sdü tıp fak derg Medical Journal of Süleyman Demirel University 2602-2109 Süleyman Demirel Üniversitesi Dentistry Diş Hekimliği ASTIMDA ANALJEZİK (NSAİİ) KULLANIMI Aşcı Halil Cankara Fatma Özer Mehmet 09 30 2012 19 3 111 119 01 19 2011 Copyright © 1994, Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi 1994 Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi

Astım; T lenfositler, eozinofiller ve mast hücreleri başta olmak üzere birçok hücre ve hücresel elementlerin rol oynadığı havayollarının kronik inflamatuvar bir hastalığıdır. Tedavisinde başlıca kortikosteroidler, beta agonistler, antikolinerjikler, kromonlar (mast hücresi stabilizatörleri), lökotrien antagonistleri ve teofilin kullanılmaktadır. Ancak bu ilaçlar başka endikasyonlar (ağrı, enfeksiyon gibi) sırasında kullanılan ilaçlarla etkileşerek astımı provake edebilir. Bu etkileşimler bazı ilaçlarda farmakokinetik düzeyde bazı ilaçlarda ise farmakodinamik düzeylerde olmaktadır. Bu derlemede nonsteroid antiinflamatuar ilaçlar ile astımlı hastalarda kullanılan ilaçlar arasındaki etkileşimden bahsedilecektir.

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