The Relationship Between Euthyroid, Hyperthyroid, Hypothyroid, and Type 2 Diabetes

Zerrin Kutlu; Afra Dilay Kamacı

doi:10.5152/Pharmata.2023.23009

The Relationship Between Euthyroid, Hyperthyroid, Hypothyroid, and Type 2 Diabetes

Öz

Diabetes mellitus (DM) and thyroid dysfunction, which have a significant incidence worldwide, are the most common endocrine system disorders that occur together in patients. Our aim is to explain these 2 diseases with high incidence and the relationship between these 2 diseases. Thyroid hormones (TH) are essential hormones that govern body metabolism. Thyroid hormone changes are thought to be effective on the pathogenesis of DM. Diabetes mellitus treatments can be beneficial, as TH changes may contribute to the pathogenesis of DM. However, more research needs to be done. This lack of information limits potential biomarkers and targets for diagnosis, prognosis, and the development of new DM treatments. The limitations of the use of natural THs have led to the development of synthetic hormones called thyromimetics. However, most of the thyromimetics tested so far have been ineffective or toxic.

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