Politeknik Dergisi 2147-9429 Gazi Üniversitesi 10.2339/politeknik.1788796 Fiber Technology Lif Teknolojisi Faktöriyel Tasarım ile Çözücü Sisteminin Elektroeğrilmiş Polikaprolakton Lif Çapına Etkisi Factorial Design Analysis of Solvent System Influence on Electrospun Polycaprolactone Fiber Diameter https://orcid.org/0000-0002-8635-666X Başkan Bayrak Havva Sabanci University 03 29 2026 29 3 1 9 09 22 2025 12 08 2025 Copyright © 1998, Politeknik Dergisi 1998 Politeknik Dergisi

Solvent seçimi, elektroeğirme yöntemindeki en kritik parametrelerden biri olup, elde edilen nanoliflerin çapını önemli ölçüde etkilemektedir. Bu çalışmada, çözelti konsantrasyonu, çözücü karışım oranı (Tetrahidrofuran (THF)–N, N Dimetilformamid (DMF)), uygulanan voltaj, iğne-toplayıcı mesafesi ve besleme hızı gibi parametrelerin sistematik olarak değiştirilmesiyle polikaprolakton (PCL) nanolifleri elektroeğirme yöntemiyle üretilmiştir. Çözelti karışımının düşük dielektrik sabitini dengelemek amacıyla, çözücü sistemi olarak THF-DMF kullanılmıştır. Elektroeğirme parametrelerinin, özellikle THF/DMF oranının lif çapı üzerindeki etkisi, 2⁴ tam faktöriyel deney tasarımıyla incelenmiştir. Lif morfolojisi Taramalı Elektron Mikroskobu (SEM) ile karakterize edilmiş, istatistiksel anlamlılık ise varyans analizi (ANOVA) ile değerlendirilmiştir. SEM ve ANOVA sonuçları, lif çapı üzerinde en büyük etkinin çözelti konsantrasyonundan kaynaklandığını, ancak THF/DMF oranının da nanolif çapının küçültülmesinde önemli bir rol oynadığını göstermiştir. Bulgular, yüksek çözelti konsantrasyonlarında daha yüksek THF/DMF oranının işlem kararlılığını artırarak daha ince PCL nanoliflerin elde edilmesini sağladığını, buna karşılık düşük konsantrasyonlarda daha düşük oranların daha uygun olduğunu ortaya koymuştur.

Solvent selection is one of the essential parameters in electrospinning, significantly influencing the diameter of the resulting nanofibers. In the present study, polycaprolactone (PCL) nanofibers were electrospun by systematically varying electrospinning parameters, including solution concentration, solvent blend ratio (Tetrahydrofuran (THF)–N, N Dimethylformamide (DMF)), applied voltage, needle tip-to-collector distance, and feed rate. Herein, THF-DMF was utilized as a solvent system to address the low dielectric constant of the solution. The effect of electrospinning parameters, particularly the THF/DMF solvent ratio, on the fiber diameter was examined using a 2⁴ full factorial experimental design. Fiber morphology was characterized by Scanning Electron Microscopy (SEM), and statistical significance was assessed by analysis of variance (ANOVA). Both SEM and ANOVA results demonstrated that while solution concentration had the greatest influence on fiber diameter, the THF/DMF ratio also played a significant role in reducing nanofiber diameter. The findings indicated that a higher THF/DMF ratio improved process stability and produced finer PCL nanofibers at high solution concentrations, whereas a lower ratio was more favorable at dilute concentrations

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