD). Cochrane Database Syst Rev 2020;4:CD012626. https://doi.org/10.1002/14651858.CD012626.pub2 3. Gonlugur U, Gonlugur T. Seasonal variations in exacerbations of chronic obstructive pulmonary disease. Kocaeli Medical J 2020:140-146. https://doi.org/10.5505/ktd.2020.78055
  • 4. Park J, Kim HJ, Lee CH, Lee CH, Lee HW. Impact of long-term exposure to ambient air pollution on the incidence of chronic obstructive pulmonary disease: a systematic review and meta-analysis. Environ Res 2021;194:110703. https://doi.org/10.1016/j.envres.2020.110703
  • 5. Schikowski T, Adam M, Marcon A, et al. Association of ambient air pollution with the prevalence and incidence of COPD. Eur Respir J 2014;44:614-626. https://doi.org/10.1183/09031936.00132213
  • 6. Shin S, Bai L, Burnett RT, et al. Air pollution as a risk factor for ıncident chronic obstructive pulmonary disease and asthma. A 15-year population-based cohort study. Am J Respir Crit Care Med 2021;203:1138-1148. https://doi.org/10.1164/rccm.201909-1744OC
  • 7. Andersen ZJ, Hvidberg M, Jensen SS, et al. Chronic obstructive pulmonary disease and long-term exposure to traffic-related air pollution: a cohort study. Am J Respir Crit Care Med 2011;183:455-461. https://doi.org/10.1164/rccm.201006-0937OC
  • 8. Chen L, Cai M, Li H, et al. Risk/benefit tradeoff of habitual physical activity and air pollution on chronic pulmonary obstructive disease: findings from a large prospective cohort study. BMC Med 2022;20:70. https://doi.org/10.1186/s12916-022-02274-8
  • 9. Wise RA, Calverley PM, Carter K, Clerisme Beaty E, Metzdorf N, Anzueto A. Seasonal variations in exacerbations and deaths in patients with COPD during the TIOSPIR® trial. Int J Chron Obstruct Pulmon Dis 2018;13:605-616. https://doi.org/10.2147/COPD.S148393
  • 10. The air quality monitoring system of the T.C. Ministry of Environment, Urbanization and Climate. Available at: http://www.havaizleme.gov.tr. Accessed February 24, 2023
  • 11. The General Directorate of Meteorology. Available at: https://www.mgm.gov.tr. Accessed February 24, 2023
  • 12. Weather Spark. Available at: https://tr.weatherspark.com. Accessed February 24, 2023
  • 13. Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med 2006;3:442. https://doi.org/10.1371/journal.pmed.0030442
  • 14. Shehu E, Farruku H, Smaili H. Air pollution and socio-economic determinants of chronic obstructive pulmonary disease in albania. Curr Health Sci J 2022;48:51-56. https://doi.org/10.12865/CHSJ.48.01.07
  • 15. Erdem E. Kronik obstrüktif akciğer hastalığı akut atak etkenleri ve solunum fonksiyon parametreleri ile ilişkisi. Yayınlanmamış Yüksek Lisans Tezi. Fırat Üniversitesi Tıp Fakültesi Göğüs Hastalıkları Anabilim Dalı, Elazığ, 2011.
  • 16. Anderson HR, Spix C, Medina S, et al. Air pollution and daily admissions for chronic obstructive pulmonary disease in 6 European cities: results from the APHEA project. Eur Respir J 1997;10:1064-1071. https://doi.org/10.1183/09031936.97.10051064
  • 17. Glencross DA, Ho TR, Camiña N, Hawrylowicz CM, Pfeffer PE. Air pollution and its effects on the immune system. Free Radic Biol Med 2020;151:56-68. https://doi.org/10.1016/j.freeradbiomed.2020.01.179
  • 18. Bayram H, Dörtbudak Z, Evyapan Fişekçi F, Kargın M, Bülbül B. Hava kirliliğinin insan sağlığına etkileri, dünyada, ülkemizde ve bölgemizde hava kirliliği sorunu” paneli ardından. Dicle Tıp Dergisi 2006;33;105-112.
  • 19. Okan J. İktisadi kalkınma, hava kirliliği ve sağlık ilişkisi: panel veri analizi. Yayınlanmamış Yüksek Lisans Tezi. Yıldız Teknik Üniversitesi Sosyal Bilimler Enstitüsü İktisat Ana Bilim Dalı İktisat Yüksek Lisans Programı, İstanbul, 2017.
  • 20. Wang L, Xie J, Hu Y, Tian Y. Air pollution and risk of chronic obstructed pulmonary disease: the modifying effect of genetic susceptibility and lifestyle. EBioMedicine 2022;79:103994. https://doi.org/10.1016/j.ebiom.2022.103994
  • 21. Khilnani GC, Tiwari P. Air pollution in India and related adverse respiratory health effects: past, present, and future directions. Curr Opin Pulm Med 2018;24:108-116. https://doi.org/10.1097/MCP.0000000000000463
  • 22. Özüer MZ, Günhan Ö, Cura O. Değişik klimatolojik ve hava kirliliği değerlerinin nazal rezistansa etkisi. KBB ve Baş Boyun Cerrahisi Dergisi 1999:7:91-95.
  • 23. Ünsal A, Metintaş M, Öner S, İnan OÇ. Eskişehir’de hava kirliliği ve bazı hastalıklar nedeniyle acil başvuruların incelenmesi. Tüberküloz ve Toraks Dergisi 1999;47:449-455.
  • 24. Fişekçi F, Özkurt S, Başer S, Daloğlu G, Hacıoğlu M. Effect of air pollution on copd exacerbations. Eur Respir J 1999;14:393.
  • 25. Jenkins CR, Celli B, Anderson JA, et al. Seasonality and determinants of moderate and severe COPD exacerbations in the TORCH study. Eur Respir J 2012;39:38-45. https://doi.org/10.1183/09031936.00194610
  • 26. Hansel NN, McCormack MC, Kim V. The effects of air pollution and temperature on COPD. COPD 2016;13:372-379. https://doi.org/10.3109/15412555.2015.1089846
  • 27. Tseng CM, Chen YT, Ou SM, et al. The effect of cold temperature on increased exacerbation of chronic obstructive pulmonary disease: a nationwide study. PLoS One 2013;8:e57066. https://doi.org/10.1371/journal.pone.0057066
  • 28. Koskela HO, Koskela AK, Tukiaineu HO. Bronchoconstriction due to cold weather in COPD. The roles of direct airway effects and cutaneous reflex mechanisms. Chest 1996;110:632-636. https://doi.org/10.1378/chest.110.3.632
  • 29. Li M, Li Q, Yang G, Kolosov VP, Perelman JM, Zhou XD. Cold temperature induces mucin hypersecretion from normal human bronchial epithelial cells in vitro through a transient receptor potential melastatin 8 (TRPM8)-mediated mechanism. J Allergy Clin Immunol 2011;128:626-634. https://doi.org/10.1016/j.jaci.2011.04.032

