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            <front>

                <journal-meta>
                                                                <journal-id>sdü tıp fak derg</journal-id>
            <journal-title-group>
                                                                                    <journal-title>Medical Journal of Süleyman Demirel University</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">2602-2109</issn>
                                                                                            <publisher>
                    <publisher-name>Süleyman Demirel Üniversitesi</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id/>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Dentistry</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Diş Hekimliği</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <trans-title-group xml:lang="en">
                                    <trans-title>Clinical experience with retroperitoneal soft tissue sarcomas</trans-title>
                                </trans-title-group>
                                                                                                                                                                                                <article-title>Retroperitoneal yumuşak doku sarkomunda klinik deneyimlerimiz</article-title>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                <name>
                                    <surname>Özçelik</surname>
                                    <given-names>Çağlar</given-names>
                                </name>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Zihni</surname>
                                    <given-names>İsmail</given-names>
                                </name>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Karaköse</surname>
                                    <given-names>Oktay</given-names>
                                </name>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Pülat</surname>
                                    <given-names>Hüseyin</given-names>
                                </name>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Eroğlu</surname>
                                    <given-names>Hasan</given-names>
                                </name>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20141230">
                    <day>12</day>
                    <month>30</month>
                    <year>2014</year>
                </pub-date>
                                        <volume>21</volume>
                                        <issue>4</issue>
                                        <fpage>114</fpage>
                                        <lpage>117</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20140618">
                        <day>06</day>
                        <month>18</month>
                        <year>2014</year>
                    </date>
                                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 1994, Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi</copyright-statement>
                    <copyright-year>1994</copyright-year>
                    <copyright-holder>Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi</copyright-holder>
                </permissions>
            
                                                                                                <trans-abstract xml:lang="en">
                            <p>Aim/Objective: Retroperitoneal soft tissue sarcoma; epidemiological, histopathological features of cases in our clinic, treatments and their clinical courses were compared with the literature. Materials and Methods: Records of 7 patients who were operated in Surgical Oncology Clinics of Süleyman Demirel University between 2007-2013 after being detected with primary retroperitoneal- intraperitoneal masses in imagings and being reported as soft tissue tumor in histopathological examination were analyzed retrospectively. Results: The patients were 6 males and 1 female. Abdominal tomography was applied to all patients and in imagings there were both intraperitoneal and retroperitoneal masses in 4 patients (57,1%), left retroperitoneal masses in 2 patients (28,6%) and intraperitoneal mass in 1 patient (14,3%). Distant metastases weren’t detected in any of the patients at the time of diagnosis. While mass excision was done in 2 patients, enbloc organs resection (colon and kidney) was done along with excision in 3 patients, two patients were admitted as unresectable. In pathological examination, 42,9% (in 3 patient) good differential liposarcoma, 28,6% (in 2 patient) leiomyosarcoma and 14.3% (1 patient) dedifferentiated liposarcoma and rhabdomyosarcoma were detected. Recurrence developed in 2 patients who were applied mass excision in 11th month (10th month and 12th month) on the average. Lung metastases developed in one patient in the 6th month who were applied enbloc organ and mass resection. Conclusion: Retroperitoneal soft tissue sarcomas are rarely seen. However, recurrence often develops generally due to incomplete surgery. Therefore, aggressive surgery is recommended in these tumors in order to provide negative surgery border</p></trans-abstract>
                                                                                                                                    <abstract><p>Amaç: Retroperitoneal yumuşak doku sarkomlarında kliniğimizdeki vakalarınepidemiyolojik, histopatolojik özellikleri, uygulanan tedaviler ve klinik seyirleri literatür ilekarşılaştırıldı. Gereç ve Yöntem: Süleyman Demirel Üniversitesi Cerrahi Onkoloji Kliniğinde2008-2013 yılları arasında görüntülemelerde primer retroperitoneal-intraperitoneal kitlesaptanıp operasyona alınan ve histopatolojik incelemesi yumuşak doku tümörü olarakraporlanan 7 hastanın kayıtları retrospektif olarak incelendi. Bulgular: Hastaların 6’sı erkek1 kadındı. Tüm hastalara abdominal tomografi uygulandı ve görüntülemede 4 hastada(%57,1) hem intraperitoneal hem retroperitonel 2 hasta (%28,6) sol retroperitonealde ve1 hastada (%14,3) intraperitoneal kitle mevcuttu. Tanı anında hiçbir hastada uzak organmetastazı saptanmadı. Hastaların 2’sine kitle eksizyonu, 3’üne kitle ile birlikte en-blok organrezeksiyonu (kolon ve böbrek) yapılırken 2 hasta rezektable değildi. Patolojik incelemede%42,9 (3 hasta) iyi differansiye liposarkom, %28,6 (2 hasta) leiomyosarkom, %14,3 (1hasta) rabdomyosarkom ve indiferansiye liposarkom saptandı. Kitle eksizyonu uygulanan 2hastada ortalama 11.ayında (10.ay ve 12.ay) nüks gelişti. Kitle ile en blok organ rezeksiyonuyapılan bir hastada ise 6.ayında akciğer metastazı gelişti. Sonuç: Retroperitoneal yumuşakdoku sarkomları nadir izlenmektedir. Ancak genellikle yetersiz cerrahiye bağlı olarak nükssıklıkla gelişmektedir. Bundan dolayı negatif cerrahi sınır sağlamak için bu tümörlerdeagresif cerrahi önerilmektedir.</p></abstract>
                                                            
            
                                                                                        <kwd-group>
                                                    <kwd>Sarkom</kwd>
                                                    <kwd>   yumuşak doku</kwd>
                                                    <kwd>   retroperiton</kwd>
                                                    <kwd>   rezeksiyon</kwd>
                                            </kwd-group>
                            
