sdü tıp fak derg

Medical Journal of Süleyman Demirel University

2602-2109

Süleyman Demirel Üniversitesi

10.17343/sdutfd.1252498

Clinical Sciences

Klinik Tıp Bilimleri

SAĞLIKLI ÇOCUKLARDA KARACİĞER ELASTİKİYETİNİN pSWE VE 2D-SWE TEKNİKLERİ İLE DEĞERLENDİRİLMESİ

EVALUATION OF LIVER ELASTICITY USING pSWE AND 2D-SWE TECHNIQUES IN HEALTHY CHILDREN

https://orcid.org/0000-0003-4704-4759

Aydın

Hüseyin

Süleyman Demirel Üniversitesi Tıp Fakültesi Radyoloji Anabilim Dalı

https://orcid.org/0000-0002-3182-1990

İssi

Fatma

SÜLEYMAN DEMİREL ÜNİVERSİTESİ, TIP FAKÜLTESİ

03 14 2023

30 1 69 77 02 17 2023 02 27 2023

1994

Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi

AmaçShare wave elastografi (SWE), karaciğer sertliğininon-invaziv olarak değerlendirebilen yeni bir ultrasonografitekniğidir. Yetişkinlerde SWE'nin etkinliği çoksayıda çalışmayla gösterilmiştir, ancak pediatrik gruplardaçok az SWE çalışması vardır. Karaciğer sertliğideğerleri (KSD), cihaza ve kullanılan SWE yönteminegöre değişiklik gösterdiğinden, standart referans değerlerihenüz oluşturulmamıştır. Bu çalışmanın amacı,iki farklı SWE yöntemine göre, sağlıklı çocuklardanormal karaciğerin referans sertlik değerlerini belirlemekti.Gereç ve YöntemKaraciğer sertliği değerleri, 8-18 yaş arası 107 sağlıklıçocukta, iki farklı SWE yöntemi olan point SWE(pSWE) ve 2-dimentional SWE (2D-SWE) ile ölçüldü.pSWE (EPQ) ve 2D-SWE (EQI) ölçümleri aynı cihaz(Philips Epiq Elite) ile, tek seansta ve en az 4 saataç kaldıktan sonra alındı. Cinsiyet, yaş, vücut kitle indeksi(VKİ), bazı biyokimyasal belirteçler ((açlık kanşekeri, aspartat aminotransferaz (AST), alanin aminotransferaz(ALT), albümin, trombosit, INR gibi)) vekaraciğer boyutunun, KSD’ye etkisi araştırıldı.BulgularOrtalama KSD, pSWE ile 4,04±0,84kPa ((%95 güvenaralığı (CI):3,67-4,42)) ve 2D-SWE ile 4,41±0,71kPa(%95 CI:4,09-4,72) bulundu. Üst sınır KSD'ler sırasıyla4,42kPa ve 4,72kPa idi. 2D-SWE'de ölçülenKSD'ler, pSWE'den daha yüksekti ((sırasıyla medyan;min-maks, 4,34kPa; 2,82-6kPa ve 3,86kPa; 2,55–5,78, (r=0,59, p

ObjectiveShear wave elastography (SWE) is a newultrasonography technique that can non-invasivelyevaluate liver stiffness. The efficacy of SWE in adultshas been demonstrated by numerous studies, butthere are few SWE studies of pediatric groups. Sincethe liver stiffness values (LSV) vary according to thedevice and the SWE method used, standard referencevalues have not been established as yet. The aim ofthis study was to establish the reference values ofnormal liver stiffness in healthy children according tothe two SWE methods.Materials and MethodLiver stiffness values were measured using the twodifferent SWE methods of point SWE (pSWE) and2-dimensional SWE (2D-SWE) in 107 healthy childrenaged 8-18 years with no liver disease. The pSWE(EPQ) and 2D-SWE (EQI) measurements were takenin one session on the same device (Philips Epiq Elite)and after at least 4 hours of fasting. The effects onliver elasticity values were investigated of gender,age, body mass index (BMI), some biochemicalmarkers (such as fasting blood glucose, aspartateaminotransferase (AST), alanine aminotransferase(ALT), albumin, platelet, INR) and liver size.ResultsThe mean LSV was 4.04±0.84kPa ((95% confidenceinterval (CI):3.67-4.42)) on pSWE and 4.41±0.71kPa(95% CI:4.09-4.72) on 2D-SWE. The upper limit LSVswere found to be 4.42kPa and 4.72kPa, respectively.The LSVs measured on 2D-SWE were found to behigher than on pSWE ((median; min-max, 4.34kPa;2.82-6kPa and 3.86kPa; 2.55–5.78, respectively,(r=0.59, p

Children liver stiffness ultrasound shear wave elastography two-dimensional shear wave imaging

Çocuk karaciğer sertliği ultrason shear wave elastografi iki boyutlu-shear wave elastografi.

None

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