Ayrıntılar

Birincil Dil İngilizce
Konular Acil Tıp
Bölüm Araştırma Makalesi
Yazarlar

Hülya YILMAZ BAŞER 0000-0002-1416-1521

Hale Nur CAN 0000-0002-8107-3986

Proje Numarası yok
Erken Görünüm Tarihi 22 Ağustos 2023
Yayımlanma Tarihi 1 Ocak 2024
Gönderilme Tarihi 26 Haziran 2023
Kabul Tarihi 21 Ağustos 2023
Yayımlandığı Sayı Yıl 2024 Cilt: 17 Sayı: 1

Kaynak Göster

APA YILMAZ BAŞER, H., & CAN, H. N. (2024). The relationship between COPD attack applications and air pollution in the emergency department. Pamukkale Medical Journal, 17(1), 17-25. https://doi.org/10.31362/patd.1320033
AMA YILMAZ BAŞER H, CAN HN. The relationship between COPD attack applications and air pollution in the emergency department. Pam Tıp Derg. Ocak 2024;17(1):17-25. doi:10.31362/patd.1320033
Chicago YILMAZ BAŞER, Hülya, ve Hale Nur CAN. “The Relationship Between COPD Attack Applications and Air Pollution in the Emergency Department”. Pamukkale Medical Journal 17, sy. 1 (Ocak 2024): 17-25. https://doi.org/10.31362/patd.1320033.
EndNote YILMAZ BAŞER H, CAN HN (01 Ocak 2024) The relationship between COPD attack applications and air pollution in the emergency department. Pamukkale Medical Journal 17 1 17–25.
IEEE H. YILMAZ BAŞER ve H. N. CAN, “The relationship between COPD attack applications and air pollution in the emergency department”, Pam Tıp Derg, c. 17, sy. 1, ss. 17–25, 2024, doi: 10.31362/patd.1320033.
ISNAD YILMAZ BAŞER, Hülya - CAN, Hale Nur. “The Relationship Between COPD Attack Applications and Air Pollution in the Emergency Department”. Pamukkale Medical Journal 17/1 (Ocak 2024), 17-25. https://doi.org/10.31362/patd.1320033.
JAMA YILMAZ BAŞER H, CAN HN. The relationship between COPD attack applications and air pollution in the emergency department. Pam Tıp Derg. 2024;17:17–25.
MLA YILMAZ BAŞER, Hülya ve Hale Nur CAN. “The Relationship Between COPD Attack Applications and Air Pollution in the Emergency Department”. Pamukkale Medical Journal, c. 17, sy. 1, 2024, ss. 17-25, doi:10.31362/patd.1320033.
Vancouver YILMAZ BAŞER H, CAN HN. The relationship between COPD attack applications and air pollution in the emergency department. Pam Tıp Derg. 2024;17(1):17-25.
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