Politeknik Dergisi 2147-9429 Gazi Üniversitesi 10.2339/politeknik.1263520 Engineering Mühendislik Otomatik Folikül Saptama Yöntemleri Kullanılarak ESA Tabanlı Polikistik Over Sendromu Tespiti CNN Based Determination of Polycystic Ovarian Syndrome using Automatic Follicle Detection Methods https://orcid.org/0000-0001-6749-332X Gülhan Perihan Gülşah AKSARAY UNIVERSITY https://orcid.org/0000-0003-3007-5807 Özmen Güzin SELÇUK ÜNİVERSİTESİ https://orcid.org/0000-0003-0851-9002 Alptekin Hüsnü Medicana Hospital 09 25 2024 27 4 1589 1601 03 10 2023 07 28 2023 Copyright © 1998, Politeknik Dergisi 1998 Politeknik Dergisi

Bu çalışmanın amacı, yumurtalık ultrason görüntülerini kullanarak folikül tespiti için en iyi yöntemi belirlemek ve önerilen CNN mimarisini kullanarak ultrason görüntülerini pkos veya normal yumurtalık olarak sınıflandırmaktır. Pkos'u değerlendirmek için folikül tespitinde iki farklı yöntem önerilmiştir. Bu amaçla Ortanca, Ortalama, Wiener ve Gauss filtresi; standart ve uyarlanabilir eşikle test edilmiştir. İkinci olarak, Gauss filtreleme, Ayrık Dalgacık Dönüşümü ve k-means kümeleme algoritması test edilmiştir. Segmentasyon aşamasında folikülleri arka plandan ayırmak için Canny operatörü kullanılmıştır. Bu çalışmada sınırlı ultrason over görüntüsünü sınıflandıran CNN mimarisi geliştirilmiş ve mimarinin optimum folikül tespit yöntemindeki başarısı sunulmuştur. Wiener Filtresi kullanılarak uyarlanabilir eşikleme ile %97.63' lük en yüksek folikül tespit doğruluğu elde edilmiştir. Ayrıca CNN mimarisi kullanılarak yumurtalıkların ultrason görüntüleri "normal" veya "polikistik over sendromu" olarak segmente edilmemiş over görüntüleri için %65,81 ve segmente edilmiş görüntüler için %77.81 sınıflandırma doğruluğu sınıflandırılmıştır. Önerilen yöntemin yanı sıra, sınırlı veri kümesinde oldukça başarılı olan SqueezeNet tabanlı transfer öğrenme kullanılarak sınıflandırma yapıldı ve segmente edilmemiş görüntüler için %74,18, segmente edilmiş görüntüler için %75.54 sınıflama doğrulupu elde edildi. Sonuçlar, Wiener filtresinin uyarlamalı eşikleme ile kombinasyonunun folikül tespitinde oldukça başarılı olduğunu ve CNN'nin önceden işlenmiş ultrason görüntülerini kullanarak yumurtalıkları daha iyi sınıflandırabildiğini göstermektedir.

The aim of this study was to determine the best method for follicle detection using ovarian ultrasound images and to classify the ultrasound images as pcos or normal ovaries using the proposed CNN architecture. Two different methods for follicle detection have been proposed to evaluate pcos. For this purpose, the Median, the Mean, the Wiener, and the Gaussian filters were tested using standard and adaptive thresholds. Second, Gaussian filtering, Discrete Wavelet Transform, and k-means clustering algorithms were tested. The Canny operator separates follicles from the background in the segmentation phase. In this study, a CNN architecture that classifies limited ultrasound ovary images was developed, and its success in the best follicle detection method was presented. The highest follicle detection accuracy of 97.63% was achieved with adaptive thresholding using a Wiener filter. Besides, the ultrasound images of the ovaries were classified as "normal" or "polycystic ovary syndrome" using CNN architecture with classification accuracy of 65.81% for unsegmented ovarian images and 77.81% for segmented images. In addition to the proposed method, classification was performed using SqueezeNet-based transfer learning, which was successful in limited datasets, and 74.18% classification accuracy was achieved for the unsegmented images and 75.54 % for segmented images . The results show that the combination of the Wiener filter with adaptive thresholding was quite successful in follicle detection and that the CNN can better classify ovaries using preprocessed ultrasound images.

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