                                                <kwd-group xml:lang="en">
                                                    <kwd>Sarcoma</kwd>
                                                    <kwd>   soft tissue</kwd>
                                                    <kwd>   retroperitoneal</kwd>
                                                    <kwd>   resection</kwd>
                                            </kwd-group>
                                                                                                                                        </article-meta>
    </front>
    <back>
                            <ref-list>
                                    <ref id="ref1">
                        <label>1</label>
                        <mixed-citation publication-type="journal">Sogaard AS, Laurberg JM, Sorensen M, Sogaard OS, Wara P, Rasmussen P, Laurberg S. Intraabdominal and retroperitoneal soft-tissue sarcomas-outcome of surgical treatment in primary and recurrent tumors. World J Surg Oncol. 2010; 12: 8-81.</mixed-citation>
                    </ref>
                                    <ref id="ref2">
                        <label>2</label>
                        <mixed-citation publication-type="journal">Lewis JJ, Brennan MF. Soft tissue sarcomas. Curr Probl Surg. 1996; 33: 817–872.</mixed-citation>
                    </ref>
                                    <ref id="ref3">
                        <label>3</label>
                        <mixed-citation publication-type="journal">Miettinen M, Sarlomo-Rikala M, Sobin LH, Lasota J. Gastrointestinal stromal tumors and leiomyosarcomas in the colon: a clinicopathologic, immunohistochemical, and molecular genetic study of 44 cases. Am J Surg Pathol. 2000; 24: 1339–1352.</mixed-citation>
                    </ref>
                                    <ref id="ref4">
                        <label>4</label>
                        <mixed-citation publication-type="journal">Liles JS, Tzeng CW, Short JJ, Kulesza P, Heslin MJ. Retroperitoneal and intra-abdominal sarcoma. Curr Probl Surg. 2009; 46: 445-503.</mixed-citation>
                    </ref>
                                    <ref id="ref5">
                        <label>5</label>
                        <mixed-citation publication-type="journal">Lewis JJ, Leung D, Woodruff JM, Brennan MF. Retroperitoneal soft-tissue sarcoma: analysis of 500 patients treated and followed at a single institution. Ann Surg. 1998; 228: 355– 365.</mixed-citation>
                    </ref>
                                    <ref id="ref6">
                        <label>6</label>
                        <mixed-citation publication-type="journal">Miettinen M, Sarlomo-Rikala M, Lasota J. Gastrointestinal stromal tumors: recent advances in understanding of their biology. Hum Pathol. 1999; 30: 1213–1220.</mixed-citation>
                    </ref>
                                    <ref id="ref7">
                        <label>7</label>
                        <mixed-citation publication-type="journal">Grimer R, Judson I, Peake D, Seddon B. Guidelines for the management of soft tissue sarcomas. Sarcoma. 2010; 2010: 506182.</mixed-citation>
                    </ref>
                                    <ref id="ref8">
                        <label>8</label>
                        <mixed-citation publication-type="journal">Zahm SH, Fraumeni JF Jr. The epidemiology of soft tissue sarcoma. Semin Oncol 1997; 24: 504-514.</mixed-citation>
                    </ref>
                                    <ref id="ref9">
                        <label>9</label>
                        <mixed-citation publication-type="journal">John E. Mullinax, MD, Jonathan S. Zager, MD, and Ricardo J. Gonzalez, MD. Current Diagnosis and Management of Retroperitoneal Sarcoma. Cancer Control. 2011; 18: 177- 187.</mixed-citation>
                    </ref>
                                    <ref id="ref10">
                        <label>10</label>
                        <mixed-citation publication-type="journal">Lahat G, Dhuka AR, Lahat S, Smith KD, Pollock RE, Hunt KK, Ravi V, Lazar AJ, Lev D. Outcome of locally recurrent and metastatic angiosarcoma. Ann Surg Oncol. 2009; 16: 2502-2509.</mixed-citation>
                    </ref>
                                    <ref id="ref11">
                        <label>11</label>
                        <mixed-citation publication-type="journal">Bonvalot S, Rivoire M, Castaing M, Stoeckle E, Le Cesne A, Blay JY, Laplanche A. Primary retroperitoneal sarcomas: a multivariate analysis of surgical factors associated with local control. J Clin Oncol. 2009; 27: 31-37.</mixed-citation>
                    </ref>
                                    <ref id="ref12">
                        <label>12</label>
                        <mixed-citation publication-type="journal">Russo P, Kim Y, Ravindran S, Huang W, Brennan MF. Nephrectomy during operative management of retroperitoneal sarcoma. Ann Surg Oncol. 1997; 4: 421- 424.</mixed-citation>
                    </ref>
                                    <ref id="ref13">
                        <label>13</label>
                        <mixed-citation publication-type="journal">Gronchi A, Lo Vullo S, Fiore M, Mussi C, Stacchiotti S, Collini P, Lozza L, Pennacchioli E, Mariani L, Casali PG. Aggressive surgical policies in a retrospectively reviewed single-institution case series of retroperitoneal soft tissue sarcoma patients. J Clin Oncol. 2009; 27: 24-30.</mixed-citation>
                    </ref>
                                    <ref id="ref14">
                        <label>14</label>
                        <mixed-citation publication-type="journal">Van Dalen T, Hennipman A, Van Coevorden F, Hoekstra HJ, van Geel BN, Slootweg P, Lutter CF, Brennan MF, Singer S. Evaluation of a clinically applicable post-surgical classification system for primary retroperitoneal soft-tissue sarcoma. Ann Surg Oncol. 2004; 11: 483-90.</mixed-citation>
                    </ref>
                            </ref-list>
                    </back>
    </article>
